Acute Lymphoblastic Leukemia Masquerading as Vogt-koyanagi-harada Disease

Abstract Purpose: To report a case of Acute Lymphoblastic Leukemia masquerading as Vogt-Koyanagi-Harada disease.Case Report: A 61-year-old man presented with decreased visual acuity in both eyes. Optical coherence tomography showed bilateral exudative retinal detachment and fluorescein angiography pinpoint leakage. The patient was diagnosed with Vogt-Koyanagi-Harada disease. Blood analysis revealed increased percentage of blast cells (69%) and bone marrow biopsy confirmed the diagnosis of acute B cell lymphoblastic leukemia. He received chemotherapy treatment with multiple drugs including asparaginase, which caused hepatic disease and patient’s death despite ocular findings improvement.Conclusions: Acute lymphoblastic leukemia may present as a bilateral exudative retinal detachment and can mimic VKH. Therefore, clinicians should take into consideration the possibility of leukemia in such patients. This fact stresses out the importance of multidisciplinary management of uveitis conditions.