UNIQUE MOLECULAR MARKERS IN HUMAN ENDOMETRIOSIS: IMPLICATIONS FOR DIAGNOSIS AND THERAPY

Blumenthal RD, A. Taylor, Michael Samoszuk, D M Goldenberg
In: Reproductive Medicine Review · 2003 · vol. 11(2-3) , pp. 105–119 · doi:10.1017/s096227990400105x · W2051736328
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-13 ⓘ

This paper explores unique molecular markers in endometriosis, a common, benign disease affecting reproductive-aged women and a significant cause of infertility.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This paper reviews endometriosis as a benign, sometimes progressive condition in which uterine-lining tissue spreads by local invasion or via blood vessels to distant sites, affecting an estimated 10–20% of women aged 30–40 and a substantial fraction of infertile women (30–45%). It frames the need for unique molecular markers by linking endometriosis prevalence and variability of symptoms to challenges in diagnosis and to potential avenues for therapy. A stated limitation is that the excerpt provides no original experimental data (it is presented as a review-style piece with limited bibliographic detail), so specific marker performance or validation criteria are not described here. This paper is centrally about endometriosis — it discusses the disease’s biology and the rationale for unique molecular markers to support diagnosis and therapy.

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Abstract

Endometriosis is a benign and often progressive disease in which tissue originating in the uterine lining spreads locally by direct invasion, or through the blood vessels to distal sites. The disorder affects as many as 10–20% of women aged 30–40, although many women remain asymptomatic. Between 30% and 45% of infertile women are diagnosed with endometriosis.
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No CrossRef data available. Published online by Cambridge University Press: 25 January 2005 Endometriosis is a benign and often progressive disease in which tissue originating in the uterine lining spreads locally by direct invasion, or through the blood vessels to distal sites. The disorder affects as many as 10–20% of women aged 30–40, although many women remain asymptomatic. Between 30% and 45% of infertile women are diagnosed with endometriosis. - Type - Research Article - Information - Copyright - © 2004 Cambridge University Press First published 20 November 2001 in Expert Reviews in Molecular Medicine: http://www.expertreviews.org/01003763h.htm Updated: 22 March 2004

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endometriosis

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