COVID-19 – Present Treatments and Other Options

Objective: This article aims to examine the effectiveness of antiviral drugs and vaccines that are frontrunners in the treatment of COVID-19 and explore the possibility of other options. Methods: Sixty-plus review articles and clinical studies published in MEDLINE-PubMed, Cochran Library, Clinical Trials Gov, NIH, WHO, Google Scholars and Medical Journals were searched. Out of sixty studies and clinical trials, twenty-nine were selected. The inclusion criteria were large randomized scale clinical trials and unbiased articles. Studies with bias using the Cochran risk of bias tool for randomized studies were excluded. Results: It has almost a year when the first case of SARS-CoV-2 infection was reported. Since then, the search for an effective antiviral drug is continuing. Remdesivir, convalescent plasma, and dexamethasone are the only available options with limited effectiveness. Conclusion: The need for developing an antiviral drug against COVID-19 is more than ever. Searching the compounds with antiviral activity against COVID-19 from various sources, including plants, fungus, and bacteria may have the answer.Funding Statement: None.Declaration of Interests: None.Ethics Approval Statement: No ethics committee or institutional review board was necessary because studies were already available in the literature.