Investigation of Aloe Vera Mediated ZnO-β-CD Nanoparticles for Photocatalysis & Antimicrobial Applications

Investigation of Aloe Vera Mediated ZnO-β-CD Nanoparticles for Photocatalysis & Antimicrobial Applications | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Investigation of Aloe Vera Mediated ZnO-β-CD Nanoparticles for Photocatalysis & Antimicrobial Applications Arti Hadap, Vishal R Panse, Serhii Tereshchuk This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6003513/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 02 Jul, 2025 Read the published version in Scientific Reports → Version 1 posted 12 You are reading this latest preprint version Abstract This study presents the formation of Al based ZnO-β-cyclodextrin nano composite, by the green synthesis of ZnO nano particles from aloe vera (Al) plant extract, functionalized with β-cyclodextrin (β-CD). UV-Visible spectroscopy, Fourier transform infrared (FTIR), X-ray diffraction (XRD), Field emission electron microscopy (FESEM), and band gap energy measurement, were used to analyse the functionalized zinc oxide (ZnO) with β-CD nano composite. Present work involved the photocatalytic degradation of methylene blue (MB) dye as a model substrate used Al based ZnO- β-cyclodextrin nano composite where Al-based ZnO-NPs was worthily catalysis due to their unique bandgap (3.0eV) and β-cyclodextrin with ZnO, electron-hole recombination takes places very easily. At 6 pH, MB aqueous solution lose its blue colour after 160 minutes. Gram-positive bacteria S. aureus, gram-negative bacteria E. coli, and the fungus strain A. nigerwere all successfully combatted by the antibacterial activity. In presence of light and air, Al based ZnO-β-cyclodextrin nanocomposite generates singlet oxygen (O2*-) and hydrogen oxide radical (-OH*) which inhibit the growth of cells of bacterial and fungal strains. Although it was less hazardous and did not show negative effects on the development of healthy cells. Biological sciences/Microbiology Physical sciences/Materials science Physical sciences/Nanoscience and technology Green synthesis Aloe vera ZnO-β-cyclodextrin nano composite photocatalysis antibacterial antifungal Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 02 Jul, 2025 Read the published version in Scientific Reports → Version 1 posted Editorial decision: Revision requested 05 Mar, 2025 Reviews received at journal 05 Mar, 2025 Reviews received at journal 04 Mar, 2025 Reviews received at journal 27 Feb, 2025 Reviewers agreed at journal 24 Feb, 2025 Reviewers agreed at journal 23 Feb, 2025 Reviewers agreed at journal 22 Feb, 2025 Reviewers invited by journal 21 Feb, 2025 Editor assigned by journal 19 Feb, 2025 Editor invited by journal 19 Feb, 2025 Submission checks completed at journal 19 Feb, 2025 First submitted to journal 10 Feb, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6003513","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":418086263,"identity":"0087d271-3e7b-4be2-8e05-100bb112cd74","order_by":0,"name":"Arti Hadap","email":"","orcid":"","institution":"SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Deemed-to-University","correspondingAuthor":false,"prefix":"","firstName":"Arti","middleName":"","lastName":"Hadap","suffix":""},{"id":418086264,"identity":"377b92ca-a5de-402f-93bc-dcd5ee917b3c","order_by":1,"name":"Vishal R Panse","email":"","orcid":"","institution":"Late B.S. Arts, Prof. N.G. Sci \u0026 A.G. Commerce College","correspondingAuthor":false,"prefix":"","firstName":"Vishal","middleName":"R","lastName":"Panse","suffix":""},{"id":418086265,"identity":"7ebb3225-6d8f-4ef6-9754-52c99c45868b","order_by":2,"name":"Serhii Tereshchuk","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA9ElEQVRIiWNgGAWjYFACxgYogwfIrADSzMwNuFXDtByAazkD0gI3BA+Aa2lsQ7EXO5BvYG5g/lBxT06+/ewxyZnzaqP524FaflRsw6nF4ADIYWeKjQ3O5KVJbtx2PHfGYcYGxp4zt3FrATnjYFtC4gYJHjPJh9uO5TYAtTAztuHWIt8A0vIvoX7+DJCWOcdy5xPSwgBy2MGGhASGG0AtGxtqcjcQ0mIAVHDgzLEEww1ncowtZxw7kLsRKHIQn1/k29sfPqioSZCXbz9jeLOnpi533vnDBx/8qMDjMGZYtEDAYYhrcavHBHWkKB4Fo2AUjIIRAgAYil2shXsaEwAAAABJRU5ErkJggg==","orcid":"","institution":"Pavlo Tychyna Uman State Pedagogical University","correspondingAuthor":true,"prefix":"","firstName":"Serhii","middleName":"","lastName":"Tereshchuk","suffix":""}],"badges":[],"createdAt":"2025-02-11 04:23:26","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-6003513/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6003513/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1038/s41598-025-05231-6","type":"published","date":"2025-07-02T15:57:18+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":86179174,"identity":"85a129f2-6ee9-4c2b-bbc5-67ed843aebd6","added_by":"auto","created_at":"2025-07-07 16:16:44","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1383384,"visible":true,"origin":"","legend":"","description":"","filename":"scientificreports.