Small RNA Profiling in HTLV-1-infected Patient with Acute Adult T-cell Leukemia-Lymphoma at Diagnosis and After Maintenance Therapy: A Case Study
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This case study profiles small RNA expression in an acute adult T-cell leukemia-lymphoma patient at diagnosis and after maintenance therapy to correlate expression levels with treatment response.
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Abstract
Small RNAs (sRNA) are epigenetic regulators of essential biological processes that have been linked to the onset and progression of leukemia, including acute adult T-cell leukemia-lymphoma (ATLL) caused by the retrovirus Human T-lymphotropic virus type 1. Here, we describe the sRNA profile of a 30-year-old female with ATLL at diagnosis and after maintenance therapy, with the goal of correlating their expression levels with response to therapy.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-26T02:00:01.498150+00:00
License: CC-BY-4.0