Humic acid catalyzed solvent-free green protocol for synthesis of thioamide

An environmentally sustainable, green synthesis of thioamide through multi-component reaction (MCR) of aldehyde, amine and sulphur catalyzed by Humic acid in solvent-free condition at 100 o C. The key features of this protocol are use of humic acid, a greener, easily recyclable, easily available and almost unexplored catalyst and circumvention of noxious solvents that amplify the scope of the reaction. The proposed protocol also possesses tolerance to aromatic as well as aliphatic aldehydes and amines comprising variety electron donating and withdrawing functional groups.