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6003513/v1_covered_e548d9ed-7a55-4809-a241-c086c157d1f4.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Investigation of Aloe Vera Mediated ZnO-β-CD Nanoparticles for Photocatalysis \u0026 Antimicrobial Applications","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Green synthesis, Aloe vera, ZnO-β-cyclodextrin nano composite, photocatalysis, antibacterial, antifungal","lastPublishedDoi":"10.21203/rs.3.rs-6003513/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6003513/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study presents the formation of Al based ZnO-β-cyclodextrin nano composite, by the green synthesis of ZnO nano particles from aloe vera (Al) plant extract, functionalized with β-cyclodextrin (β-CD). UV-Visible spectroscopy, Fourier transform infrared (FTIR), X-ray diffraction (XRD), Field emission electron microscopy (FESEM), and band gap energy measurement, were used to analyse the functionalized zinc oxide (ZnO) with β-CD nano composite. Present work involved the photocatalytic degradation of methylene blue (MB) dye as a model substrate used Al based ZnO- β-cyclodextrin nano composite where Al-based ZnO-NPs was worthily catalysis due to their unique bandgap (3.0eV) and β-cyclodextrin with ZnO, electron-hole recombination takes places very easily. At 6 pH, MB aqueous solution lose its blue colour after 160 minutes. Gram-positive bacteria S. aureus, gram-negative bacteria E. coli, and the fungus strain A. nigerwere all successfully combatted by the antibacterial activity. In presence of light and air, Al based ZnO-β-cyclodextrin nanocomposite generates singlet oxygen (O2*-) and hydrogen oxide radical (-OH*) which inhibit the growth of cells of bacterial and fungal strains. Although it was less hazardous and did not show negative effects on the development of healthy cells.\u003c/p\u003e","manuscriptTitle":"Investigation of Aloe Vera Mediated ZnO-β-CD Nanoparticles for Photocatalysis \u0026amp; Antimicrobial Applications","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-02-21 13:49:59","doi":"10.21203/rs.3.rs-6003513/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-03-05T13:40:39+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-03-05T06:51:03+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-03-04T07:14:05+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-02-27T05:52:38+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"303985640690141844471916804337096612822","date":"2025-02-24T05:19:12+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"297608944335993536980486354075276882899","date":"2025-02-23T05:44:53+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"173499983222304705404315653408579179259","date":"2025-02-22T05:05:46+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-02-22T03:34:35+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-02-19T14:32:02+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-02-19T13:53:13+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-02-19T06:18:56+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2025-02-11T04:17:37+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"a9f8154a-927c-4157-a665-22b17434ff1f","owner":[],"postedDate":"February 21st, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":44577352,"name":"Biological sciences/Microbiology"},{"id":44577353,"name":"Physical sciences/Materials science"},{"id":44577354,"name":"Physical sciences/Nanoscience and technology"}],"tags":[],"updatedAt":"2025-07-07T16:06:48+00:00","versionOfRecord":{"articleIdentity":"rs-6003513","link":"https://doi.org/10.1038/s41598-025-05231-6","journal":{"identity":"scientific-reports","isVorOnly":false,"title":"Scientific Reports"},"publishedOn":"2025-07-02 15:57:18","publishedOnDateReadable":"July 2nd, 2025"},"versionCreatedAt":"2025-02-21 13:49:59","video":"","vorDoi":"10.1038/s41598-025-05231-6","vorDoiUrl":"https://doi.org/10.1038/s41598-025-05231-6","workflowStages":[]},"version":"v1","identity":"rs-6003513","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6003513","identity":"rs-6003513","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}