Editorial: Host-pathogen interactions during pregnancy: mechanisms of maternal and fetal immunity

Alippe Y, Yael Alippe, Hauk V, Vanesa Hauk, Gil Mor, Daiana M Vota, Vota DM
Frontiers in immunology · 2025 · vol. 16 , pp. 1629528 · doi:10.3389/fimmu.2025.1629528 · PMID:40557141 · PMC12185400
Other OA: gold CC-BY-4.0
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This editorial discusses the mechanisms of maternal and fetal immunity, focusing on host-pathogen interactions that occur during pregnancy.

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This editorial article reviews the complex mechanisms governing host-pathogen interactions during pregnancy, focusing on the intricate balance between maternal and fetal immunity. The authors discuss how these immunological processes are critical for maintaining a healthy gestation while protecting both mother and developing fetus from infectious threats. The text serves as an overview of current understanding in reproductive immunology without presenting new primary experimental data or clinical trial results. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Author

YA: Writing – original draft, Writing – review & editing. VH: Writing – original draft, Writing – review & editing. GM: Writing – original draft, Writing – review & editing. DV: Writing – original draft, Writing – review & editing.

Conflict

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

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The author(s) declare that no Generative AI was used in the creation of this manuscript.

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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europepmc
last seen: 2026-10-11T09:27:45.537177+00:00
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