DNA as a perfect quantum computer based on the quantum physics principle

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Abstract DNA is a complex multi-resolution molecule whose theoretical study is a challenge. Its intrinsic multiscale nature requires chemistry and quantum physics to understand the structure and quantum informatics to explain its operation as a perfect quantum computer. Here, we present theoretical results of DNA that allow a better description of its structure and the operation process in the transmission, coding, and decoding of genetic information. Aromaticity is explained by the oscillatory resonant quantum state of correlated electron and hole pairs due to the quantized molecular vibrational energy acting as an attractive force. The correlated pairs form a supercurrent in the nitrogenous bases in a single band π-molecular orbital (π-MO). The MO wave function (Φ) is assumed to be the linear combination of the n constituent atomic orbitals. The central Hydrogen bond between Adenine (A) and Thymine (T) or Guanine (G) and Cytosine (C) functions like an ideal Josephson Junction. The approach of a Josephson Effect between two superconductors is correctly described, as well as the condensation of the nitrogenous bases to obtain the two entangled quantum states that form the qubit. Combining the quantum state of the composite system with the classical information, RNA polymerase teleports one of the four Bell states. DNA is a perfect quantum computer.
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DNA as a perfect quantum computer based on the quantum physics principle | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article DNA as a perfect quantum computer based on the quantum physics principle Raul Riera Aroche, Yveth Marlene Ortiz García, Meylín Aymeé Martínez Arellano, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3830073/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract DNA is a complex multi-resolution molecule whose theoretical study is a challenge. Its intrinsic multiscale nature requires chemistry and quantum physics to understand the structure and quantum informatics to explain its operation as a perfect quantum computer. Here, we present theoretical results of DNA that allow a better description of its structure and the operation process in the transmission, coding, and decoding of genetic information. Aromaticity is explained by the oscillatory resonant quantum state of correlated electron and hole pairs due to the quantized molecular vibrational energy acting as an attractive force. The correlated pairs form a supercurrent in the nitrogenous bases in a single band π-molecular orbital (π-MO). The MO wave function (Φ) is assumed to be the linear combination of the n constituent atomic orbitals. The central Hydrogen bond between Adenine (A) and Thymine (T) or Guanine (G) and Cytosine (C) functions like an ideal Josephson Junction. The approach of a Josephson Effect between two superconductors is correctly described, as well as the condensation of the nitrogenous bases to obtain the two entangled quantum states that form the qubit. Combining the quantum state of the composite system with the classical information, RNA polymerase teleports one of the four Bell states. DNA is a perfect quantum computer. Biophysics DNA oscillatory resonant quantum states electron and hole pairs Josephson Junction qubit Figures Figure 1 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Full Text Additional Declarations The authors declare no competing interests. Table 1 is available in the Supplementary Files section. Supplementary Files 2.Table1.pdf Table 1. Zero momentum state (P= 0) in A-T and C-G base pairs condensate. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3830073","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":264825832,"identity":"3e342831-0fab-471b-b6ca-3d1c0301bdcc","order_by":0,"name":"Raul Riera Aroche","email":"","orcid":"https://orcid.org/0000-0002-3098-1378","institution":"Department of Research in Physics, University of Sonora","correspondingAuthor":false,"prefix":"","firstName":"Raul","middleName":"Riera","lastName":"Aroche","suffix":""},{"id":264826148,"identity":"91e2f066-1229-428b-ae38-09c81c2ab0aa","order_by":1,"name":"Yveth Marlene Ortiz García","email":"","orcid":"https://orcid.org/0000-0002-2874-8913","institution":"Research Institute of Dentistry, University of Guadalajara","correspondingAuthor":false,"prefix":"","firstName":"Yveth","middleName":"Marlene Ortiz","lastName":"García","suffix":""},{"id":264826203,"identity":"9cf3a53b-d4da-4ddb-9af4-f2318f91f668","order_by":2,"name":"Meylín Aymeé Martínez Arellano","email":"","orcid":"https://orcid.org/0000-0002-3136-155X","institution":"General Hospital of the State of Sonora","correspondingAuthor":false,"prefix":"","firstName":"Meylín","middleName":"Aymeé Martínez","lastName":"Arellano","suffix":""},{"id":264826514,"identity":"a7d68d7d-2fb4-4540-bd18-47800b705d85","order_by":3,"name":"Annie Riera