A unique case of Takotsubo cardiomyopathy following a simple partial seizure

A 67-year-old woman presented to the emergency department for a simple partial seizure of her left upper and lower limbs that lasted for 1 hour and ultimately resolved before her presentation. She has no history of coronary artery disease, and her neurological exam was normal. Five hours later, she complained of chest pain, and an electrocardiogram showed ST-segment elevation in the lateral leads, and her troponin level was increased. We diagnosed her with Takotsubo cardiomyopathy. This case reflects the brain-heart connection and is the first reported case of Takotsubo cardiomyopathy following a simple partial seizure.