Pt/TiO2 Catalyzed Hydrogenation of Benzoic Acid with Unprecedented High Activity

Pt/TiO2 Catalyzed Hydrogenation of Benzoic Acid with Unprecedented High Activity | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Pt/TiO2 Catalyzed Hydrogenation of Benzoic Acid with Unprecedented High Activity Miao Guo, Xiangtao Kong, Chunzhi Li, Qihua Yang This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-108586/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 16 Apr, 2021 Read the published version in Communications Chemistry → Version 1 posted You are reading this latest preprint version Abstract The hydrogenation of benzoic acid (BA) to corresponding cyclohexanecarboxylic acid has important industry and academia significance, however, the electron deficient aromatic ring and the catalyst “poison” by carboxyl group make BA hydrogenation as one of the most challenging transformations. Herein, we found that Pt NPs deposited on TiO 2 were very effective for BA hydrogenation with a record TOF of 4490 h − 1 under 80 o C and 50 bar H 2 in hexane, one order higher than the reported results. DFT calculation showed that Pt NPs had a weaker interaction with BA than Ru and Pd NPs commonly used for BA hydrogenation, which improved the toxicity resistance of catalyst to BA. Pt/TiO 2 catalysts with electron deficient and electron enriched Pt sites were successfully synthesized by modifying the electron transfer direction between Pt and TiO 2 . Isotopic experiments suggested the participation of dissociated H from carboxyl group in BA hydrogenation. Consequently, the electron deficient Pt sites with stronger adsorption of BA were more active than electron rich Pt sites in BA hydrogenation. In addition to BA, terephthalic acid, iso-phthalic acid, trimesic acid and other BA derivatives could also be efficiently converted to corresponding aromatic saturated products, demonstrating the wide substrate scope of Pt/TiO 2 . Catalysis Pt/TiO2 Hydrogenation Anti-Poison Benzoic Acid Terephthalic Acid Trimesic Acid Figures Figure 1 Figure 2 Figure 3 Figure 4 Introduction The selective hydrogenation of benzoic acid (BA) or its derivatives has been widely used for the production of fine chemicals, intermediates and industrial raw materials [1-3]. For example, BA hydrogenation to cyclohexanecarboxylic acid (CCA) is an important step in the production of nylon-6 in industry [4-5]. However, the need to overcome the high resonance energy of the electron deficient aromatic ring [6] and the catalyst “poison” by carboxyl group [7,8] make BA hydrogenation as one of the most challenging transformations. Harsh conditions (100~250 o C, 50~150 bar H 2 ) are typically required in order to obtain high BA conversion, which inevitably causes the decrease in selectivity due to the side reactions of decarboxylation and over hydrogenation [9,10]. Up to now, various supported metal catalysts (e.g. Pd, Ru, Rh, and Ni) have been used for BA hydrogenation under relatively mild conditions, but the activity is still relatively low [11,12]. Previous results demonstrated that most of the supported metal catalysts were active only with water as solvent under mild condition and showed low or no activity in organic solvents for BA hydrogenation [13]. The typical solvation effect is possibly related with the preferential adsorption of aromatic ring on metal surface induced by the interaction of carboxyl group with H 2 O molecules [13,14] and the participation of H* from the dissociated H 2 O molecules in the reaction [2,15]. Though water could modify the adsorption mode of substrates, it may also block the surface active sites [16,17]. Taken together the low H 2 solubility in water (e.g. 0.792 mmol L -1 , 298.15 K, 1 atm H 2 ) [18], water is not a good choice for efficient BA hydrogenation under mild conditions. Carboxylates tend to strongly adsorb on metal surface, which significantly deteriorates the catalytic activity through so-called “poison effects” [19]. In contrast, the adsorption of aromatic ring of BA on metal surface is weak considering that the electron deficient phenyl ring does not easily bind to the surface unoccupied d -metal orbitals via π-bonds [20,21]. This may be the reason that most metal NPs showed relatively low activity in BA hydrogenation. Recently, our group reported that the activity of Ru NPs was greatly enhanced in BA hydrogenation by tuning the adsorption mode of BA on metal surface with phosphine ligands [2]. Therefore, to realize the efficient BA hydrogenation, the supported metal NPs with appropriate adsorption strength towards carboxyl group and aromatic ring may be the good choice. Herein, we reported that Pt/TiO 2 is a highly active and selective catalyst for BA hydrogenation under mild conditions in either organic solvents or water by screening a series of supported metal NPs. Pt/TiO 2 gives a record activity with apparent TOF up to 4490 h -1 under 80 o C and 50 bar H 2 in hexane. The studies indicated that electron deficient Pt sites were more active than electron rich Pt sites, possibly due to the facilitated participation of H from carboxyl group in BA hydrogenation on electron deficient Pt sites. Results And Discussion Screening the Supported Metal NPs for BA Hydrogenation Firstly, commercially available carbon supported metal NPs were tested in BA hydrogenation ( Figure 1a ). Pd/C (5 wt%) and Ru/C (5 wt%) were almost inactive in hexane at 40 °C and 10 bar H 2 , similar to previous report [13, 22]. To our delight, Pt/C (5 wt%) afforded 51% conversion with > 99% selectivity to CCA under identical conditions. Inspired by this result, different types of supported Pt catalysts with Pt loading of 2 wt% were screened in BA hydrogenation ( Figure 1a ) considering that the support with different acid/base or redox properties may influence the catalytic performance of supported metal NPs [23,24]. Pt/MgO, Pt/CeO 2 , Pt/CN and Pt/γ-Al 2 O 3 afforded less than 20% BA conversion. Pt/SiO 2 and Pt/ZrO 2 gave moderate BA conversion respectively of 65% and 35%. Pt/TiO 2 afforded high BA conversion of 96% with > 99% selectivity to CCA. The catalyst screen results suggest that the base and acid support respectively deteriorate [25] and promote [26] the aromatic hydrogenation activity of Pt in BA hydrogenation. Even at 25 o C and 1 bar H 2 , Pt/TiO 2 could still afforded > 99% BA conversion and CCA selectivity ( Table 1 ). The apparent TOF of Pt/TiO 2 was calculated to be 115 h -1 at 25 o C, 1 bar H 2 and 638 h -1 at 40 o C, 10 bar H 2 . To increase S/C ratio is very important for practical applications. Thus, the BA hydrogenation was performed at S/C as high as 1200 over Pt/TiO 2 in the presence of acetic acid to facilitate the dissolution of BA in hexane. Under such harsh conditions, Pt/TiO 2 could still afford 90% conversion with the apparent TOF of 4490 h -1 at 80 °C and 50 bar H 2 , an order of magnitude higher than the supported metal NPs ever reported ( Table S1 ). Table 1 . The catalytic performance of Pt/TiO 2 catalysts in the hydrogenation of BA. a a Reaction conditions: 40 o C, 10 bar H 2 , 1 h. b Selectivity to CCA. Only less than 5% cyclohexenecarboxylic acid (CEA) was detected as the intermediate during the reaction process. c Apparent TOF is calculated as moles of converted BA per mole of Pt per hour with the conversion less than 30%. The values in parentheses were the TOF calculated based on Pt dispersion. d 25 o C, 1 bar H 2 , 3 h. e 80 o C, 50 bar H 2 , 1.5 h. The catalyst screen results suggest that Pt NPs are active for BA hydrogenation in hexane irrespective of the supports, different from Pd and Ru NPs. Density functional theory (DFT) calculation showed that the adsorption energies of BA on Pt (111), Pd (111) and Ru (1000) is respectively of -1.53 eV, -2.87 eV and -2.95 eV, showing the stronger adsorption of BA on Ru and Pd than on Pt and the adsorption energies of acetic acid on Pt (111), Pd (111) and Ru (1000) gave similar tendency ( Figure 1b ). This suggests that the relative weak adsorption strength of BA on Pt may contribute to the high activity of Pt NPs in BA hydrogenation. Pt/TiO 2 was active in hexane, H 2 O, cyclohexane, isopropyl alcohol and EtOH ( Tables 1 and S2 ), showing the wide solvent tolerance. Even using acetic acid as the solvent, 68% conversion could still be obtained, showing the high anti-carboxyl poisoning ability of Pt NPs. The product selectivity to CCA is > 93% for all the solvents investigated with cyclohexenecarboxylic acid as the side product. BA conversion in aprotic and oxygenate free solvents (e.g. n-hexane) is much higher than that in protic and oxygenate solvents. The decreased hydrogenation rate may be related to the hydrogen bonding of protic solvent and BA, which may hinder the BA adsorption on Pt surface [27]. It is noteworthy to mention that the activity of Pt/TiO 2 was much lower in water than in hexane, which is possibly related with the active sites blocking and low solubility of H 2 in water [16, 18, 28]. The Influence of Electronic and Geometric Structures of Pt on BA Hydrogenation Pt/TiO 2 -200 and Pt/TiO 2 -450 were prepared by treatment of Pt/TiO 2 under H 2 atmosphere at 200 and 450 o C, respectively. The TEM, HRSEM and HAADF-STEM images of Pt/TiO 2 , Pt/TiO 2 -200 and Pt/TiO 2 -450 showed the uniform distribution of Pt with particle size of 2.9 nm, showing that no aggregation of Pt NPs occurred during the H 2 treatment process ( Figures 2, S1-S3 ). The CO chemisorption results showed that Pt dispersion for Pt/TiO 2 , Pt/TiO 2 -200 and Pt/TiO 2 -450 was respectively of 29.0, 22.6 and 24.2 ( Table 2 ). The Pt dispersion of Pt/TiO 2 -200 and Pt/TiO 2 -450 slightly decreased, which may be caused by the weak adsorption ability of CO at the interface of Pt and TiO 2 after H 2 treatment [29]. The Pt dispersion obtained by H 2 molecules was almost the same for Pt/TiO 2 , Pt/TiO 2 -200 and Pt/TiO 2 -450 ( Table 2 ). It should be noted that the Pt dispersion of Pt/TiO 2 before and after H 2 treatment was comparable, showing that the H 2 treatment of Pt/TiO 2 did not induce the severe coverage of Pt surface by TiO x , which may be due to pre-nucleation reduction method for the synthesis of the parent Pt/TiO 2 [30,31]. The reaction profiles for BA hydrogenation displayed that more BA was converted to CCA with Pt/TiO 2 than with Pt/TiO 2 -450 within the same reaction time ( Figure S4 ). Under similar conditions, Pt/TiO 2 with > 99% conversion was more active than Pt/TiO 2 -200 and Pt/TiO 2 -450 with conversion respectively of 59% and 10% ( Table 1 ). To make reasonable comparisons, the TOF of Pt/TiO 2 catalysts was normalized to Pt dispersion obtained with CO chemisorption. Pt/TiO 2 , Pt/TiO 2 -200 and Pt/TiO 2 -450 respectively afforded TOF of 2200 h -1 , 757 h -1 and 103 h -1 , further confirming that Pt/TiO 2 is more active than Pt/TiO 2 -200 and Pt/TiO 2 -450. Generally, the H 2 treatment of Pt/TiO 2 at high temperature would induce the change in electronic and geometric structure of Pt due to the strong metal-support interaction (SMSI) [32]. In order to understand the different catalytic properties of Pt/TiO 2 catalysts, the electronic structure of Pt was firstly characterized by X-ray photoelectron