Expectant management and hydrotubations in the treatment of endometriosis-associated infertility

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Expectant management of endometriosis-associated infertility yielded pregnancy rates of 24.4% overall, with higher rates for mild (52.9%) and moderate (25%) disease, while severe disease resulted in no pregnancies.

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Abstract

One hundred twenty-three infertility patients with laparoscopically documented endometriosis were managed expectantly for an interval of 1 to 25 months. Analysis revealed an overall pregnancy rate of 24.4% and a monthly fecundity rate (MFR) of 3.1%. Patients with mild disease had an overall pregnancy rate of 52.9% and an MFR of 5.7%. Women with moderate endometriosis did less well, but still demonstrated a pregnancy rate of 25% and an MFR of 3.2%. No pregnancies occurred with severe disease and expectant management. Postlaparoscopic hydrotubation was evaluated for its therapeutic effect with the use of multivariate analysis and maximum likelihood analysis. The results indicate that there is no decrease in the laparoscopy to conception interval, whereas a potential increase in cure rate cannot be adequately evaluated at this time.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Adult Endometriosis Fallopian Tube Patency Tests Female Fertility Humans Infertility, Female Infertility, Female Infertility, Female Laparoscopy Pregnancy Prognosis Therapeutic Irrigation

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Source provenance

europepmc
last seen: 2026-06-19T06:14:56.452680+00:00
pubmed
last seen: 2026-05-13T22:09:45.632124+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine