The modern concept of the pathogenesis of chronic pelvic pain syndrome induced denomyosis

Chronic pelvic pain (CPP) is a significant public health problem affected women in the world. Although many pathologies are associated with CPP, the pain experienced is often disproportionate to the extent of disease identified and frequently no pathology is found (chronic pelvic pain syndrome). Adenomyosis - a pathological condition characterized by the presence of ectopic endometrial glands and stroma in the myometrium thickness combined with hyperplasia of muscle fibers [6]. The syndrome of chronic pelvic pain of endometriosis is one of the most urgent problems of modern gynecology [8]. The evidence reviewed in this paper demonstrates that CPP is associated with significant central changes women. Moreover, the presence of these changes has the potential to both exacerbate symptoms and to predispose these women to the development of additional chronic conditions.