spectroscopy (XPS) ( Figure 2c, Table 2) . Compared with Pt/TiO 2 , Pt 4f binding energies (BEs) of Pt/TiO 2 -200 and Pt/TiO 2 -450 showed an obvious downward shift respectively by 0.3 eV and 0.4 eV, suggesting that Pt/TiO 2 had more electron deficient Pt sites than Pt/TiO 2 -200 and Pt/TiO 2 -450. The decrease in Pt 4f BEs indicates the charge transfer from Ti cations to Pt NPs induced by SMSI [33], which was further confirmed by the higher Ti 2p 3/2 BEs of Pt/TiO 2 than those of Pt/TiO 2 -200 and Pt/TiO 2 -450 ( Figure S5 ). It should be noted that Ti 2p 3/2 BEs of Pt/TiO 2 were lower than those of TiO 2 , implying the electron transfer from Pt to Ti cations. The Pt 0 /Pt δ+ ratio of Pt/TiO 2 increased from 68/32 to 74/26 after heat treatment in H 2 , showing that the reduction degree of Pt increased at high temperature ( Table 2 ). The electronic structure of Pt/TiO 2 catalysts could be facilely modified due to the electron-withdrawing ability of acidic TiO 2 support [34] and the SMSI effect of Pt-TiO 2 system [35]. The electronic and geometric structures of Pt NPs were further characterized with in situ diffuse reflectance infrared Fourier transform spectra (DRIFTS) of CO chemisorption ( Figure 2d ). DRIFTS of adsorbed CO for Pt/TiO 2 showed four distinct υ CO bands in the linear carbonyl region located at approximately 2115, 2096, 2079 and 2062 cm -1 . The band at 2115 cm -1 can be assigned to Pt δ+ [36]. The lower frequency vibrational stretch at 2062 cm -1 was assigned to CO molecules adsorbed on low-coordination Pt-edge and -corner sites. The higher frequency vibrational stretch at 2096 and 2079 cm −1 can be assigned to CO molecules that are adsorbed on the Pt (111) terrace sites (the coordination number of 9) and Pt (110) (the coordination number of 8), respectively [37-42]. The DRIFTS of adsorbed CO for Pt/TiO 2 -200 was similar to that of Pt/TiO 2 with the exception that the red shift of the vibration peaks was observed, showing the electron donation from Ti cations to Pt due to SMSI effect. The lower activity of Pt/TiO 2 -200 than Pt/TiO 2 suggested that Pt with electron deficient surface was favorable for the BA hydrogenation considering that the two catalysts had similar geometric surface structure of Pt. Table 2 . Pt dispersion measured with H 2 /CO chemisorption, Pt 4f and Ti 2p binding energies by XPS of Pt catalysts. Cat. Pt dispersion (%) a Pt dispersion (%) b Ti 2p 3/2 (eV) c Pt 4f 7/2 (eV) c Pt 0 /Pt + (%) c Pt/TiO 2 29.0 48.4 458.4 71.1 68/32 Pt/TiO 2 -200 22.6 49.6 458.6 70.8 70/30 Pt/TiO 2 -450 24.2 44.6 458.6 70.7 74/26 TiO 2 -- -- 458.5 -- -- a Data calculated from CO chemisorption results. b Data calculated from H 2 chemisorption results. c Data obtained from XPS results. The DRIFTS of adsorbed CO for Pt/TiO 2 -450 is quite different from those of Pt/TiO 2 and Pt/TiO 2 -200. The obvious change in peak intensities of Pt/TiO 2 -450 suggested the reconstruction of surface Pt atoms under high temperature H 2 treatment [39]. The relatively high peak intensity at 2083 cm -1 indicated that Pt surface had more well-ordered Pt surface (111). The peak assigned to Pt (111) gradually red shifted with H 2 treatment temperature increasing, implying the TiO 2 donates more electrons to Pt at higher temperature [43]. In comparison with Pt/TiO 2 and Pt/TiO 2 -200, the much lower activity of Pt/TiO 2 -450 indicated that the electron deficient and low coordination Pt sites may be active for BA hydrogenation. The reaction order of BA and H 2 was investigated with Pt/TiO 2 and Pt/TiO 2 -450 as representative catalysts considering that the reaction kinetics are particularly sensitive to the active Pt structure ( Figures 3a, 3b) [44,45]. The order of BA hydrogenation with respect to BA is respectively of -0.29, and 0.45 for Pt/TiO 2 , and Pt/TiO 2 -450, implying the stronger adsorption of BA on Pt/TiO 2 than on Pt/TiO 2 -450. The reaction rate of Pt/TiO 2 increased along with the H 2 pressure and no plateau was observed with H 2 pressure range of 6 to 40 bar, which was possibly related with the strong adsorption of BA. The reaction order with respective to H 2 for Pt/TiO 2 and Pt/TiO 2 -450 is +0.50 and ~0, respectively. The positive order in hydrogen for the BA hydrogenation is a logical consequence of hydrogenation being involved in rate-determining step. The kinetic results showed that the overall reaction order of BA hydrogenation on Pt/TiO 2 -450 is much larger than that on Pt/TiO 2 (+0.46 vs. +0.25, Table S3 ), indicating different reaction mechanism for the two catalysts. Temperature dependent reactivity measurements were taken to obtain apparent activation barriers with Pt/TiO 2 and Pt/TiO 2 -450 as representative ( Figure 3c ). The activation energies for Pt/TiO 2 and Pt/TiO 2 -450 were respectively of ~38 kJ mol -1 and ~56 kJ mol -1 , showing the two catalysts have different catalytic sites for BA hydrogenation [46-48]. The higher energy barriers of Pt/TiO 2 -450 explains its low activity in BA hydrogenation. The characterization data showed that the electron density of Pt NPs followed the order of Pt/TiO 2 < Pt/TiO 2 -200 < Pt/TiO 2 -450. In combination with the catalytic activity, we can infer that the electronic deficient Pt may favor the high BA hydrogenation. From kinetic data, Pt/TiO 2 and Pt/TiO 2 -450 had strong and weak adsorption towards BA, implying that electron rich Pt had weaker adsorption for BA. According to the Sabatier rule, too strong or too weak adsorption of reactants on catalysts does not favor high activity. The minus reaction order of BA over Pt/TiO 2 means that BA (or CCA) in fact is “a poison” for the catalyst, which blocked the active sites. 49 The higher reaction order of H 2 over Pt/TiO 2 than over Pt/TiO 2 -450 indicated that H 2 adsorption is relative more difficult for the former sample due to the strong BA adsorption. But Pt/TiO 2 still showed much higher activity than Pt/TiO 2 -450, suggesting that the H 2 activation played an important role in BA hydrogenation. The H 2 activation ability of the catalysts was measured using H 2 -D 2 exchange experiments ( Figure 3d, Table S4 ). The normalized HD formation rate of Pt/TiO 2 is more than 10 fold that of Pt/TiO 2 -450, showing that Pt/TiO 2 with electronic deficient Pt surface is more active for H 2 activation than Pt/TiO 2 -450 with electronic rich Pt surface. This result suggests that the high activity of Pt/TiO 2 is partly attributed to the high H 2 activation ability. The Role of the Carboxyl Group Generally, the deficient phenyl ring does not easily bond on metal surface [20], which always results in low catalytic activity [50]. However, the high activity of Pt/TiO 2 in BA hydrogenation suggests that carboxyl group may affect the hydrogenation activity. To identify the role of carboxyl group in BA hydrogenation, hydrogenation of benzotrifluoride and toluene were conducted ( Figure 4a ). Pt/TiO 2 could efficiently catalyze the hydrogenation of the above substrates to the corresponding aromatic ring hydrogenated products. The activity followed the order of BA > toluene > benzotrifluoride under similar reaction conditions. The unusual high activity of BA hydrogenation was in contrast to the previous findings that the deficient phenyl ring was difficult to be hydrogenated. This suggests that the carboxyl group may be involved in the whole reaction process although it cannot easily be hydrogenated at mild reaction conditions [10]. DFT calculation results showed that the most favorable adsorption configuration of toluene on Pt(111) was the benzene ring adsorption parallel to the metal plane, and the methyl group was far away from the Pt surface. This mainly due to better superposition of its π-orbitals with the Pt conduction band ( Figure 4b ) [51,52]. Different from toluene, BA molecule adopted a configuration that an O atom of the carboxyl group was co-adsorbed on the Pt surface. The strong adsorption of BA on Pt/TiO 2 as discussed above may be derived from the co-adsorption of carboxyl group on Pt surface [53]. The dissociated hydrogen stems from the carboxyl group may act as one of the H sources. To confirm this, a control experiment was conducted by using benzoic acid-d 5 and D 2 as reactants. The MS analysis of the product showed the appearance of molecular ion peaks at m/z of 139.2 and 138.2 with the intensity ratio of 1.9, denoting the presence of 6 deuterated and 5 deuterated CCA in the product ( Figure 4c ). An obvious sharp peak at 1.255 was observed in the 1 H-NMR spectrum of the product assigned to the H on the m- or p-position of cyclohexane ring ( Figure 4c ), further confirming the results of MS analysis. The above results show that the dissociated H from carboxyl group is involved in the hydrogenation process. To this end, the active Pt–H species from homolytic dissociation of hydrogen and dissociated H from carboxyl group attack the activated BA molecule to produce CCA. Besides, the adsorption of carboxyl group on Pt/TiO 2 favored the orientation of the aromatic ring on the Pt surface, which may facilitate the hydrogen transfer from Pt surface to BA molecules [54]. On the basis of this mechanism, the Pt with electron deficient surface favored the adsorption and dissociation of carboxyl group, which could enhance the BA hydrogenation activity. Substrate scopes of Pt/TiO 2 Pt/TiO 2 was also used for the hydrogenation of BA derivatives at mild conditions ( Table 3 ). Firstly, the hydrogenations of methyl-substituted BA (o-, m-, and p-), p-ethyl benzoic acid and p-pentyl benzoic acid were investigated and the full conversion was obtained in 6 h with the kinetically favored cis isomer [55]. The cis/trans ratio varied in the range of 20/30 to 86/14 ( Table 3, entry 1-5 ). For p-isopropyl benzoic acid, it needed 10 h to reach full conversion with the cis/trans ratio of 68/32 ( Table 3, entry 6 ). Even for p-trifluoromethylbenzoic acid with more electron deficient aromatic ring, full conversion was achieved in 10 h though S/C ratio was decreased to 50/1 ( Table 3, entry 7 ), demonstrating the high activity of Pt/TiO 2 . p-Hydroxylbenzoic acid, phenyl propionic acid and phenyl pentanoic acid could be efficiently transferred to corresponding products over Pt/TiO 2 ( Table 3, entry 8-10 ). The hydrogenation of methyl benzoate, mono-methyl terephthalate and dioctyl phthalate resulted in the formation of the aromatic hydrogenated products using Pt/TiO 2 as catalyst ( Table 3, entry 11-13 ). It should be mentioned that Pt/TiO 2 could also catalyze the hydrogenation of terephthalic acid, phthalic acid, iso-phthalic acid and even the challenging trimesic acid and trimethyl trimesate to corresponding aromatic ring saturated product under mild conditions, further demonstrating the high efficiency of Pt/TiO 2 for the hydrogenation of aromatic acids ( Table 3, entry 14-18 ). The hydrogenation of dioctyl phthalate/phthalate acid and trimesic acid/trimethyl trimesate respectively produced the trans and cis isomers, and the hydrogenation of the other substrates investigated in this paper resulted in the formation of cis isomer as the main product on the basis of NMR analysis (see SI ), which may be caused by the steric hindrance effect [56]. Table 3 . Hydrogenation of BA derivatives using Pt/TiO 2 as catalyst. a a Reaction conditions: 40 o C, 10 bar H 2 , S/C = 250, 3 mL hexane, b Selectivity to ring hydrogenation product; the cis:trans ratio was determined by 1 H-NMR results (See SI ) [57]; c Chair conformation. d S/C= 50; e 3mL H 2 O; f 1.5 mL hexane and 1.5 mL acetic acid; g 60 o C; h 60 o C, 1.5 mL H 2 O and 1.5 mL acetic acid; i 60 o C, 20 bar H 2 , 3 mL solvent (10 v/v % H 2 O in n-hexane); j 80 o C, 20 bar H 2 , 3 mL hexane (10 v/v % H 2 O in n-hexane). The recycle stability of Pt/TiO 2 was investigated using BA hydrogenation as a model reaction ( Figure 4d ). The recovered Pt/TiO 2 can be repeatedly used in the hydrogenation reactions, for example in 5 runs of our demonstration, without showing discernible decrease in the conversion of BA or the reaction selectivity. The Pt/TiO 2 after five cycles had similar particle size as the fresh one on the basis of TEM characterizations ( Figure S6 ), confirming that no aggregation of Pt NPs occurred during recycling process. Conclusion In summary, Pt/TiO 2 was found to be a superior catalyst for BA hydrogenation in comparison with Ru/C and Pd/C due to the weak interaction strength between Pt and BA which inhibited the toxic of BA to the catalyst. A record TOF of 4490 h -1 was achieved with Pt/TiO 2 under 80 o C and 50 bar H 2 in hexane, more than 10 times higher than the literature results under similar conditions. Isotopic studies confirmed that the dissociated hydrogen from the carboxyl group was involved in BA hydrogenation which could be facilitated by the strong adsorption of BA on Pt surface. By comparing the activity of Pt/TiO 2 catalysts with different surface electronic and geometric structures, it could be concluded that electron deficient and low coordination Pt sites had higher catalytic activity than electron rich and high coordination Pt sites in BA hydrogenation, possibly due to the combined effect of higher H 2 activation ability and the stronger adsorption of BA by electron deficient Pt sites. The wide substrate scope including e.g. very challenging terephthalic acid, phthalate acid, phthalic acid, iso-phthalic and trimesic acid demonstrates the potential practical applications of Pt/TiO 2 in hydrogenation of BA and its derivatives. Experimental Section Chemicals and Materials The chemicals were purchased from commercial suppliers and used as received with details listed below: 4-methylbenzoic acid (98%, Innochem (Beijing) chemicals), anisic acid (98%), benzamide (98%), cyclohex-1-ene-1-carboxylic acid (97%) were from ARK Chemicals. dioctyl phthalate (99%), phthalic acid (98%), 4-ethylbenzoic acid (98%), 4-isopropylbenzoic acid (98%) and 4-amylbenzoic acid (98%) were from Aladdin (Shanghai) chemicals. 4-Hydroxybenzoic acid (99%), 2-methylbenzoic acid (98%) and 3-methylbenzoic acid (98%) were from TCI (Shanghai) chemicals. Benzoic-2, 3, 4, 5, 6-d 5 acid (≥99 atom % D) was purchased from Macklin Chemicals. Chloroplantinic acid (H 2 PtCl 6 ), toluene and other reagents were purchased from Sinopharm Chemical Reagent Co., Ltd. TiO 2 (Rutile, 25-30 nm) was bought from Aladdin (Shanghai) chemicals. Fumed silica (SiO 2 ) and Pt/C (5%) were respectively from Sigma-Aldrich and TCI chemicals. Catalyst Preparation Preparation of the Pt/TiO 2 Catalyst Pt catalysts with Pt loading of 2 wt% were prepared by the deposition precipitation method using NaBH 4 as the reactant [34, 58]. Typically, 200 mg of TiO 2 and the desired amount of H 2 PtCl 6 (4 mg Pt) was initially dispersed into 50 mL of aqueous solution. After stirring for 1 h at room temperature, a freshly prepared NaBH 4 aqueous solution (2.3 mg, 0.2 mg mL -1 ) was added slowly. After stirring for another 1 h, the solid was collected by filtration and washed with water and ethanol for three times. Finally, the obtained powder was dried at room temperature overnight. The catalyst was denoted as Pt/TiO 2 . Preparation of the Pt/TiO 2 -200 and Pt/TiO 2 -450 Catalyst Pt/TiO 2 was treated in a H 2 atmosphere with a flow rate of 20 mL min -1 at the desired temperature for 2 h with a heating rate of 1 o C min -1 . The sample after treatment was denoted as Pt/TiO 2 -T, where T (200 and 450) refers to the treatment temperature. Synthesis of Other Oxide Support Loaded Pt Catalyst Pt/SiO 2 with Pt loading of 2 wt% was prepared by the wet impregnation method by dispersing SiO 2 (200 mg) in 2 mL of aqueous solution of H 2 PtCl 6 (4 mg Pt) for 5 h. Then the solid product after drying by an evaporator and reduced under H 2 atmosphere at 300 °C for 2 h to afford Pt/SiO 2 . Other oxide supported Pt catalysts were prepared with a similar method to Pt/TiO 2 except that the corresponding oxide was used as supports. Analysis by inductively couple plasma atomic emission analysis (ICP-AES) clearly indicated that the desired amounts of metal species were successfully loaded onto each of the catalysts. Characterization Transmission electron microscopy (TEM) image were obtained using a HITACHI HT7700 at an acceleration voltage of 100 kV. High-resolution scanning electron microscopy (HRSEM) was undertaken by using a HITACHI S5500 apparatus operating at an acceleration voltage of 1-30 kV. X-ray photoelectron (XPS) was performed on an ESCALAB 250xi spectrometer using Al Kα radiation. All the XPS spectra were calibrated by the C1s peak (284.6 eV) from contamination to compensate the charge effects. N 2 sorption isotherms were carried out on a Micromeritics ASAP2020 volumetric adsorption analyzer. Liquid 1 H and 13 C, NMR spectra were recorded on a Bruker Avance 400 MHz spectrometer at 25 °C. In situ diffuse reflectance infrared Fourier transform spectra (DRIFTS) of CO chemisorption was measured on a Thermo Scientific IR spectrometer with a mercury cadmium telluride (MCT) detector, recorded with a resolution of 4 cm −1 [59]. Prior to CO adsorption, the samples were treated in situ in the DRIFT cell under a H 2 flow (20 mL min −1 ) at the desired temperatures for 1 h, followed by purging with a He flow at the same temperature for 30 min. After cooling to room temperature, a background spectrum was collected. Then the He flow was switched to a pure CO flow (20 mL min −1 ) until saturated adsorption was achieved. CO adsorption experiments were carried out sequentially on a single sample. Gas-phase CO spectra were collected at the same pressure and subtracted from the corresponding sample spectra. CO/H 2 chemisorption measurement was performed at 50 °C on a Autochem II 2920 chemisorption instrument with a thermal conductivity detector (TCD). The sample (~100 mg) was pretreated with hydrogen at desired temperatures for 1 h, followed by purging with high-purity He (or Ar) for 30 min. After the sample was cooled down to 50 °C, a 5% CO/He (or 10% H 2 /Ar) mixture was injected into the reactor repeatedly until CO (or H 2 ) adsorption was saturated. The dispersion of Pt was calculated from the amount of CO adsorbed by assuming the CO/Pt adsorption stoichiometry to be 1/1. H 2 −D 2 exchange reactions were carried out in a flow quartz reactor at 22 °C [60]. The formation rate of HD was measured by mass signal intensity (ion current). Before the test, the catalysts were heated in H 2 (10 mL min −1 ) at 200 °C for 20 min. After the sample was cooled down to room temperature, D 2 (10 mL min −1 ) mixed with H 2 was passed through the sample. The gas hourly space velocity (GHSV) is 2.9 × 10 7 mL h −1 g metal −1 . Under these conditions, the H 2 −D 2 exchange conversions were always kept below 15% for calculation of turnover frequency (TOF) [61]. Products (HD, H 2 , and D 2 ) were analysed with an online mass spectrometer (GAM200, InProcess Instruments). The mass/charge ratio (m/z) values used are 2 for H 2 , 4 for D 2 , and 3 for HD. The background HD exchanges from the corresponding support were deducted from the results. General Procedure for the Hydrogenation of Benzoic Acid (BA). The hydrogenation reactions were carried out in a stainless steel autoclave (300 mL) with a thermocouple-probed detector. In a typical process for benzoic acid (BA) hydrogenation, a desired amount of the solid catalyst was placed in an ampule tube, followed by the addition of BA (0.12 mmol) and 3 mL of n-hexane (for reaction performed at S/C of 1200, 0.3 mL of acetic acid was added to assist the dissolution of BA). The ampule tube was loaded into the reactor. After the tube was purged six times with hydrogen, the final pressure was adjusted to 10 bar and the reactor was heated to desired temperature with vigorous stirring. After the reaction, the solid catalyst was separated by centrifugation and the filtrate was collected, diluted with n-hexane, and analyzed by an Agilent 6890N GC instrument equipped with an Agilent J&W GC HP-INNOWax capillary column (30 m × 0.32 mm × 0.25 μm). The diphenyl ether was used as the internal standard to determine the conversion, selectivity and carbon balance. The carbon balance was ~ 100%. For the recycle experiments, the liquid was decanted after centrifugation of the reaction mixture. The residual catalyst was thoroughly washed with n-hexane, and used directly for the next run. Computational Setup All the calculations were performed with density functional theory (DFT) by using the Vienna Ab-initio Simulation Package (VASP) [62,63]. The projector augmented-wave pseudopotential method with Perdew-Burke-Ernzerhof (PBE) exchange-correlation functional including zero-damping DFT-D3 of Grimme’s correction was employed [64,65]. A plane-wave basis with cutoff energy of 400 eV was adopted. Four-atomic-layer slab models of Pt(111), Pd(111), and Ru(0001) with the bottom two layers fixed consisting of 144 metal atoms were built. The vacuum spaces were set as 15 Å between the layers. A gamma k-point sampling of 1×1×1 was selected. The convergence energy and force were set to be 1 × 10 −5 eV and 0.02 eV/Å, respectively. The adsorption energy E ad was calculated as: E ad = E ad/sub − E mol − E sub The E ads/sub , E mol and E sub are the total energy of the adsorbed molecule, the molecule in the gas phase, and the pure slab, respectively. Declarations ACKNOWLEDGMENTS We acknowledge financial support from the National Key R&D Program of China (2017YFB0702800), the National Natural Science Foundation of China (21733009), and the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB17020200). AUTHOR CONTRIBUTIONS Q. H. Y. conceived the idea. Q. H. Y., M. G., X. T. K. and C. Z. L. co-wrote the paper. M. G. synthesized the nanomaterials and carried out the catalysis experiments. X. T. K. carried out the model construction and DFT calculations. C. Z. L. analyzed part of NMR results. All the authors contributed to the overall scientific interpretation and edited the manuscript. References [1] B. S. Moore, H. Cho, R. Casati, E. Kennedy, K. A. Reynolds, U. Mocek, J. M. Beale, H. G. 