Knowledge, attitudes, and practices associated with pharmacovigilance among healthcare professionals in a tertiary hospital in Ecuador

Knowledge, attitudes, and practices associated with pharmacovigilance among healthcare professionals in a tertiary hospital in Ecuador | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 1 March 2026 V1 Latest version Share on Knowledge, attitudes, and practices associated with pharmacovigilance among healthcare professionals in a tertiary hospital in Ecuador Authors : Candida García Gómez and Mónica Tarapués 0000-0003-3959-0944 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.177238095.50323032/v1 153 views 64 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Purpose: Under-reporting of suspected adverse drug reactions (ADRs) limits the performance of pharmacovigilance systems. This study assessed knowledge, attitudes, practices, and perceived barriers related to pharmacovigilance and ADR reporting among healthcare professionals in a tertiary hospital in Ecuador. Methods: An observational, descriptive, cross-sectional survey was conducted in inpatient clinical areas of a tertiary hospital in Cuenca, Ecuador (April–June 2024). A validated questionnaire was translated into Spanish and culturally adapted. The survey was administered in person, anonymized, and analyzed using descriptive statistics. Results: In total, 104 healthcare professionals participated (39 physicians, 15 pharmacists, 50 nurses). Knowledge and attitudes were generally favorable; however, practice was limited, with most respondents reporting no ADRs in the preceding year. Only 43% (45/104) reported knowing the hospital pharmacovigilance contact point, and 46% (48/104) believed that a single ADR report has no impact. The most frequently cited barriers were increased workload related to reporting (57%), lack of time (49%), lack of a professional environment to discuss ADRs (47%), and insufficient knowledge to identify ADRs (46%). A high causality certainty threshold was common (73% agreed that complete certainty is required before reporting). Conclusions: Despite generally adequate knowledge and positive attitudes, suspected ADR reporting was suboptimal. Interventions combining continuous training (emphasizing suspicion-based reporting), workflow facilitation, clear reporting pathways, and feedback and motivational strategies may strengthen hospital pharmacovigilance. Supplementary Material File (pds-26-0222-file001.docx) Download 4.84 MB File (pds-26-0222-file002.pdf) Download 207.50 KB Information & Authors Information Version history V1 Version 1 01 March 2026 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords adverse drug reactions barriers ecuador knowledge-attitude-practice pharmacovigilance spontaneous reporting Authors Affiliations Candida García Gómez Universidad de Cuenca View all articles by this author Mónica Tarapués 0000-0003-3959-0944 [email protected] Universidad de Cuenca View all articles by this author Metrics & Citations Metrics Article Usage 153 views 64 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Candida García Gómez, Mónica Tarapués. Knowledge, attitudes, and practices associated with pharmacovigilance among healthcare professionals in a tertiary hospital in Ecuador. Authorea . 01 March 2026. DOI: https://doi.org/10.22541/au.177238095.50323032/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. 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