[Transvaginal echography in patients with postmenopausal metrorrhagia]

Minerva ginecologica · 1995 · vol. 47(9) , pp. 369–72 · PMID:8545037 · W116414607
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Transvaginal ultrasonography with a 5 mm cut-off demonstrated 87.5% sensitivity and 90.5% negative predictive value for detecting pathologic endometrium in postmenopausal patients with abnormal uterine bleeding, highlighting the need for biopsy despite thin endometrial measurements.

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Abstract

Forty-one postmenopausal patients with abnormal uterine bleeding were scheduled for endometrial sampling in a week from the measurement of endometrial thickness by transvaginal ultrasonography. If the cut-off limit was 5 mm, the endometrial thickness was correlated with the presence of pathologic endometrium with a sensitivity of 87.5%, a specificity of 76%, a positive predictive value of 70% and a negative predictive value of 90.5%. Endometrial hyperplasia and polyp represented the two false negative cases. Waiting for a study on a sufficiently large series, the authors think that also an endometrial thickness of a few millimeters doesn't justify the non-recourse to endometrial biopsy in the presence of repeated haemorrhagic episodes or specific risk factors.

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MeSH descriptors

Endometrial Hyperplasia Endometrial Neoplasms Postmenopause Uterine Hemorrhage Adult Aged Biopsy Endometrial Hyperplasia Endometrial Hyperplasia Endometrial Neoplasms Endometrial Neoplasms Endometrium Endometrium Female Humans Middle Aged Ultrasonography Uterine Hemorrhage Uterine Hemorrhage Vagina

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