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Krieg, A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu. J. Chem. Phys., 132 (2010) 154104–19. Additional Declarations There is NO Competing Interest. Supplementary Files SI.docx Cite Share Download PDF Status: Published Journal Publication published 16 Apr, 2021 Read the published version in Communications Chemistry → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-108586","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":5710627,"identity":"6144763a-539f-4658-b72d-1979519102dc","order_by":0,"name":"Miao Guo","email":"","orcid":"","institution":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Miao","middleName":"","lastName":"Guo","suffix":""},{"id":5710628,"identity":"87215e3f-1236-46d0-8825-f4a01bc9d3d0","order_by":1,"name":"Xiangtao Kong","email":"","orcid":"","institution":"Anyang Normal University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Xiangtao","middleName":"","lastName":"Kong","suffix":""},{"id":5710629,"identity":"493f9fdd-42f4-4481-a480-c2d68a49dd68","order_by":2,"name":"Chunzhi Li","email":"","orcid":"","institution":"Dalian Institute of Chemical Physics","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Chunzhi","middleName":"","lastName":"Li","suffix":""},{"id":5710630,"identity":"07f1d3f1-212b-4431-acf0-470873a83ed6","order_by":3,"name":"Qihua Yang","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAxUlEQVRIiWNgGAWjYLACxgYbxjZStaSRruUwYwPRqg2Onz384u2O87J97GcPMPyoYZA3J6jlTF6a5dwzt43bePISGHuOMRjuJGSfwYEcM2PettuJbRI8Bgy8DQwJBgcIaTn/BqTlHFgL41+itNzIMX7M23YArIWZKFskb7wxY5zblgz2y2GZYxKGGwhp4TufY/zhbZud7Pz2swcfvqmxkSdoi8IBBjYJHjCThwGoWIKAeiCQb2Bg/gDTMgpGwSgYBaMAKwAAr0xCp/KxQBkAAAAASUVORK5CYII=","orcid":"https://orcid.org/0000-0002-1118-3397","institution":"Dalian Institute of Chemical Physics","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Qihua","middleName":"","lastName":"Yang","suffix":""}],"badges":[],"createdAt":"2020-11-15 04:05:32","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-108586/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-108586/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1038/s42004-021-00489-z","type":"published","date":"2021-04-16T04:00:00+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":4017541,"identity":"d5989582-03c3-4d45-aff7-3192374da8ec","added_by":"auto","created_at":"2020-12-04 15:15:28","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":53120,"visible":true,"origin":"","legend":"(a) The catalytic results of supported metal NPs for BA hydrogenation in hexane (40 oC, 10 bar H2, S/C of 700, 2 h). (b) Adsorption energies of BA and acetic acid on Pt (111), Pd (111) and Ru (0001) obtained by DFT calculations.","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/8aa9f447c7e52780bb1544c7.png"},{"id":4017543,"identity":"0d8d65c1-007e-4f2d-a744-c60a67ab586b","added_by":"auto","created_at":"2020-12-04 15:15:29","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":551553,"visible":true,"origin":"","legend":"(a) HRSEM image and (b) HAADF-STEM image of Pt/TiO2 (scale bar 50 nm). (c) Pt 4f XPS core level spectra and (d) CO DRIFTS results for (i) Pt/TiO2, (ii) Pt/TiO2-200 and (iii) Pt/TiO2-450. The inset in panel a shows particle size distribution of Pt/TiO2.","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/be02e19bc03298c9919049d0.png"},{"id":4017544,"identity":"036b5c41-fafe-4141-946e-4bcb9ee38d4a","added_by":"auto","created_at":"2020-12-04 15:15:29","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":111749,"visible":true,"origin":"","legend":"Reaction orders with respective to (a) BA and (b) H2, (c) Arrhenius plots showing apparent activation barriers, and (d) H2-D2 exchange results of (i) Pt/TiO2 and (ii) Pt/TiO2-450. Reaction conditions for (a) and (b): 3 mL n-hexane, H2 pressure: 1 - 40 bar, BA concentration: ~3 - ~ 10 mg/mL, 40 oC for Pt/TiO2, 60 oC for Pt/TiO2-450. Reaction conditions for (c): T = 30-70 oC, S/C=250, 3 mL hexane. The BA conversion was maintained ~ 10 – ~20 % by adjusting reaction time.","description":"","filename":"3.png","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/b9d0cae20410d6e082d6cfe5.png"},{"id":4017545,"identity":"af5c9989-137c-4214-b715-fca86aecb4ad","added_by":"auto","created_at":"2020-12-04 15:15:30","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":403339,"visible":true,"origin":"","legend":" (a) Comparison of the catalytic activity of Pt/TiO2 in hydrogenation of benzotrifluoride, toluene and BA. (b) The adsorption mode of (i) BA and (ii) toluene on Pt (111). (c) 1H-NMR (i) and MS analysis (ii) of the product for benzoic-d5 acid hydrogenation with D2. (d) Recycling stability of Pt/TiO2 in the hydrogenation of BA.","description":"","filename":"4.png","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/61e4fb283038ab52e69de489.png"},{"id":15783728,"identity":"f17f1401-8ae0-4bea-a570-ecdb3f5b66e0","added_by":"auto","created_at":"2021-11-22 15:49:02","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1513397,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/92f21da3-ad5f-4ba5-ace2-42c4705b901a.pdf"},{"id":4017542,"identity":"d3a6faa7-6652-4d3d-9aa6-34090e532d7f","added_by":"auto","created_at":"2020-12-04 15:15:29","extension":"docx","order_by":1,"title":"","display":"","copyAsset":false,"role":"supplement","size":19861695,"visible":true,"origin":"","legend":"","description":"","filename":"SI.docx","url":"https://assets-eu.researchsquare.com/files/rs-108586/v1/2bf18d41cb4fb591c6e2ab69.docx"}],"financialInterests":"There is \u003cb\u003eNO\u003c/b\u003e Competing Interest.","formattedTitle":"Pt/TiO2 Catalyzed Hydrogenation of Benzoic Acid with Unprecedented High Activity","fulltext":[{"header":"Introduction","content":"\u003cp\u003eThe selective hydrogenation of benzoic acid (BA) or its derivatives has been widely used for the production of fine chemicals, intermediates and industrial raw materials [1-3]. For example, BA hydrogenation to cyclohexanecarboxylic acid (CCA) is an important step in the production of nylon-6 in industry [4-5]. However, the need to overcome the high resonance energy of the electron deficient aromatic ring [6] and the catalyst \u0026ldquo;poison\u0026rdquo; by carboxyl group [7,8] make BA hydrogenation as one of the most challenging transformations. Harsh conditions (100~250 \u003csup\u003eo\u003c/sup\u003eC, 50~150 bar H\u003csub\u003e2\u003c/sub\u003e) are typically required in order to obtain high BA conversion, which inevitably causes the decrease in selectivity due to the side reactions of decarboxylation and over hydrogenation [9,10]. Up to now, various supported metal catalysts (e.g. Pd, Ru, Rh, and Ni) have been used for BA hydrogenation under relatively mild conditions, but the activity is still relatively low [11,12].\u003c/p\u003e\n\u003cp\u003ePrevious results demonstrated that most of the supported metal catalysts were active only with water as solvent under mild condition and showed low or no activity in organic solvents for BA hydrogenation [13]. The typical solvation effect is possibly related with the preferential adsorption of aromatic ring on metal surface induced by the interaction of carboxyl group with H\u003csub\u003e2\u003c/sub\u003eO molecules [13,14] and the participation of H* from the dissociated H\u003csub\u003e2\u003c/sub\u003eO molecules in the reaction [2,15]. Though water could modify the adsorption mode of substrates, it may also block the surface active sites [16,17]. Taken together the low H\u003csub\u003e2\u003c/sub\u003e solubility in water (e.g. 0.792 mmol L\u003csup\u003e-1\u003c/sup\u003e, 298.15 K, 1 atm H\u003csub\u003e2\u003c/sub\u003e) [18], water is not a good choice for efficient BA hydrogenation under mild conditions.\u003c/p\u003e\n\u003cp\u003eCarboxylates tend to strongly adsorb on metal surface, which significantly deteriorates the catalytic activity through so-called \u0026ldquo;poison effects\u0026rdquo; [19]. In contrast, the adsorption of aromatic ring of BA on metal surface is weak considering that the electron deficient phenyl ring does not easily bind to the surface unoccupied \u003cem\u003ed\u003c/em\u003e-metal orbitals via \u0026pi;-bonds [20,21]. This may be the reason that most metal NPs showed relatively low activity in BA hydrogenation. Recently, our group reported that the activity of Ru NPs was greatly enhanced in BA hydrogenation by tuning the adsorption mode of BA on metal surface with phosphine ligands [2]. Therefore, to realize the efficient BA hydrogenation, the supported metal NPs with appropriate adsorption strength towards carboxyl group and aromatic ring may be the good choice.\u003c/p\u003e\n\u003cp\u003eHerein, we reported that Pt/TiO\u003csub\u003e2\u003c/sub\u003e is a highly active and selective catalyst for BA hydrogenation under mild conditions in either organic solvents or water by screening a series of supported metal NPs. Pt/TiO\u003csub\u003e2\u003c/sub\u003e gives a record activity with apparent TOF up to 4490 h\u003csup\u003e-1\u003c/sup\u003e under 80 \u003csup\u003eo\u003c/sup\u003eC and 50 bar H\u003csub\u003e2\u003c/sub\u003e in hexane. The studies indicated that electron deficient Pt sites were more active than electron rich Pt sites, possibly due to the facilitated participation of H from carboxyl group in BA hydrogenation on electron deficient Pt sites.\u003c/p\u003e"},{"header":"Results And Discussion","content":"\u003cp\u003e\u003cstrong\u003eScreening the Supported Metal NPs for BA Hydrogenation\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFirstly, commercially available carbon supported metal NPs were tested in BA hydrogenation (\u003cstrong\u003eFigure 1a\u003c/strong\u003e). Pd/C (5 wt%) and Ru/C (5 wt%) were almost inactive in hexane at 40 \u0026deg;C and 10 bar H\u003csub\u003e2\u003c/sub\u003e, similar to previous report [13, 22]. To our delight, Pt/C (5 wt%) afforded 51% conversion with \u0026gt; 99% selectivity to CCA under identical conditions. Inspired by this result, different types of supported Pt catalysts with Pt loading of 2 wt% were screened in BA hydrogenation (\u003cstrong\u003eFigure 1a\u003c/strong\u003e) considering that the support with different acid/base or redox properties may influence the catalytic performance of supported metal NPs [23,24]. Pt/MgO, Pt/CeO\u003csub\u003e2\u003c/sub\u003e, Pt/CN and Pt/\u0026gamma;-Al\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e3 \u003c/sub\u003eafforded less than 20% BA conversion. Pt/SiO\u003csub\u003e2\u003c/sub\u003e and Pt/ZrO\u003csub\u003e2\u003c/sub\u003e gave moderate BA conversion respectively of 65% and 35%. Pt/TiO\u003csub\u003e2\u003c/sub\u003e afforded high BA conversion of 96% with \u0026gt; 99% selectivity to CCA. The catalyst screen results suggest that the base and acid support respectively deteriorate [25] and promote [26] the aromatic hydrogenation activity of Pt in BA hydrogenation. Even at 25 \u003csup\u003eo\u003c/sup\u003eC and 1 bar H\u003csub\u003e2\u003c/sub\u003e, Pt/TiO\u003csub\u003e2\u003c/sub\u003e could still afforded \u0026gt; 99% BA conversion and CCA selectivity (\u003cstrong\u003eTable 1\u003c/strong\u003e). The apparent TOF of Pt/TiO\u003csub\u003e2\u003c/sub\u003e was calculated to be 115 h\u003csup\u003e-1\u003c/sup\u003e at 25 \u003csup\u003eo\u003c/sup\u003eC, 1 bar H\u003csub\u003e2\u003c/sub\u003e and 638 h\u003csup\u003e-1\u003c/sup\u003e at 40 \u003csup\u003eo\u003c/sup\u003eC, 10 bar H\u003csub\u003e2\u003c/sub\u003e. To increase S/C ratio is very important for practical applications. Thus, the BA hydrogenation was performed at S/C as high as 1200 over Pt/TiO\u003csub\u003e2\u003c/sub\u003e in the presence of acetic acid to facilitate the dissolution of BA in hexane. Under such harsh conditions, Pt/TiO\u003csub\u003e2\u003c/sub\u003e could still afford 90% conversion with the apparent TOF of 4490 h\u003csup\u003e-1\u003c/sup\u003e at 80 \u0026deg;C and 50 bar H\u003csub\u003e2\u003c/sub\u003e, an order of magnitude higher than the supported metal NPs ever reported (\u003cstrong\u003eTable S1\u003c/strong\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 1\u003c/strong\u003e. The catalytic performance of Pt/TiO\u003csub\u003e2\u003c/sub\u003e catalysts in the hydrogenation of BA.