Elagolix as a Novel Treatment for Endometriosis-Related Pain

Fantasia HC, Heidi Collins Fantasia
Nursing for women's health · 2019 · vol. 23(4) , pp. 366–369 · doi:10.1016/j.nwh.2019.05.004 · PMID:31276630 · W2953455145
article OA: closed CC0 ⤵ 2 in-corpus citations
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Elagolix was evaluated as a novel treatment for endometriosis-related pain in this study.

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Abstract

Endometriosis, which is the growth of endometrial tissue outside of the uterus, is estimated to affect up to 10% of reproductive-age women. Symptoms associated with endometriosis include dysmenorrhea, chronic pelvic pain, and dyspareunia. In July 2018, the U.S. Food and Drug Administration approved elagolix (Orilissa, AbbVie, North Chicago, IL) as an oral treatment for endometriosis-related pain. This medication is a gonadotropin-releasing hormone receptor antagonist that works by suppressing levels of hormones, including estrogen and progesterone. This helps decrease inflammation and the proliferation of endometrial tissue. In this column, I provide an overview of elagolix and discuss contraindications, adverse effects, and practice implications for nurses who work with women affected by endometriosis.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Abdominal Pain Endometriosis Hydrocarbons, Fluorinated Pyrimidines Abdominal Pain Abdominal Pain Abdominal Pain Adult Drug Therapy Drug Therapy Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Female Hormone Antagonists Hormone Antagonists Hormone Antagonists Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (2)

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