Assessing Uterine Myomas and adenomyosis with BOLD Imaging After MRI-Guided Focused Ultrasound: Preliminary Findings

Po‐Han Chuang, Yuhan Yang, Liwen Liu, Shuangying Wei, Su-Yuan Wei, Chia‐Wei Lee, Chien‐Yuan Lin, Yu‐Chun Lin, Shyh‐Jye Chen
In: ISMRM Annual Meeting · 2025 · doi:10.58530/2025/5173 · W4414233807
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This preliminary study validates T2*-mapping with iDEAL-IQ as a contrast-free tool for assessing high-intensity focused ultrasound treatment outcomes in uterine myomas and adenomyosis by monitoring lesion oxygenation changes.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-24 · read from full text ⓘ

This preliminary study investigates the utility of T2*-mapping using iDEAL-IQ for assessing treatment efficacy in utine myomas and adenomyosis following high-intensity focused ultrasound. The researchers observed that T2* values, which reflect tissue oxygenation, decreased in lesion regions under varying oxygenation conditions but remained equal or increased after successful HIFU treatment. These findings indicate that non-contrast T2*-mapping can effectively monitor therapeutic outcomes by revealing post-treatment oxygenation variations. This paper is centrally about adenomyosis — specifically using MRI-based T2*-mapping to evaluate the effectiveness of HIFU treatment for adenomyosis lesions.

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Abstract

Motivation: Evaluating treatment efficacy of high-intensity focused ultrasound (HIFU) is crucial for physicians to determine whether the procedure is complete. Goal(s): This preliminary study validates the use of T2*-mapping with iDEAL-IQ for evaluating the treatment effects of HIFU without contrast injection. Approach: A decrease in T2* values was observed in the lesion region between different oxygenation conditions, while equal or increased values were noted after treatment. Results: These preliminary results suggest that T2* mapping could be an effective tool for treatment assessment. Impact: T2*-mapping, which can reveal the variations in oxygenation, would be an effective tool for assessing treatment outcomes of high-intensity focused ultrasound (HIFU) in uterine myomas and adenomyosis, without the need for contrast injection.
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Abstract

#5173 Po-Han Chuang1,2, Yu-Han Yang1, Li-Wen Liu1, Su-Yuan Wei1, Chia-Wei Lee3, Chien-Yuan Lin3, Yu-Chun Lin2, and Shyh-Jye Chen1 1Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan, 2Institute of Medical Device and Imaging, College of Medicine, National Taiwan University, Taipei, Taiwan, 3GE Healthcare, Taipei, Taiwan

Keywords

Pelvis, Treatment, HIFU Motivation: Evaluating treatment efficacy of high-intensity focused ultrasound (HIFU) is crucial for physicians to determine whether the procedure is complete. Goal(s): This preliminary study validates the use of T2*-mapping with iDEAL-IQ for evaluating the treatment effects of HIFU without contrast injection. Approach: A decrease in T2* values was observed in the lesion region between different oxygenation conditions, while equal or increased values were noted after treatment.

Results

These preliminary results suggest that T2* mapping could be an effective tool for treatment assessment. Impact: T2*-mapping, which can reveal the variations in oxygenation, would be an effective tool for assessing treatment outcomes of high-intensity focused ultrasound (HIFU) in uterine myomas and adenomyosis, without the need for contrast injection. How to access this content: For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library. After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library. After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers. Keywords

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adenomyosis

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