Predictive Value of Endometriosis Fertility Index in Treatment of Intrauterine Insemination for Endometriosis Complicated with Infertility

Objective: To study the predictive value of the endometriosis fertility index(EFI) for the clinical pregnancy rate in intrauterine insemination(IUI) treatment cycles for endometriosis patients complicated with infertility.Methods:The clinical data of 75 endometriosis patients complicated with infertility after laparoscopic surgery undergoing125 IUI cycles were analyzed. EFI score was calculated according to the endometriosis fertility index system, the ROC curve was used to assess the predictive value of EFI for the clinical pregnancy rate of IUI. Results:The areas under ROC curve of EFI and r-AFS were 0.708±0.059(P0.05)and 0.375±0.065(P0.05)respectively. The best point for diagnosis by EFI was 7, the sensitivity was 0.737 and the specificity was 0.613. The clinical pregnancy rate of EFI≤6, 7, 8, 9, 10 was 3.1%,10.5%, 21.1%, 27.8%, 27.8% respectively. Compare to the group of EFI≤6, the clinical pregnancy rate of EFI=8, 9 and 10 was significantly higher(P0.05). Conclusions:EFI can be used as a good and effective tool to predict pregnancy outcome in the endometriosis-associated infertile patients attempted to IUI after laparoscopic surgery, the clinical pregnancy rate was obviously increased among EFI≥8, which can provide an important basis for assisted reproductive technology treatment.