\u003csup\u003ea\u003c/sup\u003e\u003c/p\u003e\u003cp\u003e\u003cimg 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\"\u003e\u003c/p\u003e\n\u003cp\u003e\u003csup\u003ea\u003c/sup\u003eReaction conditions: 40 \u003csup\u003eo\u003c/sup\u003eC, 10 bar H\u003csub\u003e2\u003c/sub\u003e, 1 h. \u003csup\u003eb\u003c/sup\u003eSelectivity to CCA. Only less than 5% cyclohexenecarboxylic acid (CEA) was detected as the intermediate during the reaction process. \u003csup\u003ec\u003c/sup\u003eApparent TOF is calculated as moles of converted BA per mole of Pt per hour with the conversion less than 30%. The values in parentheses were the TOF calculated based on Pt dispersion. \u003csup\u003ed\u003c/sup\u003e25 \u003csup\u003eo\u003c/sup\u003eC, 1 bar H\u003csub\u003e2\u003c/sub\u003e, 3 h. \u003csup\u003ee\u003c/sup\u003e80 \u003csup\u003eo\u003c/sup\u003eC, 50 bar H\u003csub\u003e2\u003c/sub\u003e, 1.5 h.\u003c/p\u003e\n\u003cp\u003eThe catalyst screen results suggest that Pt NPs are active for BA hydrogenation in hexane irrespective of the supports, different from Pd and Ru NPs. Density functional theory (DFT) calculation showed that the adsorption energies of BA on Pt (111), Pd (111) and Ru (1000) is respectively of -1.53 eV, -2.87 eV and -2.95 eV, showing the stronger adsorption of BA on Ru and Pd than on Pt and the adsorption energies of acetic acid on Pt (111), Pd (111) and Ru (1000) gave similar tendency (\u003cstrong\u003eFigure 1b\u003c/strong\u003e). This suggests that the relative weak adsorption strength of BA on Pt may contribute to the high activity of Pt NPs in BA hydrogenation.\u003c/p\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e was active in hexane, H\u003csub\u003e2\u003c/sub\u003eO, cyclohexane, isopropyl alcohol and EtOH (\u003cstrong\u003eTables 1 and S2\u003c/strong\u003e), showing the wide solvent tolerance. Even using acetic acid as the solvent, 68% conversion could still be obtained, showing the high anti-carboxyl poisoning ability of Pt NPs. The product selectivity to CCA is \u0026gt; 93% for all the solvents investigated with cyclohexenecarboxylic acid as the side product. BA conversion in aprotic and oxygenate free solvents (e.g. n-hexane) is much higher than that in protic and oxygenate solvents. The decreased hydrogenation rate may be related to the hydrogen bonding of protic solvent and BA, which may hinder the BA adsorption on Pt surface [27]. It is noteworthy to mention that the activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e was much lower in water than in hexane, which is possibly related with the active sites blocking and low solubility of H\u003csub\u003e2\u003c/sub\u003e in water [16, 18, 28].\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Influence of Electronic and Geometric Structures of Pt on BA Hydrogenation\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 were prepared by treatment of Pt/TiO\u003csub\u003e2\u003c/sub\u003e under H\u003csub\u003e2\u003c/sub\u003e atmosphere at 200 and 450 \u003csup\u003eo\u003c/sup\u003eC, respectively. The TEM, HRSEM and HAADF-STEM images of Pt/TiO\u003csub\u003e2\u003c/sub\u003e, Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 showed the uniform distribution of Pt with particle size of 2.9 nm, showing that no aggregation of Pt NPs occurred during the H\u003csub\u003e2\u003c/sub\u003e treatment process (\u003cstrong\u003eFigures 2, S1-S3\u003c/strong\u003e). The CO chemisorption results showed that Pt dispersion for Pt/TiO\u003csub\u003e2\u003c/sub\u003e, Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 was respectively of 29.0, 22.6 and 24.2 (\u003cstrong\u003eTable 2\u003c/strong\u003e). The Pt dispersion of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 slightly decreased, which may be caused by the weak adsorption ability of CO at the interface of Pt and TiO\u003csub\u003e2\u003c/sub\u003e after H\u003csub\u003e2\u003c/sub\u003e treatment [29]. The Pt dispersion obtained by H\u003csub\u003e2\u003c/sub\u003e molecules was almost the same for Pt/TiO\u003csub\u003e2\u003c/sub\u003e, Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 (\u003cstrong\u003eTable 2\u003c/strong\u003e). It should be noted that the Pt dispersion of Pt/TiO\u003csub\u003e2\u003c/sub\u003e before and after H\u003csub\u003e2\u003c/sub\u003e treatment was comparable, showing that the H\u003csub\u003e2\u003c/sub\u003e treatment of Pt/TiO\u003csub\u003e2\u003c/sub\u003e did not induce the severe coverage of Pt surface by TiO\u003csub\u003ex\u003c/sub\u003e, which may be due to pre-nucleation reduction method for the synthesis of the parent Pt/TiO\u003csub\u003e2 \u003c/sub\u003e[30,31].\u003c/p\u003e\n\u003cp\u003eThe reaction profiles for BA hydrogenation displayed that more BA was converted to CCA with Pt/TiO\u003csub\u003e2\u003c/sub\u003e than with Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 within the same reaction time (\u003cstrong\u003eFigure S4\u003c/strong\u003e). Under similar conditions, Pt/TiO\u003csub\u003e2\u003c/sub\u003e with \u0026gt; 99% conversion was more active than Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 with conversion respectively of 59% and 10% (\u003cstrong\u003eTable 1\u003c/strong\u003e). To make reasonable comparisons, the TOF of Pt/TiO\u003csub\u003e2\u003c/sub\u003e catalysts was normalized to Pt dispersion obtained with CO chemisorption. Pt/TiO\u003csub\u003e2\u003c/sub\u003e, Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 respectively afforded TOF of 2200 h\u003csup\u003e-1\u003c/sup\u003e, 757 h\u003csup\u003e-1\u003c/sup\u003e and 103 h\u003csup\u003e-1\u003c/sup\u003e, further confirming that Pt/TiO\u003csub\u003e2\u003c/sub\u003e is more active than Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450.\u003c/p\u003e\n\u003cp\u003eGenerally, the H\u003csub\u003e2\u003c/sub\u003e treatment of Pt/TiO\u003csub\u003e2\u003c/sub\u003e at high temperature would induce the change in electronic and geometric structure of Pt due to the strong metal-support interaction (SMSI) [32]. In order to understand the different catalytic properties of Pt/TiO\u003csub\u003e2 \u003c/sub\u003ecatalysts, the electronic structure of Pt was firstly characterized by X-ray photoelectron spectroscopy (XPS) (\u003cstrong\u003eFigure 2c, Table 2)\u003c/strong\u003e. Compared with Pt/TiO\u003csub\u003e2\u003c/sub\u003e, Pt 4f binding energies (BEs) of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 showed an obvious downward shift respectively by 0.3 eV and 0.4 eV, suggesting that Pt/TiO\u003csub\u003e2\u003c/sub\u003e had more electron deficient Pt sites than Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450. The decrease in Pt 4f BEs indicates the charge transfer from Ti cations to Pt NPs induced by SMSI [33], which was further confirmed by the higher Ti 2p\u003csub\u003e3/2\u003c/sub\u003e BEs of Pt/TiO\u003csub\u003e2 \u003c/sub\u003ethan those of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 (\u003cstrong\u003eFigure S5\u003c/strong\u003e). It should be noted that Ti 2p\u003csub\u003e3/2\u003c/sub\u003e BEs of Pt/TiO\u003csub\u003e2\u003c/sub\u003e were lower than those of TiO\u003csub\u003e2\u003c/sub\u003e, implying the electron transfer from Pt to Ti cations. The Pt\u003csup\u003e0\u003c/sup\u003e/Pt\u003csup\u003e\u0026delta;+\u003c/sup\u003e ratio of Pt/TiO\u003csub\u003e2\u003c/sub\u003e increased from 68/32 to 74/26 after heat treatment in H\u003csub\u003e2\u003c/sub\u003e, showing that the reduction degree of Pt increased at high temperature (\u003cstrong\u003eTable 2\u003c/strong\u003e). The electronic structure of Pt/TiO\u003csub\u003e2\u003c/sub\u003e catalysts could be facilely modified due to the electron-withdrawing ability of acidic TiO\u003csub\u003e2\u003c/sub\u003e support [34] and the SMSI effect of Pt-TiO\u003csub\u003e2\u003c/sub\u003e system [35].\u003c/p\u003e\n\u003cp\u003eThe electronic and geometric structures of Pt NPs were further characterized with in situ diffuse reflectance infrared Fourier transform spectra (DRIFTS) of CO chemisorption (\u003cstrong\u003eFigure 2d\u003c/strong\u003e). DRIFTS of adsorbed CO for Pt/TiO\u003csub\u003e2\u003c/sub\u003e showed four distinct \u0026upsilon;\u003csub\u003eCO\u003c/sub\u003e bands in the linear carbonyl region located at approximately 2115, 2096, 2079 and 2062 cm\u003csup\u003e-1\u003c/sup\u003e. The band at 2115 cm\u003csup\u003e-1\u003c/sup\u003e can be assigned to Pt\u003csup\u003e\u0026delta;+\u003c/sup\u003e [36]. The lower frequency vibrational stretch at 2062 cm\u003csup\u003e-1\u003c/sup\u003e was assigned to CO molecules adsorbed on low-coordination Pt-edge and -corner sites. The higher frequency vibrational stretch at 2096 and 2079 cm\u003csup\u003e\u0026minus;1\u003c/sup\u003e can be assigned to CO molecules that are adsorbed on the Pt (111) terrace sites (the coordination number of 9) and Pt (110) (the coordination number of 8), respectively [37-42]. The DRIFTS of adsorbed CO for Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 was similar to that of Pt/TiO\u003csub\u003e2\u003c/sub\u003e with the exception that the red shift of the vibration peaks was observed, showing the electron donation from Ti cations to Pt due to SMSI effect. The lower activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 than Pt/TiO\u003csub\u003e2\u003c/sub\u003e suggested that Pt with electron deficient surface was favorable for the BA hydrogenation considering that the two catalysts had similar geometric surface structure of Pt.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 2\u003c/strong\u003e. Pt dispersion measured with H\u003csub\u003e2\u003c/sub\u003e/CO chemisorption, Pt 4f and Ti 2p binding energies by XPS of Pt catalysts.\u003c/p\u003e\n\u003ctable border=\"1\" width=\"503\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"87\"\u003e\n\u003cp\u003eCat.