Assessing DWI Positivity in Clinically Diagnosed TIA: Insights from a Cohort Study in Cluj, Romania

The updated definition of TIA emphasizes tissue characteristics rather than symptom duration, defining TIA as a transient neurological episode without ischemic lesions on brain imaging, including DWI. If imaging reveals a lesion, even in patients with transient symptoms, the event is reclassified as a minor ischemic stroke. This retrospective cross-sectional study aimed to determine the period prevalence of ischemic lesions on DWI in patients with TIA diagnosis. Adults aged 18–90 years, diagnosed with TIA by a neurologist, and who underwent MRI-DWI at CMT hospital within the first week after symptom onset (May 2023–July 2024) were included. Ethical approval was obtained. Descriptive statistics summarized patient demographics, clinical features, Fazekas scale grades, and imaging findings. Among the 26 patients clinically diagnosed with TIA, 7 (26.9%) exhibited ischemic lesions on DWI, reclassifying these cases as minor ischemic strokes under the updated definition. The prevalence of ischemic lesions was notably higher in patients with comorbidities such as hypertension and diabetes. The findings highlight the importance of early MRI-DWI in accurately distinguishing TIAs from minor ischemic strokes. Routine urgent DWI within the first week of TIA symptoms enhances diagnosis, risk stratification, and guides targeted stroke prevention strategies, particularly when combined with the ABCD2 score.