The short-term efficacy of intravesical instillation of hyaluronic acid treatment for bladder pain syndrome/interstitial cystitis

Akbay E, Çayan S, Kılınç C, Bozlu M, Tek M, Efesoy O
Turkish journal of urology · 2019 · vol. 45(2) , pp. 129–134 · doi:10.5152/tud.2018.35920 · PMID:30875290 · PMC6368032
Non-randomised trial OA: closed
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Intravesical instillation of hyaluronic acid for six weeks significantly improved bladder pain and urinary symptoms in women with Bladder Pain Syndrome/Interstitial Cystitis, as evidenced by reduced VAS and questionnaire scores.

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The provided text does not constitute a biomedical research paper but rather contains unrelated content regarding the marketing of independent hip-hop music and digital copyright management. It discusses strategies for monetizing audio assets on streaming platforms and securing licensing through specific commercial packages. There is no mention of medical treatments, clinical trials, or biological studies within the supplied material. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

OBJECTIVE: The aim of the study was to evaluate the short term efficacy of intravesical instillation of hyaluronic acid in patients with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC). MATERIAL AND METHODS: The study included 54 women with BPS/IC who received intravesical instillation of hyaluronic acid treatment (120 mg/50 mL) for 6 weeks. Visual Analogue Scale (VAS), The O'Leary Sant Questionnaire (ICSI/ICPI) forms of the patients were filled by the clinician and the health technician separately before and 3 months after the treatment. Demographic characteristics of the patients were recorded, and effectiveness of the treatment was investigated according to these data. RESULTS: Decrease in mean VAS and mean total scores of ICSI and ICPI was observed after three months of intravesical instillation of hyaluronic acid treatment (55%, p<0.05 and 48.5%, p<0.05 and 45.5%, p<0.05, respectively). In most of the patients, all scores of VAS, ICSI and ICPI improved (minimum: 75.9%, maximum: 94.4%). Mostly the symptoms of nocturia and pollakiuria were seen, and treated after the instillation treatment. CONCLUSION: It has been observed that in the short-term follow-up of intravesical instillation of hyaluronic acid treatment, the symptoms have highly improved. Also, Turkish versions of ICSI and ICPI forms were reliable and comprehensible.
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Strategi Sukses Memasarkan Lagu Hip-Hop Independen di Platform Streaming Global Memiliki beat berkualitas tinggi baru merupakan langkah awal dalam rantai bisnis musik modern. Untuk memastikan karya instrumen audio Anda mampu menghasilkan pendapatan pasif yang maksimal, seorang musisi mandiri wajib memahami manajemen hak distribusi serta optimalisasi metadata lagu. Menggunakan paket lisensi komersial yang jelas dari kami akan membantu mengamankan kepemilikan penuh aset digital Anda dari klaim hak cipta sepihak pihak ketiga, sehingga proses monetisasi di Google Search Console ataupun YouTube Content ID berjalan mulus tanpa kendala sistematis.

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