\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003ePt dispersion (%) \u003csup\u003ea\u003c/sup\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003ePt dispersion (%) \u003csup\u003eb\u003c/sup\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003eTi 2p\u003csub\u003e3/2\u003c/sub\u003e (eV) \u003csup\u003ec\u003c/sup\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003ePt 4f\u003csub\u003e7/2\u003c/sub\u003e (eV) \u003csup\u003ec\u003c/sup\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003ePt\u003csup\u003e0\u003c/sup\u003e/Pt\u003csup\u003e+\u003c/sup\u003e (%) \u003csup\u003ec\u003c/sup\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"87\"\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e29.0\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e48.4\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e458.4\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e71.1\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e68/32\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"87\"\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e-200\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e22.6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e49.6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e458.6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e70.8\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e70/30\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"87\"\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e-450\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e24.2\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e44.6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e458.6\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e70.7\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e74/26\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"87\"\u003e\n\u003cp\u003eTiO\u003csub\u003e2\u003c/sub\u003e\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e--\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"94\"\u003e\n\u003cp\u003e--\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e458.5\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e--\u003c/p\u003e\n\u003c/td\u003e\n\u003ctd width=\"76\"\u003e\n\u003cp\u003e--\u003c/p\u003e\n\u003c/td\u003e\n\u003c/tr\u003e\n\u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003csup\u003ea\u003c/sup\u003eData calculated from CO chemisorption results. \u003csup\u003eb\u003c/sup\u003eData calculated from H\u003csub\u003e2\u003c/sub\u003e chemisorption results. \u003csup\u003ec\u003c/sup\u003eData obtained from XPS results.\u003c/p\u003e\n\u003cp\u003eThe DRIFTS of adsorbed CO for Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 is quite different from those of Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200. The obvious change in peak intensities of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 suggested the reconstruction of surface Pt atoms under high temperature H\u003csub\u003e2\u003c/sub\u003e treatment [39]. The relatively high peak intensity at 2083 cm\u003csup\u003e-1\u003c/sup\u003e indicated that Pt surface had more well-ordered Pt surface (111). The peak assigned to Pt (111) gradually red shifted with H\u003csub\u003e2\u003c/sub\u003e treatment temperature increasing, implying the TiO\u003csub\u003e2\u003c/sub\u003e donates more electrons to Pt at higher temperature [43]. In comparison with Pt/TiO\u003csub\u003e2 \u003c/sub\u003eand Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200, the much lower activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 indicated that the electron deficient and low coordination Pt sites may be active for BA hydrogenation. \u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eThe reaction order of BA and H\u003csub\u003e2\u003c/sub\u003e was investigated with Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 as representative catalysts considering that the reaction kinetics are particularly sensitive to the active Pt structure (\u003cstrong\u003eFigures 3a, 3b) \u003c/strong\u003e[44,45]. The order of BA hydrogenation with respect to BA is respectively of -0.29, and 0.45 for Pt/TiO\u003csub\u003e2\u003c/sub\u003e, and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450, implying the stronger adsorption of BA on Pt/TiO\u003csub\u003e2\u003c/sub\u003e than on Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450. The reaction rate of Pt/TiO\u003csub\u003e2\u003c/sub\u003e increased along with the H\u003csub\u003e2\u003c/sub\u003e pressure and no plateau was observed with H\u003csub\u003e2\u003c/sub\u003e pressure range of 6 to 40 bar, which was possibly related with the strong adsorption of BA. The reaction order with respective to H\u003csub\u003e2\u003c/sub\u003e for Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 is +0.50 and ~0, respectively. The positive order in hydrogen for the BA hydrogenation is a logical consequence of hydrogenation being involved in rate-determining step. The kinetic results showed that the overall reaction order of BA hydrogenation on Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 is much larger than that on Pt/TiO\u003csub\u003e2\u003c/sub\u003e (+0.46 vs. +0.25, \u003cstrong\u003eTable S3\u003c/strong\u003e), indicating different reaction mechanism for the two catalysts. Temperature dependent reactivity measurements were taken to obtain apparent activation barriers with Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 as representative (\u003cstrong\u003eFigure 3c\u003c/strong\u003e). The activation energies for Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 were respectively of ~38 kJ mol\u003csup\u003e-1\u003c/sup\u003e and ~56 kJ mol\u003csup\u003e-1\u003c/sup\u003e, showing the two catalysts have different catalytic sites for BA hydrogenation [46-48]. The higher energy barriers of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 explains its low activity in BA hydrogenation.\u003c/p\u003e\n\u003cp\u003eThe characterization data showed that the electron density of Pt NPs followed the order of Pt/TiO\u003csub\u003e2\u003c/sub\u003e \u0026lt; Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 \u0026lt; Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450. In combination with the catalytic activity, we can infer that the electronic deficient Pt may favor the high BA hydrogenation. From kinetic data, Pt/TiO\u003csub\u003e2\u003c/sub\u003e and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 had strong and weak adsorption towards BA, implying that electron rich Pt had weaker adsorption for BA. According to the Sabatier rule, too strong or too weak adsorption of reactants on catalysts does not favor high activity. The minus reaction order of BA over Pt/TiO\u003csub\u003e2\u003c/sub\u003e means that BA (or CCA) in fact is \u0026ldquo;a poison\u0026rdquo; for the catalyst, which blocked the active sites.\u003csup\u003e49\u003c/sup\u003e The higher reaction order of H\u003csub\u003e2\u003c/sub\u003e over Pt/TiO\u003csub\u003e2\u003c/sub\u003e than over Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 indicated that H\u003csub\u003e2\u003c/sub\u003e adsorption is relative more difficult for the former sample due to the strong BA adsorption. But Pt/TiO\u003csub\u003e2\u003c/sub\u003e still showed much higher activity than Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450, suggesting that the H\u003csub\u003e2\u003c/sub\u003e activation played an important role in BA hydrogenation. The H\u003csub\u003e2\u003c/sub\u003e activation ability of the catalysts was measured using H\u003csub\u003e2\u003c/sub\u003e-D\u003csub\u003e2\u003c/sub\u003e exchange experiments (\u003cstrong\u003eFigure 3d, Table S4\u003c/strong\u003e). The normalized HD formation rate of Pt/TiO\u003csub\u003e2\u003c/sub\u003e is more than 10 fold that of Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450, showing that Pt/TiO\u003csub\u003e2\u003c/sub\u003e with electronic deficient Pt surface is more active for H\u003csub\u003e2\u003c/sub\u003e activation than Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 with electronic rich Pt surface. This result suggests that the high activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e is partly attributed to the high H\u003csub\u003e2\u003c/sub\u003e activation ability.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Role of the Carboxyl Group\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eGenerally, the deficient phenyl ring does not easily bond on metal surface [20], which always results in low catalytic activity [50]. However, the high activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e in BA hydrogenation suggests that carboxyl group may affect the hydrogenation activity. To identify the role of carboxyl group in BA hydrogenation, hydrogenation of benzotrifluoride and toluene were conducted (\u003cstrong\u003eFigure 4a\u003c/strong\u003e). Pt/TiO\u003csub\u003e2\u003c/sub\u003e could efficiently catalyze the hydrogenation of the above substrates to the corresponding aromatic ring hydrogenated products. The activity followed the order of BA \u0026gt; toluene \u0026gt; benzotrifluoride under similar reaction conditions. The unusual high activity of BA hydrogenation was in contrast to the previous findings that the deficient phenyl ring was difficult to be hydrogenated. This suggests that the carboxyl group may be involved in the whole reaction process although it cannot easily be hydrogenated at mild reaction conditions [10].\u003c/p\u003e\n\u003cp\u003eDFT calculation results showed that the most favorable adsorption configuration of toluene on Pt(111) was the benzene ring adsorption parallel to the metal plane, and the methyl group was far away from the Pt surface. This mainly due to better superposition of its \u0026pi;-orbitals with the Pt conduction band (\u003cstrong\u003eFigure 4b\u003c/strong\u003e) [51,52]. Different from toluene, BA molecule adopted a configuration that an O atom of the carboxyl group was co-adsorbed on the Pt surface. The strong adsorption of BA on Pt/TiO\u003csub\u003e2\u003c/sub\u003e as discussed above may be derived from the co-adsorption of carboxyl group on Pt surface [53]. The dissociated hydrogen stems from the carboxyl group may act as one of the H sources. To confirm this, a control experiment was conducted by using benzoic acid-d\u003csup\u003e5\u003c/sup\u003e and D\u003csub\u003e2 \u003c/sub\u003eas reactants. The MS analysis of the product showed the appearance of molecular ion peaks at m/z of 139.2 and 138.2 with the intensity ratio of 1.9, denoting the presence of 6 deuterated and 5 deuterated CCA in the product (\u003cstrong\u003eFigure 4c\u003c/strong\u003e). An obvious sharp peak at 1.255 was observed in the \u003csup\u003e1\u003c/sup\u003eH-NMR spectrum of the product assigned to the H on the m- or p-position of cyclohexane ring (\u003cstrong\u003eFigure 4c\u003c/strong\u003e), further confirming the results of MS analysis. The above results show that the dissociated H from carboxyl group is involved in the hydrogenation process. To this end, the active Pt\u0026ndash;H species from homolytic dissociation of hydrogen and dissociated H from carboxyl group attack the activated BA molecule to produce CCA. Besides, the adsorption of carboxyl group on Pt/TiO\u003csub\u003e2\u003c/sub\u003e favored the orientation of the aromatic ring on the Pt surface, which may facilitate the hydrogen transfer from Pt surface to BA molecules [54]. On the basis of this mechanism, the Pt with electron deficient surface favored the adsorption and dissociation of carboxyl group, which could enhance the BA hydrogenation activity.