Multi-focus image fusion based on dynamic threshold neural P systems and difference of gaussian clarity

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This paper studied multi-focus image fusion (MFIF), integrating multiple images of the same scene taken at different focal points to create a single all-in-focus image, using a decision-map approach. The authors propose an enhanced Multi-scale Gaussian Contrast Synergistic Dynamic Threshold Neural P system (MGCS-DTNP) that extracts gradient features via Gaussian contrast filtering, feeds them into a Dynamic Threshold Neural P system with spiking and diffusion-time parameters to generate an initial decision map, and then refines it with small-area removal and median filtering before reconstructing the fused image. Experiments on the Lytro and MFFW datasets report that MGCS-DTNP outperforms 12 existing algorithms across six evaluation metrics, but the study is limited to those benchmark datasets and does not address clinical or real-world imaging constraints beyond standard MFIF evaluation. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Abstract To address the limitations of optical lens depth of field and integrate complementary information, Multi-Focus Image Fusion merges multiple images of the same scene taken at different focal points into a fully clear image. Although decision-map methods are commonly used in MFIF, accurately defining boundaries between focused and defocused areas remains a challenge. The Dynamic Threshold Neural P system, a distributed parallel computing model inspired by the cross-cortical model. Using dynamic thresholds and spiking mechanisms, it enables us to improve discrimination between areas in focus and out of focus. Building an enhanced framework called the Multi-scale Gaussian Contrast Synergistic Dynamic Threshold Neural P System (MGCS-DTNP) has been proposed. This method employs Gaussian contrast filtering to extract gradient features, leveraging the fact that focused regions exhibit sharper gradients. These features serve as input stimuli to the DTNP system, generating an initial decision map based on diffusion time parameters. After post-processing with small-area removal and median filtering, a refined decision map is produced. The final fused image is reconstructed by integrating regions from the source images according to this map. Experiments on the Lytro and MFFW datasets demonstrate that MGCS-DTNP outperforms 12 existing algorithms across six evaluation metrics, showing superior visual quality and fusion performance.
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Multi-focus image fusion based on dynamic threshold neural P systems and difference of gaussian clarity | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Multi-focus image fusion based on dynamic threshold neural P systems and difference of gaussian clarity Xu-Jie Duan, Xiao-Ting Guo, Hong-Liang Wang, Xiu-Yuan Li This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7708149/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract To address the limitations of optical lens depth of field and integrate complementary information, Multi-Focus Image Fusion merges multiple images of the same scene taken at different focal points into a fully clear image. Although decision-map methods are commonly used in MFIF, accurately defining boundaries between focused and defocused areas remains a challenge. The Dynamic Threshold Neural P system, a distributed parallel computing model inspired by the cross-cortical model. Using dynamic thresholds and spiking mechanisms, it enables us to improve discrimination between areas in focus and out of focus. Building an enhanced framework called the Multi-scale Gaussian Contrast Synergistic Dynamic Threshold Neural P System (MGCS-DTNP) has been proposed. This method employs Gaussian contrast filtering to extract gradient features, leveraging the fact that focused regions exhibit sharper gradients. These features serve as input stimuli to the DTNP system, generating an initial decision map based on diffusion time parameters. After post-processing with small-area removal and median filtering, a refined decision map is produced. The final fused image is reconstructed by integrating regions from the source images according to this map. Experiments on the Lytro and MFFW datasets demonstrate that MGCS-DTNP outperforms 12 existing algorithms across six evaluation metrics, showing superior visual quality and fusion performance. Multi-focus image fusion Gaussian contrast filter function Clarity calculation Dynamic threshold neural P systems Decision map Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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P systems, Decision map","lastPublishedDoi":"10.21203/rs.3.rs-7708149/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7708149/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eTo address the limitations of optical lens depth of field and integrate complementary information, Multi-Focus Image Fusion merges multiple images of the same scene taken at different focal points into a fully clear image. Although decision-map methods are commonly used in MFIF, accurately defining boundaries between focused and defocused areas remains a challenge. The Dynamic Threshold Neural P system, a distributed parallel computing model inspired by the cross-cortical model. Using dynamic thresholds and spiking mechanisms, it enables us to improve discrimination between areas in focus and out of focus. Building an enhanced framework called the Multi-scale Gaussian Contrast Synergistic Dynamic Threshold Neural P System (MGCS-DTNP) has been proposed. This method employs Gaussian contrast filtering to extract gradient features, leveraging the fact that focused regions exhibit sharper gradients. These features serve as input stimuli to the DTNP system, generating an initial decision map based on diffusion time parameters. After post-processing with small-area removal and median filtering, a refined decision map is produced. The final fused image is reconstructed by integrating regions from the source images according to this map. Experiments on the Lytro and MFFW datasets demonstrate that MGCS-DTNP outperforms 12 existing algorithms across six evaluation metrics, showing superior visual quality and fusion performance.\u003c/p\u003e","manuscriptTitle":"Multi-focus image fusion based on dynamic threshold neural P systems and difference of gaussian clarity","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-10-09 08:30:07","doi":"10.21203/rs.3.rs-7708149/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"4bb8597b-cbd7-4658-b7e1-49bc98884c92","owner":[],"postedDate":"October 9th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-10-13T12:24:00+00:00","versionOfRecord":[],"versionCreatedAt":"2025-10-09 08:30:07","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-7708149","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7708149","identity":"rs-7708149","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

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