Traces of pubertal brain development and health revealed through domain adapted brain network fusion

Puberty demarks a period of profound brain dynamics that orchestrates changes to a multitude of neuroimaging-derived phenotypes. This poses a dimensionality problem when attempting to chart an individual’s brain development on a single scale. Here, we illustrate shifts in subject similarity of imaging data that relate to pubertal maturation and altered mental health, suggesting that dimensional reference spaces of subject similarity render useful to chart brain dynamics in youths.