CLINICAL EFFECT OF U-SHAPED EXCISION FOR BODY OF UTERUS ON DIFFUSE ADENOMYOSIS

Objective To assess the feasibility and safety of U-shape excision of body of uterus in the therapy of diffuse adenomyosis. Methods Seventy patients with diffuse adenomyosis were evenly randomized to study group(U-shape-excision group) control group(complete hysterectomy).A comparison between the two groups was done in terms of the following items: intraoperative blood loss,operation time;serum levels of estradiol(E2),follicle stimulating hormone(FSH) and luteinizing hormone(LH) at one month before and six months after surgery;quality of sexual life before and six months after surgery,the extent of algomenorrhea,and serum levels of CA125 and the volume of the body of uterus in the study group. Results The differences between the two groups were not significant in terms of operation time and blood loss at surgery(P0.05).In the study group,the differences between serum levels of E2,FSH and LH before and after surgery were not significant(P0.05),while that in the control group,the differences were significant(t=2.45-2.70,P0.05).The extent of algomenorrhea,the level of serum CA125 decreased in both groups six months postoperatively(t=2.23-2.56,P0.05).The quality of sexual life in the control group obviously degraded after surgery(t=2.36,P0.05). Conclusion The U-shaped excision of the body of uterus is to remove the diseased tissue and reserve the uterus with no impact on blood supply of the ovaries.This is the first choice for those with adenomyosis that needs to be treated by surgery,and wish the uterus be reserved.