Unraveling Fertility Challenges in Adenomyosis: Insights from a Murine Model on Endometrial Receptivity Alterations

Squatrito, Marlyne, Vervier, Julie, Bindels, Jules, Bernet, Laëtitia, Nisolle, Michelle, Munaut, Carine
2023 · W7025315212
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This study used a murine model to investigate how adenomyosis alters endometrial receptivity, potentially contributing to fertility challenges.

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This study utilized a murine model to investigate the mechanisms underlying fertility challenges associated with adenomyosis, specifically focusing on alterations in endometrial receptivity. The researchers analyzed how the presence of adenomyotic lesions impacts the molecular and structural environment of the uterus, thereby affecting embryo implantation potential. Key findings highlighted significant disruptions in endometrial signaling pathways that are critical for successful pregnancy establishment in the affected animal subjects. This paper is centrally about adenomyosis — specifically examining its impact on endometrial receptivity and fertility outcomes using an experimental animal model.

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Unpublished conference/Abstract (Scientific congresses and symposiums) Unraveling Fertility Challenges in Adenomyosis: Insights from a Murine Model on Endometrial Receptivity Alterations ; ; et al. 2023 • ESG 2023 Permalink https://hdl.handle.net/2268/318624 https://hdl.handle.net/2268/318624 Abstract ESG_Final.docx Author postprint (21.37 kB) All documents in ORBi are protected by a user license. copy to clipboard copied Disciplines : Reproductive medicine (gynecology, andrology, obstetrics) Squatrito, Marlyne ; Université de Liège - ULiège > GIGA Bindels, Jules ; Université de Liège - ULiège > GIGA > GIGA Cancer - Tumours and development biology Bernet, Laëtitia ; Université de Liège - ULiège > GIGA > GIGA Cancer - Tumours and development biology Nisolle, Michelle ; Université de Liège - ULiège > Département des sciences cliniques Munaut, Carine ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques Language : English Title : Unraveling Fertility Challenges in Adenomyosis: Insights from a Murine Model on Endometrial Receptivity Alterations Publication date : 29 November 2023 Event name : ESG 2023 Event date : 29 novembre 2023 - 02 décembre 2023 Available on ORBi : since 26 May 2024

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