PHARMACEUTICAL PREPARATION FOR THE ALLEVIATION OF ENDOMETRIOSIS

A pharmaceutical composition for the treatment of endometriosis without l oss of bone density comprises a gestagenic having an antiandrogenic effect, preferably 17.alpha.-cyanomethyl-17ss-hydroxy-estra-4,9-diene-3-one (Dienoges t), cyproteronacetate or chlormadinonacetate at a daily dosage which is no m ore than two times the dosage required to suppress ovulation, together with one or a plurality of pharmaceutically acceptable adjuvants/carriers. The ph armaceutical composition according to the invention provides both the allevi ation of endometriosis and the lack of a negative affect on bone metabolism and bone density, and is simultaneously able to keep the side effects known from conventional pharmaceuticals (such as hot flashes, acne, negative affec ts on the lipid profile) within tolerable limits. The pharmaceutical composi tion is thus suitable for long-term application.