Ieal Atresia and Total Colonic Hirschsprung Disease in a 36-week Neonate : Case Report

Abstract Intestinal atresia and Hirschsprung disease are two common causes of bowel obstruction in neonates, and simultaneous occurrence is rare. This report delineates a 36-week newborn with ileal atresia and total colonic Hirschsprung. A newborn male (gestational week 36; birth weight,2500 gram) was referred to our unit due to failure of meconium Passage during the first 48 hours after birth, abdominal distension, and bilious vomiting. Physical examination revealed a prominent abdomen, decreased bowel sounds, and an empty rectum in digital rectal examination. The abdominopelvic radiograph showed dilated intestinal loops. No gas was observed in the rectum. Intraoperative findings were: Type three Ileal atresia with classic V shape deformity in the mesentery just 10 mm proximal to the ileocecal valve. All parts of the large bowel were unused (microcolon). H&E examination of colonic biopsies revealed the absence of Ganglion cells in all parts of the large bowel.