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eSubstrate scopes of Pt/TiO\u003csub\u003e2\u003c/sub\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e was also used for the hydrogenation of BA derivatives at mild conditions (\u003cstrong\u003eTable 3\u003c/strong\u003e). Firstly, the hydrogenations of methyl-substituted BA (o-, m-, and p-), p-ethyl benzoic acid and p-pentyl benzoic acid were investigated and the full conversion was obtained in 6 h with the kinetically favored cis isomer [55]. The cis/trans ratio varied in the range of 20/30 to 86/14 (\u003cstrong\u003eTable 3, entry 1-5\u003c/strong\u003e). For p-isopropyl benzoic acid, it needed 10 h to reach full conversion with the cis/trans ratio of 68/32 (\u003cstrong\u003eTable 3, entry 6\u003c/strong\u003e). Even for p-trifluoromethylbenzoic acid with more electron deficient aromatic ring, full conversion was achieved in 10 h though S/C ratio was decreased to 50/1 (\u003cstrong\u003eTable 3, entry 7\u003c/strong\u003e), demonstrating the high activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e. p-Hydroxylbenzoic acid, phenyl propionic acid and phenyl pentanoic acid could be efficiently transferred to corresponding products over Pt/TiO\u003csub\u003e2\u003c/sub\u003e (\u003cstrong\u003eTable 3, entry 8-10\u003c/strong\u003e). The hydrogenation of methyl benzoate, mono-methyl terephthalate and dioctyl phthalate resulted in the formation of the aromatic hydrogenated products using Pt/TiO\u003csub\u003e2\u003c/sub\u003e as catalyst (\u003cstrong\u003eTable 3, entry 11-13\u003c/strong\u003e). It should be mentioned that Pt/TiO\u003csub\u003e2\u003c/sub\u003e could also catalyze the hydrogenation of terephthalic acid, phthalic acid, iso-phthalic acid and even the challenging trimesic acid and trimethyl trimesate to corresponding aromatic ring saturated product under mild conditions, further demonstrating the high efficiency of Pt/TiO\u003csub\u003e2\u003c/sub\u003e for the hydrogenation of aromatic acids (\u003cstrong\u003eTable 3, entry 14-18\u003c/strong\u003e). The hydrogenation of dioctyl phthalate/phthalate acid and trimesic acid/trimethyl trimesate respectively produced the trans and cis isomers, and the hydrogenation of the other substrates investigated in this paper resulted in the formation of cis isomer as the main product on the basis of NMR analysis (see \u003cstrong\u003eSI\u003c/strong\u003e), which may be caused by the steric hindrance effect [56].\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 3\u003c/strong\u003e. Hydrogenation of BA derivatives using Pt/TiO\u003csub\u003e2\u003c/sub\u003e as catalyst.\u003csup\u003ea\u003c/sup\u003e\u003c/p\u003e\u003cp\u003e\u003cimg 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\"\u003e\u003c/p\u003e\n\u003cp\u003e\u003csup\u003ea\u003c/sup\u003eReaction conditions: 40 \u003csup\u003eo\u003c/sup\u003eC, 10 bar H\u003csub\u003e2\u003c/sub\u003e, S/C = 250, 3 mL hexane, \u003csup\u003eb\u003c/sup\u003eSelectivity to ring hydrogenation product; the cis:trans ratio was determined by \u003csup\u003e1\u003c/sup\u003eH-NMR results (See \u003cstrong\u003eSI\u003c/strong\u003e) [57]; \u003csup\u003ec\u003c/sup\u003eChair conformation. \u003csup\u003ed\u003c/sup\u003eS/C= 50; \u003csup\u003ee\u003c/sup\u003e3mL H\u003csub\u003e2\u003c/sub\u003eO; \u003csup\u003ef\u003c/sup\u003e1.5 mL hexane and 1.5 mL acetic acid; \u003csup\u003eg\u003c/sup\u003e60 \u003csup\u003eo\u003c/sup\u003eC; \u003csup\u003eh\u003c/sup\u003e60 \u003csup\u003eo\u003c/sup\u003eC, 1.5 mL H\u003csub\u003e2\u003c/sub\u003eO and 1.5 mL acetic acid; \u003csup\u003ei\u003c/sup\u003e60 \u003csup\u003eo\u003c/sup\u003eC, 20 bar H\u003csub\u003e2\u003c/sub\u003e, 3 mL solvent (10 v/v % H\u003csub\u003e2\u003c/sub\u003eO in n-hexane); \u003csup\u003ej\u003c/sup\u003e80 \u003csup\u003eo\u003c/sup\u003eC, 20 bar H\u003csub\u003e2\u003c/sub\u003e, 3 mL hexane (10 v/v % H\u003csub\u003e2\u003c/sub\u003eO in n-hexane).\u003c/p\u003e\n\u003cp\u003eThe recycle stability of Pt/TiO\u003csub\u003e2\u003c/sub\u003e was investigated using BA hydrogenation as a model reaction (\u003cstrong\u003eFigure 4d\u003c/strong\u003e). The recovered Pt/TiO\u003csub\u003e2\u003c/sub\u003e can be repeatedly used in the hydrogenation reactions, for example in 5 runs of our demonstration, without showing discernible decrease in the conversion of BA or the reaction selectivity. The Pt/TiO\u003csub\u003e2\u003c/sub\u003e after five cycles had similar particle size as the fresh one on the basis of TEM characterizations (\u003cstrong\u003eFigure S6\u003c/strong\u003e), confirming that no aggregation of Pt NPs occurred during recycling process.\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003eIn summary, Pt/TiO\u003csub\u003e2\u003c/sub\u003e was found to be a superior catalyst for BA hydrogenation in comparison with Ru/C and Pd/C due to the weak interaction strength between Pt and BA which inhibited the toxic of BA to the catalyst. A record TOF of 4490 h\u003csup\u003e-1\u003c/sup\u003e was achieved with Pt/TiO\u003csub\u003e2\u003c/sub\u003e under 80 \u003csup\u003eo\u003c/sup\u003eC and 50 bar H\u003csub\u003e2\u003c/sub\u003e in hexane, more than 10 times higher than the literature results under similar conditions. Isotopic studies confirmed that the dissociated hydrogen from the carboxyl group was involved in BA hydrogenation which could be facilitated by the strong adsorption of BA on Pt surface. By comparing the activity of Pt/TiO\u003csub\u003e2\u003c/sub\u003e catalysts with different surface electronic and geometric structures, it could be concluded that electron deficient and low coordination Pt sites had higher catalytic activity than electron rich and high coordination Pt sites in BA hydrogenation, possibly due to the combined effect of higher H\u003csub\u003e2\u003c/sub\u003e activation ability and the stronger adsorption of BA by electron deficient Pt sites. The wide substrate scope including e.g. very challenging terephthalic acid, phthalate acid, phthalic acid, iso-phthalic and trimesic acid demonstrates the potential practical applications of Pt/TiO\u003csub\u003e2\u003c/sub\u003e in hydrogenation of BA and its derivatives.\u003c/p\u003e"},{"header":"Experimental Section","content":"\u003cp\u003e\u003cstrong\u003eChemicals and Materials\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe chemicals were purchased from commercial suppliers and used as received with details listed below: 4-methylbenzoic acid (98%, Innochem (Beijing) chemicals), anisic acid (98%), benzamide (98%), cyclohex-1-ene-1-carboxylic acid (97%) were from ARK Chemicals. dioctyl phthalate (99%), phthalic acid (98%), 4-ethylbenzoic acid (98%), 4-isopropylbenzoic acid (98%) and 4-amylbenzoic acid (98%) were from Aladdin (Shanghai) chemicals. 4-Hydroxybenzoic acid (99%), 2-methylbenzoic acid (98%) and 3-methylbenzoic acid (98%) were from TCI (Shanghai) chemicals. Benzoic-2, 3, 4, 5, 6-d\u003csup\u003e5\u003c/sup\u003e acid (\u0026ge;99 atom % D) was purchased from Macklin Chemicals. Chloroplantinic acid (H\u003csub\u003e2\u003c/sub\u003ePtCl\u003csub\u003e6\u003c/sub\u003e), toluene and other reagents were purchased from Sinopharm Chemical Reagent Co., Ltd. TiO\u003csub\u003e2\u003c/sub\u003e (Rutile, 25-30 nm) was bought from Aladdin (Shanghai) chemicals. Fumed silica (SiO\u003csub\u003e2\u003c/sub\u003e) and Pt/C (5%) were respectively from Sigma-Aldrich and TCI chemicals.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCatalyst Preparation \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation of the Pt/TiO\u003csub\u003e2 \u003c/sub\u003eCatalyst\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePt catalysts with Pt loading of 2 wt% were prepared by the deposition precipitation method using NaBH\u003csub\u003e4\u003c/sub\u003e as the reactant [34, 58]. Typically, 200 mg of TiO\u003csub\u003e2\u003c/sub\u003e and the desired amount of H\u003csub\u003e2\u003c/sub\u003ePtCl\u003csub\u003e6\u003c/sub\u003e (4 mg Pt) was initially dispersed into 50 mL of aqueous solution. After stirring for 1 h at room temperature, a freshly prepared NaBH\u003csub\u003e4\u003c/sub\u003e aqueous solution (2.3 mg, 0.2 mg mL\u003csup\u003e-1\u003c/sup\u003e) was added slowly. After stirring for another 1 h, the solid was collected by filtration and washed with water and ethanol for three times. Finally, the obtained powder was dried at room temperature overnight. The catalyst was denoted as Pt/TiO\u003csub\u003e2\u003c/sub\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation of the Pt/TiO\u003csub\u003e2\u003c/sub\u003e-200 and Pt/TiO\u003csub\u003e2\u003c/sub\u003e-450 Catalyst\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePt/TiO\u003csub\u003e2\u003c/sub\u003e was treated in a H\u003csub\u003e2\u003c/sub\u003e atmosphere with a flow rate of 20 mL min\u003csup\u003e-1\u003c/sup\u003e at the desired temperature for 2 h with a heating rate of 1 \u003csup\u003eo\u003c/sup\u003eC min\u003csup\u003e-1\u003c/sup\u003e. The sample after treatment was denoted as Pt/TiO\u003csub\u003e2\u003c/sub\u003e-T, where T (200 and 450) refers to the treatment temperature.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eSynthesis of Other Oxide Support Loaded Pt Catalyst\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePt/SiO\u003csub\u003e2\u003c/sub\u003e with Pt loading of 2 wt% was prepared by the wet impregnation method by dispersing SiO\u003csub\u003e2\u003c/sub\u003e (200 mg) in 2 mL of aqueous solution of H\u003csub\u003e2\u003c/sub\u003ePtCl\u003csub\u003e6\u003c/sub\u003e (4 mg Pt) for 5 h. Then the solid product after drying by an evaporator and reduced under H\u003csub\u003e2\u003c/sub\u003e atmosphere at 300 \u0026deg;C for 2 h to afford Pt/SiO\u003csub\u003e2\u003c/sub\u003e. Other oxide supported Pt catalysts were prepared with a similar method to Pt/TiO\u003csub\u003e2\u003c/sub\u003e except that the corresponding oxide was used as supports. Analysis by inductively couple plasma atomic emission analysis (ICP-AES) clearly indicated that the desired amounts of metal species were successfully loaded onto each of the catalysts.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCharacterization\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTransmission electron microscopy (TEM) image were obtained using a HITACHI HT7700 at an acceleration voltage of 100 kV. High-resolution scanning electron microscopy (HRSEM) was undertaken by using a HITACHI S5500 apparatus operating at an acceleration voltage of 1-30 kV. X-ray photoelectron (XPS) was performed on an ESCALAB 250xi spectrometer using Al K\u0026alpha; radiation. All the XPS spectra were calibrated by the C1s peak (284.6 eV) from contamination to compensate the charge effects. N\u003csub\u003e2\u003c/sub\u003e sorption isotherms were carried out on a Micromeritics ASAP2020 volumetric adsorption analyzer. Liquid \u003csup\u003e1\u003c/sup\u003eH and \u003csup\u003e13\u003c/sup\u003eC, NMR spectra were recorded on a Bruker Avance 400 MHz spectrometer at 25 \u0026deg;C.