Geno reproductive toxicity and Ameliorative effects of sterols-rich Tribulus Terrestris against α-cypermethrin in male Wistar rats.

In rat testicular cells exposed to sub-lethal doses of α-cypermethrin (ACP), oxidative stress and genotoxicity were assessed. Additionally, the protective effects of Tribulus Terrestris sterols (TT) as antioxidants were compared with α-cypermethrin. A total of 40 adult male white rats were divided into four groups: a control group, α-cypermethrin (0.533 mg/kg bw),Tribulus Terrestris (100 mg/kg bw), and the group from a mixture of alphacypermethrin(0.533 mg/kg bw) and Tribulus terrestris (100mg/kg b.w). Analysis of the Tribulus terrestrisextract showed the presence of several sterols compounds that GC identified. The TT sterol compositions were Heneicosane (30.16%) and Tetracosane (27.99%), Cholesterol (1.14%), Stigmasterol (1.02%) and B-sterols (0.96%). The results showed that by raising antioxidantenzyme levels and lipid peroxidation in rat testicles, α-cypermethrin caused a significant amount of oxidative stress. Additionally, the findings showed that α-cypermethrin significantly reduced sperm count, sperm motility as a percentage of