Heterogeneity of Obesity and Its Predictive Factors

With the increasing prominence of "obesogenic environments", obesity has emerged as a major challenge to human health. Notably, humans and animals have different responses to the obesogenic environment created by affluent societies, and the susceptibility of both humans and animals to diet-induced obesity appears to be a stable phenotype. Biomarkers and specific genes, which influence body composition through long-term exposure to obesogenic environments, have been identified as higher risk indicators of individuals future weight gain. By utilizing a broad range of pre-exposure characteristics as predictive factors, we can better quantify the heterogeneity of obesity, offering novel perspectives for personalized clinical prevention and treatment.