False-positive diagnosis of uterine malignancy with raised 18F-fluorodeoxyglucose activity in adenomyosis: A case report

Wong, Wu Shun Felix, Kwok To Thomas Li
2022 · doi:10.5281/zenodo.6349819 · W6931730755
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Abstract

Positron Emission Tomography - Computed Tomography (PET-CT) has been used to diagnose malignancy before surgery. However, there may be an increase in 18F-fluorodeoxyglucose (FDG) uptake in PET scans in benign conditions, leading to a false-positive diagnosis of malignancy and unnecessary surgery. This PET-CT investigation is expensive and is not without risk, including radiation and drug or contrast hypersensitivity. Although variable uterine uptakes of FDG activities in PET-CT had been reported in the literature, unawareness of its possibility in benign conditions could lead to a false alarm of malignancy. This paper reported a patient with a false-positive FDG finding presenting as a malignant uterine lesion for surgery, aiming to raise the clinical awareness of this finding.
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False-positive diagnosis of uterine malignancy with raised 18F-fluorodeoxyglucose activity in adenomyosis: A case report Authors/Creators - 1. Department of Obstetrics and Gynaecology, School of Women's and Children's Health, The University of New South Wales, Sydney, Australia. - 2. Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, China. Description Positron Emission Tomography - Computed Tomography (PET-CT) has been used to diagnose malignancy before surgery. However, there may be an increase in 18F-fluorodeoxyglucose (FDG) uptake in PET scans in benign conditions, leading to a false-positive diagnosis of malignancy and unnecessary surgery. This PET-CT investigation is expensive and is not without risk, including radiation and drug or contrast hypersensitivity. Although variable uterine uptakes of FDG activities in PET-CT had been reported in the literature, unawareness of its possibility in benign conditions could lead to a false alarm of malignancy. This paper reported a patient with a false-positive FDG finding presenting as a malignant uterine lesion for surgery, aiming to raise the clinical awareness of this finding. Files WJARR-2022-0178.pdf Files (960.9 kB) | Name | Size | Download all | |---|---|---| | md5:53440d2936a7f9b6ad8c7992edad0a55 | 960.9 kB | Preview Download |

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