Flow Tweezing of Anisotropic Magnetic Microrobots in a Dynamic Magnetic Trap for Active Retention and Localized Flow Sensing

Flow Tweezing of Anisotropic Magnetic Microrobots in a Dynamic Magnetic Trap for Active Retention and Localized Flow Sensing | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Flow Tweezing of Anisotropic Magnetic Microrobots in a Dynamic Magnetic Trap for Active Retention and Localized Flow Sensing Yuan Liu, Quanliang Cao, Haifeng Xu, Gungun Lin This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4173218/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Abstract Controlled manipulation of microscale robotic devices in complex fluidic networks is critical for various applications in biomedical endovascular sensing, lab-on-chip biochemical assays, and environmental monitoring. However, achieving controlled transport and active retention of microscale robots with flow sensing capability have proven challenging. Here, we report the dynamic tweezing of an anisotropic magnetic microrobot in a rotating magnetic trap for active retention and localized flow sensing under confined fluidic conditions. We reveal a series of unconventional motion modes and dynamics of the microrobot transporting in a confined fluidic flow, which manifest themselves as transitions from on-trap centre rolling to large-area revolution and off-trap centre rolling with varying rotating frequencies. By retaining the robot within the magnetic trap and its motion modulated by the field frequency, the off-centre rolling of the microrobot endows a crucial localized flow sensing capabilities, including flow rate and flow direction determination. The magnetic microrobot serves as a mobile platform for measuring the flow profile along a curved channel, mimicking a blood vessel. Our findings unlock a new strategy to determine local magnetic tweezing force profile and flow conditions in arbitrary flow channels, revealing strong potential for microfluidics, chemical reactors, and in-vivo endovascular flow measurement. Mechanical Engineering Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4173218","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":285217404,"identity":"2d6512f9-b44a-470c-8a30-48bc15caafe1","order_by":0,"name":"Yuan Liu","email":"","orcid":"","institution":"Shenzhen Institutes of Advanced Technology","correspondingAuthor":false,"prefix":"","firstName":"Yuan","middleName":"","lastName":"Liu","suffix":""},{"id":285217405,"identity":"2e29f08f-91cb-40ee-bd01-c07ee34a2b10","order_by":1,"name":"Quanliang Cao","email":"","orcid":"","institution":"Huazhong University of Science and Technology","correspondingAuthor":false,"prefix":"","firstName":"Quanliang","middleName":"","lastName":"Cao","suffix":""},{"id":285217406,"identity":"c189120f-2ac7-4e98-a097-d5b9be91d0d7","order_by":2,"name":"Haifeng Xu","email":"","orcid":"","institution":"Shenzhen Institutes of Advanced Technology","correspondingAuthor":false,"prefix":"","firstName":"Haifeng","middleName":"","lastName":"Xu","suffix":""},{"id":285217407,"identity":"971c2465-5cfa-46a1-9fc7-5731c2a97d34","order_by":3,"name":"Gungun Lin","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA5UlEQVRIie3OsQrCMBCA4SuFTG3nk4p9hUpAFH0Qx4jg1Dq72SkuPoCCvoOTOEYcXHTPKoKLFQqCix2MqGvI6JCfDAncxwXAZvvjqgRc8bkKQ+IRIOwzbUzUic1I1E13V38DXhBOH2FRQi2QzLl7GlKXw0HbP6iPVY9r3HKgFcncUEtmSYP6XBFMFcmgt5IMTElyQVHCWBH3qSMRJvT8JQQFARZLRrRbYi9vOEuOigxo88ixPj+ceGuh2zJJaHHjnVo065/kqOxEwb6/k7luiwCCAPh7vy9OpgFqSwZuoZ2w2Ww22wsobkUI1WYxugAAAABJRU5ErkJggg==","orcid":"","institution":"University of Technology Sydney","correspondingAuthor":true,"prefix":"","firstName":"Gungun","middleName":"","lastName":"Lin","suffix":""}],"badges":[],"createdAt":"2024-03-27 03:44:16","currentVersionCode":2,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-4173218/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-4173218/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":57101539,"identity":"62a7900a-07d7-4bc9-a0e0-e135de3de8ae","added_by":"auto","created_at":"2024-05-24 15:49:20","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":993959,"visible":true,"origin":"","legend":"","description":"","filename":"LOCMaintexts.pdf","url":"https://assets-eu.researchsquare.com/files/rs-4173218/v2_covered_aa472c94-aae4-4232-a602-cb7b1ac0699b.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003eFlow Tweezing of Anisotropic Magnetic Microrobots in a Dynamic Magnetic Trap for Active Retention and Localized Flow Sensing\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-4173218/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-4173218/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eControlled manipulation of microscale robotic devices in complex fluidic networks is critical for various applications in biomedical endovascular sensing, lab-on-chip biochemical assays, and environmental monitoring. 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