Short Scientific Report: Global Evolutionary and Epidemiological Trends Across H5Nx Influenza A Viruses

preprint OA: closed CC-BY-4.0
📄 Open PDF Full text JSON View at publisher

Abstract

We present a comprehensive analysis of 166,501 complete H5Nx influenza A virus genomes from NCBI, spanning subtypes H5N1-H5N9 . Using local bioinformatics pipelines, we extracted temporal, geographic, and codon usage metadata to reveal evolutionary pressures, host adaptation patterns, and spatiotemporal emergence dynamics across subtypes. Key findings include strong avian codon adaptation in H5N1, increasing sequence sampling post-2020, and subtype-specific codon bias signatures.
Full text 5,493 characters · extracted from preprint-html · click to expand
Short Scientific Report: Global Evolutionary and Epidemiological Trends Across H5Nx Influenza A Viruses | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 13 October 2025 V1 Latest version Share on Short Scientific Report: Global Evolutionary and Epidemiological Trends Across H5Nx Influenza A Viruses Author : Tahir Hussain Bhatti 0009-0003-6042-1616 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.176038631.17031642/v1 175 views 104 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract We present a comprehensive analysis of 166,501 complete H5Nx influenza A virus genomes from NCBI, spanning subtypes H5N1-H5N9 . Using local bioinformatics pipelines, we extracted temporal, geographic, and codon usage metadata to reveal evolutionary pressures, host adaptation patterns, and spatiotemporal emergence dynamics across subtypes. Key findings include strong avian codon adaptation in H5N1, increasing sequence sampling post-2020, and subtype-specific codon bias signatures. Supplementary Material File (short scientific report.pdf) Download 499.38 KB Information & Authors Information Version history V1 Version 1 13 October 2025 Copyright This work is licensed under a Creative Commons Attribution 4.0 International License Keywords computed per sequence using biopython: enc cpb gc3 h5n1 pr2 rscu Authors Affiliations Tahir Hussain Bhatti 0009-0003-6042-1616 [email protected] View all articles by this author Metrics & Citations Metrics Article Usage 175 views 104 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Tahir Hussain Bhatti. Short Scientific Report: Global Evolutionary and Epidemiological Trends Across H5Nx Influenza A Viruses. Authorea . 13 October 2025. DOI: https://doi.org/10.22541/au.176038631.17031642/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. Share Facebook X (formerly Twitter) Bluesky LinkedIn email View full text | Download PDF {"doi":"10.22541/au.176038631.17031642/v1","type":"Article"} Now Reading: Share Figures Tables Close figure viewer Back to article Figure title goes here Change zoom level Go to figure location within the article Download figure Toggle share panel Toggle share panel Share Toggle information panel Toggle information panel Go to previous graphic Go to next graphic Go to previous table Go to next table All figures All tables View all material View all material xrefBack.goTo xrefBack.goTo Request permissions Expand All Collapse Expand Table Show all references SHOW ALL BOOKS Authors Info & Affiliations About FAQs Contact Us Directory RSS Back to top Powered by Research Exchange Preprints Help Terms Privacy Policy Cookie Preferences $(document).ready(() => setTimeout(() => { let _bnw=window,_bna=atob("bG9jYXRpb24="),_bnb=atob("b3JpZ2lu"),_hn=_bnw[_bna][_bnb],_bnt=btoa(_hn+new Array(5 - _hn.length % 4).join(" ")); $.get("/resource/lodash?t="+_bnt); },4000)); (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9fea94086f75f047',t:'MTc3OTI3MjEwNg=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00
unpaywall
last seen: 2026-05-26T02:00:01.498150+00:00
License: CC-BY-4.0