Autologous cryopreserved decellularized glutaraldehyde-treated human pericardium for redo aortic valve repair
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This paper reports a successful application of cryopreserved decellularized glutaraldehyde-treated autologous pericardium for redo aortic valve repair in a pediatric patient with cusp prolapse and limited valve tissue.
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Abstract
In the past decade, aortic valve (AV) repair in children with cusp prolapse has comprised cusp plication, triangular resection and then extension with autopericardium. Although these techniques have been quite reproducible, durability of AV repair (AVRep) in children with a lack of valve tissue, has been challenging with the mean time to a 50% reoperation of 4,4 years (1). In this setting, cusp replacement may occasionally be quite beneficial to allow for aortic root growth and postponement AV replacement (AVR) methods can be safely used precluding their drawbacks for a time (2). We report a successful application of redo cusp replacement to pediatric patient applying cryopreserved decellularized glutaraldehyde-treated (CDGT) autopericardium.
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- europepmc
- last seen: 2026-05-20T01:45:00.602351+00:00
- unpaywall
- last seen: 2026-06-13T06:42:57.164913+00:00