Ovarian Overstimulation, Massive Ascites, and Singleton Pregnancy After Clomiphene

Antonio Scommegna
In: JAMA: The Journal of the American Medical Association · 1969 · vol. 207(4) , pp. 753 · doi:10.1001/jama.1969.03150170079022 · PMID:5818198 · W2063632787
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

A patient developed bilateral ovarian enlargement with massive ascites and pregnancy after clomiphene therapy, suggesting the second course was administered during early pregnancy.

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Abstract

Bilateral ovarian enlargement with massive ascites and pregnancy occurred in a patient after two courses of clomiphene citrate (Clomid) therapy. It is likely that the patient received the second course of clomiphene during early stages of pregnancy. Early pregnancy must be ruled out prior to the administration of this type of therapy.

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