Clinical Insights into Idiopathic Stroke in Young Adults: A Multi-Case Review

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This case series details three young adults experiencing strokes, presenting diverse neurological deficits and stroke types, highlighting the rising incidence and need for awareness in this demographic.

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This multi-case review investigates idiopathic stroke in young adults under age 45, presenting three cases without pre-existing medical conditions identified via CT imaging after acute neurologic presentations during travel on cruise ships. The cases included a 43-year-old woman with acute left cerebellar ischemic stroke, a 42-year-old man with right basal ganglia intracerebral hemorrhage, and a 22-year-old man with right occipital intracerebral hemorrhage, with the authors emphasizing rising incidence in young adults and regional disparities among Asians. A key limitation is that it is based on only three cases and is a preprint that has not been peer reviewed, limiting generalizability and diagnostic completeness. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Abstract Incidence of stroke has risen in young adults under 45 years of age globally. In this case series, we present three cases of stroke in young adults without pre-existing medical conditions. Our first case is a 43-year-old female cruise line employee from Thailand who experienced dizziness and loss of consciousness following a fall 8 days prior, revealing an acute left cerebellar stroke on CT scan. The second case involves a 42-year-old male from the Philippines, with no significant medical history, transferred from Bermuda after being found unresponsive on a cruise ship, with CT brain imaging showing right basal ganglia intracerebral hemorrhage. The third case is a 22-year-old male from Pakistan presenting with a two-day history of severe occipital headache, vomiting, and confusion, revealing intracerebral hemorrhage in the right occipital lobe on CT scan. Discussion focuses on the rising incidence of strokes in young adults, regional disparities, risk factors, and the need for tailored interventions. This review emphasizes the importance of ongoing research and increased awareness and high index of suspicion to improve outcomes in this vulnerable population, particularly among Asians, aiming to mitigate the devastating impact of strokes in this age group.
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In this case series, we present three cases of stroke in young adults without pre-existing medical conditions. Our first case is a 43-year-old female cruise line employee from Thailand who experienced dizziness and loss of consciousness following a fall 8 days prior, revealing an acute left cerebellar stroke on CT scan. The second case involves a 42-year-old male from the Philippines, with no significant medical history, transferred from Bermuda after being found unresponsive on a cruise ship, with CT brain imaging showing right basal ganglia intracerebral hemorrhage. The third case is a 22-year-old male from Pakistan presenting with a two-day history of severe occipital headache, vomiting, and confusion, revealing intracerebral hemorrhage in the right occipital lobe on CT scan. Discussion focuses on the rising incidence of strokes in young adults, regional disparities, risk factors, and the need for tailored interventions. This review emphasizes the importance of ongoing research and increased awareness and high index of suspicion to improve outcomes in this vulnerable population, particularly among Asians, aiming to mitigate the devastating impact of strokes in this age group. Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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