Estimation of 192Ir production rates in wires from natural iridium-platinum in research reactors

Estimation of 192Ir production rates in wires from natural iridium-platinum in research reactors | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Estimation of 192 Ir production rates in wires from natural iridium-platinum in research reactors Paolo Tataje, Braulio Ticona This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6285255/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Iridium-192 is a crucial radionuclide extensively used in brachytherapy for cancer treatment. The accurate estimation of its production rate is essential for ensuring precise dosimetry and therapeutic efficacy. This study evaluates the production rate of 192 Ir in wires composed of natural iridium-platinum alloys when irradiated in research reactors. The methodology incorporates the Hϕgdahl convention, taking into account neutron flux distribution, cross-section data, self-shielding factors, and resonance integral estimations. Experimental validation is carried out through neutron activation analysis and gamma spectroscopy using a HPGe detector. The results demonstrate a strong correlation between theoretical calculations and experimental measurements, providing a reliable framework for optimizing 192 Ir production for medical applications. Nuclear Chemistry Nuclear Physics production rates Hϕgdahl convention iridium Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6285255","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":432547169,"identity":"3720eba5-a678-4615-9d9a-81159df127a2","order_by":0,"name":"Paolo Tataje","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA6klEQVRIiWNgGAWjYNACHgY5NigzgbBqNgbGBqAWY1K1MDAkNhCtxVy++fmDHzI26X3SzcceMPyyyWOQbj6AV4tlG5thYw9PWm6bzLF0A8a+tGIGmWP4bTI4xmDYwMNzOLdNIsdMgrHncGKDRI4BAS3sHxv/8PxPZ5PI/wbVkv+BgBYew2YengMJbBI5bBIMP8C24NUB9EtO4WwZnmRDoF/MJBIb0orZZI7hd5g58/ENH9/22MnLz25+JvHhj00ev3TzA/wOAxGMPUBCAogT24ARJYHfXRAtDD+gWhj+wBijYBSMglEwChAAAE/wQ7zWvTvdAAAAAElFTkSuQmCC","orcid":"https://orcid.org/0000-0003-4980-394X","institution":"Peruvian Institute of Nuclear Energy","correspondingAuthor":true,"prefix":"","firstName":"Paolo","middleName":"","lastName":"Tataje","suffix":""},{"id":432547170,"identity":"2ce670a3-246c-4f83-a7bb-f2a02602aa77","order_by":1,"name":"Braulio Ticona","email":"","orcid":"https://orcid.org/0000-0001-6195-3567","institution":"Peruvian Institute of Nuclear Energy","correspondingAuthor":false,"prefix":"","firstName":"Braulio","middleName":"","lastName":"Ticona","suffix":""}],"badges":[],"createdAt":"2025-03-22 19:28:58","currentVersionCode":1,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-6285255/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6285255/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":79149399,"identity":"24de5b32-fb86-43d0-ac02-8cea81249ffa","added_by":"auto","created_at":"2025-03-25 03:59:56","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":284859,"visible":true,"origin":"","legend":"","description":"","filename":"Estimationof192Irproductionratesinwires.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6285255/v1_covered_adc654b3-32c4-4ba6-ba88-9ba8789afc3a.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003eEstimation of \u003csup\u003e192\u003c/sup\u003eIr production rates in wires from natural iridium-platinum in research reactors\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"Peruvian Institute of Nuclear Energy","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"production rates, Hϕgdahl convention, iridium","lastPublishedDoi":"10.21203/rs.3.rs-6285255/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6285255/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eIridium-192 is a crucial radionuclide extensively used in brachytherapy for cancer treatment. 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