Large leiomyomas in Mayer-Rokitansky-Küster-Hauser syndrome

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AI-generated summary by claude@2026-06, 2026-06-10

This paper describes a rare case of a patient with Mayer-Rokitansky-Küster-Hauser syndrome who presented with leiomyomas arising from both rudimentary uterine horns.

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Abstract

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome (mullerian agenesis) is a cause of primary amenorrhoea; second in frequency only to gonadal dysgenesis. Women with this syndrome are characterized by presence of 46 XX karyotype, female secondary sex characters, normal ovarian functions including cyclic ovulation and undeveloped vagina. The uterus usually consists of rudimentary bicornuate cords 1,2. Occurrence of leiomyoma in a patient with mullerian agenesis has not been described in the literature. We present a patient with mullerian agenesis who was found to have leiomyomas arising from both of the rudimentary horns of the uterus.

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last seen: 2026-06-10T17:14:06.276822+00:00
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