Dolor - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis

Raúl Gómez
2021 · doi:10.5281/zenodo.15112957 · W6912139826
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study evaluated the therapeutic potential of RANK inhibition in mouse models of endometriosis-associated pain, using quantitative behavioral tests to measure unevoked pain.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

The paper evaluated the therapeutic potential of inhibiting RANK in optimized mouse models of endometriosis-associated pain and infertility, using quantitative behavioral tests that measured distance and time in Von Freyim, Balb-C, and CB57 strains. The study’s key findings (as reported in the paper’s available materials) addressed how RANK inhibition performed across these pain and reproductive-related endpoints. A major caveat is the reliance on specific animal model strains and behavioral paradigms as the basis for interpreting pain and infertility outcomes. This paper is centrally about endometriosis — it tests RANK inhibition in endometriosis-associated models of pain and infertility.

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Abstract

Dolor no evocado mediante test compartamentales cuantitativos de distancia y tiempo en modelo animal de ratón Von Freim, Balb-C y CB57 con endometriosis
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Published March 31, 2025 | Version 1 Dataset Open Dolor - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis Description Dolor no evocado mediante test compartamentales cuantitativos de distancia y tiempo en modelo animal de ratón Von Freim, Balb-C y CB57 con endometriosis Files Readme.txt Files (4.6 MB) | Name | Size | Download all | |---|---|---| | md5:7fc46ce94f91400750c43778f89592b5 | 1.6 MB | Download | | md5:fe6bb829ac490b7c7635d418595b9cc3 | 1.1 MB | Download | | md5:1ca8819f0594c0533a7a8868f6080667 | 2.3 kB | Preview Download | | md5:966c5c0628470738e3c717cd629bf3c8 | 282.6 kB | Download | | md5:59b35597587808f4c5de1c7ad91bc5f0 | 298.5 kB | Download | | md5:89f676f2570eecaee9c9d1bc5b675389 | 285.2 kB | Download | | md5:f5c13bfee1db4d56b13b8ad4b62facd7 | 199.7 kB | Download | | md5:5593785bc6a20a855bb845cd63f96236 | 206.8 kB | Download | | md5:bbef81845b63c3740b62792e010482ad | 282.6 kB | Download | | md5:7bac21df6f56c3815d88e40a8c35adcf | 304.1 kB | Download | Additional details Identifiers Funding - Instituto de Salud Carlos III - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis PI20/01835 Dates - Created - 2021-01-01Start of experimental phase - Created - 2024-12-31End of experimental phase

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endometriosis

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