SPECT/CT imaging of a retroperitoneal nodule in a patient with history of infiltrating renal urothelial carcinoma.

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This case report describes using SPECT/CT imaging with Tc-99m labeled denatured red blood cells to definitively diagnose a retroperitoneal nodule as a relocated splenule rather than recurrent urothelial carcinoma.

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AI-generated deep summary by qwen3.7-flash, 2026-08-24 · read from full text

This case report describes the diagnostic evaluation of a 62-year-old woman with a history of high-grade infiltrating renal urothelial carcinoma who presented with a 1 cm retroperitoneal nodule in her nephrectomy bed. The clinical team utilized SPECT/CT imaging with Tc-99m labeled denatured red blood cells to differentiate between recurrent malignancy and an accessory spleen, ultimately confirming the lesion as a relocated splenule. The study highlights the utility of this specific nuclear medicine technique in resolving ambiguous findings post-surgery without requiring invasive biopsy. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

A 62 year old woman status post radical nephroureterectomy for high grade urothelial carcinoma was found on CT to have a 1 cm retroperitoneal nodule in the nephrectomy bed. The nodule's differential diagnosis included recurrent urothelial carcinoma versus relocation of the patient's splenule seen on earlier CT imaging. We report using SPECT/CT with Tc-99m labeled denatured red blood cells to definitively diagnose the nodule as a relocated splenule.
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SPECT/CT imaging of a retroperitoneal nodule in a patient with history of infiltrating renal urothelial carcinoma DOI: https://doi.org/10.3941/jrcr.v3i9.285Keywords: SPECT/CT, Splenule, Accessory Spleen, Renal Urothelial Carcinoma, NephrectomyAbstract A 62 year old woman status post radical nephroureterectomy for high grade urothelial carcinoma was found on CT to have a 1 cm retroperitoneal nodule in the nephrectomy bed. The nodule's differential diagnosis included recurrent urothelial carcinoma versus relocation of the patient's splenule seen on earlier CT imaging. We report using SPECT/CT with Tc-99m labeled denatured red blood cells to definitively diagnose the nodule as a relocated splenule. Downloads Published Issue Section License The publisher holds the copyright to the published articles and contents. However, the articles in this journal are open-access articles distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License, which permits reproduction and distribution, provided the original work is properly cited. The publisher and author have the right to use the text, images and other multimedia contents from the submitted work for further usage in affiliated programs. Commercial use and derivative works are not permitted, unless explicitly allowed by the publisher.

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