Combined transurethral approach with Versapoint® and laparoscopic treatment in the management of bladder endometriosis: technique and 12 months follow-up

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This study evaluated a combined transurethral Versapoint® and laparoscopic technique for bladder endometriosis in 12 women, finding it safe with low complication rates and symptom resolution at 12 months.

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AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

The paper describes a prospective observational study of 12 women with symptomatic bladder endometriosis, evaluating a combined approach that uses cystoscopy-guided transurethral delimitation and penetration with a bipolar Versapoint® electrode, followed by laparoscopic excision and bladder-hole repair with a continuous two-layer suture. The key reported findings were that operating times ranged from 115 to 167 minutes with blood loss of 10 to 200 ml, with no conversions to laparotomy or intraoperative complications and no dysuria or hematuria at 12-month follow-up, except for one case of persistent suprapubic pelvic pain. The authors’ limitation is the small sample size and observational design with follow-up limited to 12 months. This paper is centrally about endometriosis — it focuses specifically on a new combined transurethral (Versapoint®) plus laparoscopic technique for bladder endometriosis with 12-month outcomes.

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Abstract

BackgroundWhen endometriosis infiltrates more than 5 mm beneath the peritoneum it is called deeply infiltrating endometriosis and may involve the bladder. Only 1-2% of women with endometriosis have urinary involvement, mainly in the bladder. Resectoscopic transurethral resection alone is no longer recommended because of the surgical risks and recurrence. Usually surgeons prefer a laparotomy or laparoscopic approach depending on nodule localization and personal skill. We describe a new combined transurethral approach with Versapoint(®) and laparoscopic technique in the management of bladder endometriosis and the 12-month follow-up.MethodsWe performed a prospective observational study of 12 women affected by symptomatic bladder endometriosis at the University Hospital of Padova. We utilized a transurethral approach using a 5.2-mm endoscope with a 0.6-mm-diameter bipolar electrode (Gynecare Versapoint(®)). We delimited just the edges of the lesion via cystoscopy, penetrating transmurally at 3 or 9 o'clock without trespassing into the bladder peritoneum. Then, starting from the lateral bladder hole, we excised the lesion by laparoscopy with Harmonic ACE(®). The bladder hole was repaired with a continuous 3-0 monofilament two-layer suture.ResultsOperating time ranged from 115 to 167 min and mean blood loss ranged from 10 to 200 ml. No conversion to laparotomy and no intraoperative complications occurred. No dysuria or hematuria were present at follow-up. There was one case of persistent suprapubic pelvic pain at the 12-month follow-up.ConclusionsA combined transurethral approach with Versapoint(®) and laparoscopic treatment is a safe and easy technique for the management of bladder endometriosis, with low risks and good resolution of symptoms.
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Abstract

Background When endometriosis infiltrates more than 5 mm beneath the peritoneum it is called deeply infiltrating endometriosis and may involve the bladder. Only 1–2% of women with endometriosis have urinary involvement, mainly in the bladder. Resectoscopic transurethral resection alone is no longer recommended because of the surgical risks and recurrence. Usually surgeons prefer a laparotomy or laparoscopic approach depending on nodule localization and personal skill. We describe a new combined transurethral approach with Versapoint® and laparoscopic technique in the management of bladder endometriosis and the 12-month follow-up.

Methods

We performed a prospective observational study of 12 women affected by symptomatic bladder endometriosis at the University Hospital of Padova. We utilized a transurethral approach using a 5.2-mm endoscope with a 0.6-mm-diameter bipolar electrode (Gynecare Versapoint®). We delimited just the edges of the lesion via cystoscopy, penetrating transmurally at 3 or 9 o’clock without trespassing into the bladder peritoneum. Then, starting from the lateral bladder hole, we excised the lesion by laparoscopy with Harmonic ACE®. The bladder hole was repaired with a continuous 3–0 monofilament two-layer suture.

Results

Operating time ranged from 115 to 167 min and mean blood loss ranged from 10 to 200 ml. No conversion to laparotomy and no intraoperative complications occurred. No dysuria or hematuria were present at follow-up. There was one case of persistent suprapubic pelvic pain at the 12-month follow-up.

Conclusions

A combined transurethral approach with Versapoint® and laparoscopic treatment is a safe and easy technique for the management of bladder endometriosis, with low risks and good resolution of symptoms. Similar content being viewed by others

References

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Condition tags

endometriosisbladder_endometriosis

MeSH descriptors

Electrosurgery Endometriosis Laparoscopy Urinary Bladder Diseases Adult Combined Modality Therapy Endometriosis Female Follow-Up Studies Humans Laparoscopy Middle Aged Prospective Studies Time Factors Urethra Urinary Bladder Diseases Urologic Surgical Procedures Urologic Surgical Procedures

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