Effects of Early Infant Nutrition on Aperiodic Neural Activity from 2 to 12 Months Using EEG Analysis

Effects of Early Infant Nutrition on Aperiodic Neural Activity from 2 to 12 Months Using EEG Analysis | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL Psychophysiology This is a preprint and has not been peer reviewed. Data may be preliminary. 13 March 2025 V1 Latest version Share on Effects of Early Infant Nutrition on Aperiodic Neural Activity from 2 to 12 Months Using EEG Analysis Authors : Dylan Gilbreath 0009-0000-5108-146X , Adam Andrews 0009-0006-7526-6251 , Darcy Hagood , Aline Andres , and Linda Larson-Prior 0000-0002-9334-048X [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.174185667.75846840/v1 270 views 115 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Neural development begins in gestation and continues throughout early life. The environmental effect of infant diet is a subject of increasing study as it is the caloric fuel which supports all developmental processes. Previous research in our group has found small but significant effects of nutrition on early cognitive developmental tests between children primarily fed human milk (BF), soy-based formula (SF), and dairy-based formula (MF) for the first 12 months of life. This investigation uses this same dataset: a study throughout infancy from 2 to 12 months of life. High-density electroencephalographic (EEG) recordings were taken at 2, 3, 4, 5, 6, 9, and 12 months of age using a five-minute silent video baseline. Using Specparam (formerly fitting oscillations and one-over-F or “FOOOF”), aperiodic activity was computed through a power spectral density (PSD) analysis for each session, which were then averaged per dietary group over left, right, and medial frontal and parietal regions of interest (ROIs) and one occipital ROI. Aperiodic activity is a potential marker of neuromaturation, as it is hypothesized to relate to excitatory/inhibitory (E/I) balance and structural development in GABAergic systems. Consistent with previous findings, the aperiodic exponent steadily decreased for the first five months before stabilizing. We found that this effect was largely independent of early infant diet. Supplementary Material File (aperiodic_exponent_spr_submission.3.2025docx.docx) Download 5.20 MB Information & Authors Information Version history V1 Version 1 13 March 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Psychophysiology Authors Affiliations Dylan Gilbreath 0009-0000-5108-146X USDA-ARS Arkansas Children's Nutrition Center View all articles by this author Adam Andrews 0009-0006-7526-6251 USDA-ARS Arkansas Children's Nutrition Center View all articles by this author Darcy Hagood USDA-ARS Arkansas Children's Nutrition Center View all articles by this author Aline Andres USDA-ARS Arkansas Children's Nutrition Center View all articles by this author Linda Larson-Prior 0000-0002-9334-048X [email protected] USDA-ARS Arkansas Children's Nutrition Center View all articles by this author Metrics & Citations Metrics Article Usage 270 views 115 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Dylan Gilbreath, Adam Andrews, Darcy Hagood, et al. Effects of Early Infant Nutrition on Aperiodic Neural Activity from 2 to 12 Months Using EEG Analysis. Authorea . 13 March 2025. DOI: https://doi.org/10.22541/au.174185667.75846840/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. 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