Exploratory Study of Minimally Invasive Therapy: Laser Ablation Combined with ADM Implantation in Recurrent Sacrococcygeal Pilonidal Disease

Exploratory Study of Minimally Invasive Therapy: Laser Ablation Combined with ADM Implantation in Recurrent Sacrococcygeal Pilonidal Disease | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Exploratory Study of Minimally Invasive Therapy: Laser Ablation Combined with ADM Implantation in Recurrent Sacrococcygeal Pilonidal Disease Zhicheng Li, Lei Jin, Jialin Qin, Zhenyi Wang, Jiong Wu This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6664942/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Purpose: Recurrent sacrococcygeal pilonidal disease (SPD) presents considerable challenges in clinical management. In recent years, minimally invasive techniques, such as laser ablation, have emerged as promising alternatives for treatment. Furthermore, the application of acellular dermal matrix (ADM) has demonstrated potential benefits in wound healing and tissue regeneration. This clinical study aims to assess the efficacy and safety of the combined approach of laser ablation and ADM in the management of recurrent SPD. Basic procedures: We retrospectively analyzed the data of our five patients who diagnosed with recurrent SPD between October 2023 and April 2024. All patients underwent laser ablation in conjunction with ADM placement. We recorded clinical outcomes, including the healing rate and recurrence rate, as well as surgical data. Postoperative pain was assessed using the visual analog scale (VAS), and we documented the time taken for patients to return to their regular work and daily activities. Main findings: A total of five patients underwent laser ablation combined with ADM. Patients experienced minimal postoperative pain. All patients satisfied with this surgery. Conclusion: This pilot study suggests laser ablation with ADM may be a viable minimally invasive option for recurrent SPD, showing favorable outcomes. Larger comparative studies are needed to validate these findings. Recurrent sacrococcygeal pilonidal disease Laser ablation Acellular dermal matrix surgery Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6664942","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":470559647,"identity":"b6487939-ce86-4978-8043-9db48dd19fa4","order_by":0,"name":"Zhicheng Li","email":"","orcid":"","institution":"Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine","correspondingAuthor":false,"prefix":"","firstName":"Zhicheng","middleName":"","lastName":"Li","suffix":""},{"id":470559651,"identity":"09396136-f943-4043-afca-6c5b9a9dfca4","order_by":1,"name":"Lei 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