\u003c/p\u003e\n\u003cp\u003eIn situ diffuse reflectance infrared Fourier transform spectra (DRIFTS) of CO chemisorption was measured on a Thermo Scientific IR spectrometer with a mercury cadmium telluride (MCT) detector, recorded with a resolution of 4 cm\u003csup\u003e\u0026minus;1\u003c/sup\u003e [59]. Prior to CO adsorption, the samples were treated in situ in the DRIFT cell under a H\u003csub\u003e2\u003c/sub\u003e flow (20 mL min\u003csup\u003e\u0026minus;1\u003c/sup\u003e) at the desired temperatures for 1 h, followed by purging with a He flow at the same temperature for 30 min. After cooling to room temperature, a background spectrum was collected. Then the He flow was switched to a pure CO flow (20 mL min\u003csup\u003e\u0026minus;1\u003c/sup\u003e) until saturated adsorption was achieved. CO adsorption experiments were carried out sequentially on a single sample. Gas-phase CO spectra were collected at the same pressure and subtracted from the corresponding sample spectra.\u003c/p\u003e\n\u003cp\u003eCO/H\u003csub\u003e2\u003c/sub\u003e chemisorption measurement was performed at 50 \u0026deg;C on a Autochem II 2920 chemisorption instrument with a thermal conductivity detector (TCD). The sample (~100 mg) was pretreated with hydrogen at desired temperatures for 1 h, followed by purging with high-purity He (or Ar) for 30 min. After the sample was cooled down to 50 \u0026deg;C, a 5% CO/He (or 10% H\u003csub\u003e2\u003c/sub\u003e/Ar) mixture was injected into the reactor repeatedly until CO (or H\u003csub\u003e2\u003c/sub\u003e) adsorption was saturated. The dispersion of Pt was calculated from the amount of CO adsorbed by assuming the CO/Pt adsorption stoichiometry to be 1/1.\u003c/p\u003e\n\u003cp\u003eH\u003csub\u003e2\u003c/sub\u003e\u0026minus;D\u003csub\u003e2\u003c/sub\u003e exchange reactions were carried out in a flow quartz reactor at 22 \u0026deg;C [60]. The formation rate of HD was measured by mass signal intensity (ion current). Before the test, the catalysts were heated in H\u003csub\u003e2\u003c/sub\u003e (10 mL min\u003csup\u003e\u0026minus;1\u003c/sup\u003e) at 200 \u0026deg;C for 20 min. After the sample was cooled down to room temperature, D\u003csub\u003e2\u003c/sub\u003e (10 mL min\u003csup\u003e\u0026minus;1\u003c/sup\u003e) mixed with H\u003csub\u003e2\u003c/sub\u003e was passed through the sample. The gas hourly space velocity (GHSV) is 2.9 \u0026times; 10\u003csup\u003e7\u003c/sup\u003e mL h\u003csup\u003e\u0026minus;1\u003c/sup\u003e g\u003csub\u003emetal\u003c/sub\u003e \u003csup\u003e\u0026minus;1\u003c/sup\u003e. Under these conditions, the H\u003csub\u003e2\u003c/sub\u003e\u0026minus;D\u003csub\u003e2\u003c/sub\u003e exchange conversions were always kept below 15% for calculation of turnover frequency (TOF) [61]. Products (HD, H\u003csub\u003e2\u003c/sub\u003e, and D\u003csub\u003e2\u003c/sub\u003e) were analysed with an online mass spectrometer (GAM200, InProcess Instruments). The mass/charge ratio (m/z) values used are 2 for H\u003csub\u003e2\u003c/sub\u003e, 4 for D\u003csub\u003e2\u003c/sub\u003e, and 3 for HD. The background HD exchanges from the corresponding support were deducted from the results.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eGeneral Procedure for the Hydrogenation of Benzoic Acid (BA).\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe hydrogenation reactions were carried out in a stainless steel autoclave (300 mL) with a thermocouple-probed detector. In a typical process for benzoic acid (BA) hydrogenation, a desired amount of the solid catalyst was placed in an ampule tube, followed by the addition of BA (0.12 mmol) and 3 mL of n-hexane (for reaction performed at S/C of 1200, 0.3 mL of acetic acid was added to assist the dissolution of BA). The ampule tube was loaded into the reactor. After the tube was purged six times with hydrogen, the final pressure was adjusted to 10 bar and the reactor was heated to desired temperature with vigorous stirring. After the reaction, the solid catalyst was separated by centrifugation and the filtrate was collected, diluted with n-hexane, and analyzed by an Agilent 6890N GC instrument equipped with an Agilent J\u0026amp;W GC HP-INNOWax capillary column (30 m \u0026times; 0.32 mm \u0026times; 0.25 \u0026mu;m). The diphenyl ether was used as the internal standard to determine the conversion, selectivity and carbon balance. The carbon balance was ~ 100%.\u003c/p\u003e\n\u003cp\u003eFor the recycle experiments, the liquid was decanted after centrifugation of the reaction mixture. The residual catalyst was thoroughly washed with n-hexane, and used directly for the next run.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eComputational Setup\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll the calculations were performed with density functional theory (DFT) by using the Vienna Ab-initio Simulation Package (VASP) [62,63]. The projector augmented-wave pseudopotential method with Perdew-Burke-Ernzerhof (PBE) exchange-correlation functional including zero-damping DFT-D3 of Grimme\u0026rsquo;s correction was employed [64,65]. A plane-wave basis with cutoff energy of 400 eV was adopted. Four-atomic-layer slab models of Pt(111), Pd(111), and Ru(0001) with the bottom two layers fixed consisting of 144 metal atoms were built. The vacuum spaces were set as 15 \u0026Aring; between the layers. A gamma k-point sampling of 1\u0026times;1\u0026times;1 was selected. The convergence energy and force were set to be 1 \u0026times; 10\u003csup\u003e\u0026minus;5\u003c/sup\u003e eV and 0.02 eV/\u0026Aring;, respectively.\u003c/p\u003e\n\u003cp\u003eThe adsorption energy E\u003csub\u003ead\u003c/sub\u003e was calculated as:\u003c/p\u003e\n\u003cp\u003eE\u003csub\u003ead\u003c/sub\u003e = E\u003csub\u003ead/sub\u003c/sub\u003e \u0026minus; E\u003csub\u003emol\u003c/sub\u003e \u0026minus; E\u003csub\u003esub\u003c/sub\u003e\u003c/p\u003e\n\u003cp\u003eThe E\u003csub\u003eads/sub\u003c/sub\u003e, E\u003csub\u003emol\u003c/sub\u003e and E\u003csub\u003esub\u003c/sub\u003e are the total energy of the adsorbed molecule, the molecule in the gas phase, and the pure slab, respectively.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eACKNOWLEDGMENTS\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe acknowledge financial support from the National Key R\u0026amp;D Program of China (2017YFB0702800), the National Natural Science Foundation of China (21733009), and the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB17020200).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAUTHOR CONTRIBUTIONS\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eQ. H. Y. conceived the idea. Q. H. Y., M. G., X. T. K. and C. Z. L. co-wrote the paper. M. G. synthesized the nanomaterials and carried out the catalysis experiments. X. T. K. carried out the model construction and DFT calculations. C. Z. L. analyzed part of NMR results. All the authors contributed to the overall scientific interpretation and edited the manuscript.\u003c/p\u003e"},{"header":"References","content":"\u003cp\u003e[1] B. S. Moore, H. Cho, R. Casati, E. Kennedy, K. A. Reynolds, U. Mocek, J. M. Beale, H. G. Floss, Biosynthetic studies on ansatrienin A. formation of the cyclohexanecarboxylic acid moiety, J. Am. Chem. Soc.\u003cem\u003e,\u003c/em\u003e 115 (1993) 5254\u0026minus;5266.\u003c/p\u003e\n\u003cp\u003e[2] X. Ren, M. Guo, H. Li, C. Li, L. Yu, J. Liu, Q. Yang, Microenvironment engineering of Ruthenium nanoparticles incorporated into Silica nanoreactors for enhanced hydrogenations. Angew. Chem. Int. Ed., 7 (2019) 14483-14488.\u003c/p\u003e\n\u003cp\u003e[3] R. Raja, T. 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Phys., 132 (2010) 154104\u0026ndash;19.\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"nature-portfolio","isNatureJournal":true,"hasQc":false,"allowDirectSubmit":false,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"","title":"Nature Portfolio","twitterHandle":"","acdcEnabled":false,"dfaEnabled":false,"editorialSystem":"ejp","reportingPortfolio":"","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"Pt/TiO2, Hydrogenation, Anti-Poison, Benzoic Acid, Terephthalic Acid, Trimesic Acid","lastPublishedDoi":"10.21203/rs.3.rs-108586/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-108586/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThe hydrogenation of benzoic acid (BA) to corresponding cyclohexanecarboxylic acid has important industry and academia significance, however, the electron deficient aromatic ring and the catalyst \u0026ldquo;poison\u0026rdquo; by carboxyl group make BA hydrogenation as one of the most challenging transformations. Herein, we found that Pt NPs deposited on TiO\u003csub\u003e2\u003c/sub\u003e were very effective for BA hydrogenation with a record TOF of 4490\u0026nbsp;h\u003csup\u003e\u0026minus;\u0026thinsp;1\u003c/sup\u003e under 80 \u003csup\u003eo\u003c/sup\u003eC and 50\u0026nbsp;bar H\u003csub\u003e2\u003c/sub\u003e in hexane, one order higher than the reported results. DFT calculation showed that Pt NPs had a weaker interaction with BA than Ru and Pd NPs commonly used for BA hydrogenation, which improved the toxicity resistance of catalyst to BA. Pt/TiO\u003csub\u003e2\u003c/sub\u003e catalysts with electron deficient and electron enriched Pt sites were successfully synthesized by modifying the electron transfer direction between Pt and TiO\u003csub\u003e2\u003c/sub\u003e. Isotopic experiments suggested the participation of dissociated H from carboxyl group in BA hydrogenation. Consequently, the electron deficient Pt sites with stronger adsorption of BA were more active than electron rich Pt sites in BA hydrogenation. In addition to BA, terephthalic acid, iso-phthalic acid, trimesic acid and other BA derivatives could also be efficiently converted to corresponding aromatic saturated products, demonstrating the wide substrate scope of Pt/TiO\u003csub\u003e2\u003c/sub\u003e.\u003c/p\u003e","manuscriptTitle":"Pt/TiO2 Catalyzed Hydrogenation of Benzoic Acid with Unprecedented High Activity","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-12-04 15:15:27","doi":"10.21203/rs.3.rs-108586/v1","editorialEvents":[],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"communications-chemistry","isNatureJournal":true,"hasQc":false,"allowDirectSubmit":false,"externalIdentity":"commschem","sideBox":"Learn more about [Communications Chemistry](http://www.nature.com/commschem/)","snPcode":"","submissionUrl":"","title":"Communications Chemistry","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"ejp","reportingPortfolio":"Communications Series","inReviewEnabled":true,"inReviewRevisionsEnabled":false}}],"origin":"","ownerIdentity":"339405e1-e473-49e9-ac7b-aed377294d2c","owner":[],"postedDate":"December 4th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":1324897,"name":"Catalysis"}],"tags":[],"updatedAt":"2021-11-22T15:44:49+00:00","versionOfRecord":{"articleIdentity":"rs-108586","link":"https://doi.org/10.1038/s42004-021-00489-z","journal":{"identity":"communications-chemistry","isVorOnly":false,"title":"Communications Chemistry"},"publishedOn":"2021-04-16 04:00:00","publishedOnDateReadable":"April 16th, 2021"},"versionCreatedAt":"2020-12-04 15:15:27","video":"","vorDoi":"10.1038/s42004-021-00489-z","vorDoiUrl":"https://doi.org/10.1038/s42004-021-00489-z","workflowStages":[]},"version":"v1","identity":"rs-108586","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-108586","identity":"rs-108586","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}