Leal","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAABFUlEQVRIie3QMUvDQBTA8SeBTpFzfKXl8hVeOEgd/DB3FOySwUky2UihWep+4OBXCAhODhdcg3MGh3bp1CFdpEKhJurYw4yC9x/ulvvxHgfgcv3RDAA2l5cCXB04A+h1JScNIU/00w7kp2+icvMLYfd3hdk+n/NRVtwud9QTohqvl3UCPEiPE3x7lYVeoxiWahYuyOdRdTkKdQmCjGVMFdOLb1BpUHP0CUVUyWhwOgeVW0TQkr3BqWar7GNPpB715L0l0wfLYtQSMCgR1dzzSaoc468pEiyLhQ0pFgZDjavZYEhGYLm57usSw9xCeBWLemduAmTjYrtJDGfZ5Anr5CKw/diRzmR7Yuf3TcyykMvlcv3bPgFPQF48STi3pQAAAABJRU5ErkJggg==","orcid":"https://orcid.org/0000-0002-6499-656X","institution":"General Hospital of the State of Sonora","correspondingAuthor":true,"prefix":"","firstName":"Annie","middleName":"Riera","lastName":"Leal","suffix":""}],"badges":[],"createdAt":"2024-01-02 17:45:26","currentVersionCode":1,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-3830073/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-3830073/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":49239992,"identity":"b76d421a-67ad-4813-9b98-9eaf5be93166","added_by":"auto","created_at":"2024-01-05 18:18:53","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":66118,"visible":true,"origin":"","legend":"\u003cp\u003eSee image above for figure legend.\u003c/p\u003e","description":"","filename":"1.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/be9cea7f75bb41288739eb3b.jpg"},{"id":49239993,"identity":"ebb6f9c6-24d9-4705-ad65-6f6a0555b5a0","added_by":"auto","created_at":"2024-01-05 18:18:53","extension":"jpg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":650501,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe Nucleobases A, T, C, and G oscillatory resonant quantum state between electron and hole pairs\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003eA) The non-hybridized in-face 𝑝\u003csub\u003ez\u003c/sub\u003e orbitals overlap. A lone pair of delocalized electrons will participate in resonance with the double bond and form an extended 𝜋-system. B) Oscillatory resonant quantum states between electron and hole pairs to explain aromaticity in the nitrogenous bases.\u003c/p\u003e","description":"","filename":"Figure3.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/fb6ad4f1e40f8ed83d2a7cd0.jpg"},{"id":49238125,"identity":"d5686e41-6a57-4740-a95c-d7c1072c624d","added_by":"auto","created_at":"2024-01-05 18:10:52","extension":"jpg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":638970,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eJosephson Effect in A-T and C-G coordination complexes.\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA) The central H-bond (NH--N), connecting two canonical nitrogenous bases, constitutes the Josephson Junction. B) Tunnel Effect: 𝑒\u003csub\u003e1\u003c/sub\u003e crosses the Junction without losing energy and with the same momentum but the opposite sign. C) Oscillatory resonant quantum states between electron and hole pairs in N\u003csub\u003e1\u003c/sub\u003e\u0026nbsp;and N\u003csub\u003e3\u003c/sub\u003e\u0026nbsp;in-face 𝑝\u003csub\u003ez\u003c/sub\u003e orbitals.\u003c/p\u003e","description":"","filename":"Figure4.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/c6a9fd11ade0318e11d4a9aa.jpg"},{"id":49239990,"identity":"af539789-7aaa-4ab8-812d-a4caefbbf2f0","added_by":"auto","created_at":"2024-01-05 18:18:52","extension":"jpg","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":302646,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eMagnetic field in A-T and G-C coordination complexes.\u0026nbsp;\u003c/strong\u003eA continuous flow that generates the diamagnetic ring current since all possible ionic structures assist the electron flow. I\u003csub\u003eG\u0026nbsp;\u003c/sub\u003e(I\u003csub\u003eA\u003c/sub\u003e) current generates a magnetic field in the conductor with I\u003csub\u003eC\u0026nbsp;\u003c/sub\u003e(I\u003csub\u003eT\u003c/sub\u003e)\u0026nbsp;current,\u0026nbsp;represented by crosses that are lines of field forces entering the plane and producing the force F\u003csub\u003eCG\u003c/sub\u003e\u0026nbsp;(F\u003csub\u003eTA\u003c/sub\u003e) in the conductor I\u003csub\u003eC\u0026nbsp;\u003c/sub\u003e(I\u003csub\u003eT\u003c/sub\u003e)\u003csub\u003e.\u0026nbsp;\u003c/sub\u003eOn the other hand, the conductor with current I\u003csub\u003eC\u003c/sub\u003e\u0026nbsp;(I\u003csub\u003eT\u003c/sub\u003e) creates a magnetic field represented by balls, which means that the lines of forces leave the plane, creating the force F\u003csub\u003eGC\u003c/sub\u003e\u0026nbsp;(F\u003csub\u003eAT\u003c/sub\u003e) in the conductor with current I\u003csub\u003eG\u0026nbsp;\u003c/sub\u003e(I\u003csub\u003eA\u003c/sub\u003e).\u003c/p\u003e","description":"","filename":"Figure5.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/c4fa55663d814d1384d1f4cd.jpg"},{"id":49238128,"identity":"7df8d84f-2fac-41f9-b8b7-44ad70179f28","added_by":"auto","created_at":"2024-01-05 18:10:53","extension":"jpg","order_by":6,"title":"Figure 6","display":"","copyAsset":false,"role":"figure","size":547048,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eSymmetries of DNA canonical base pairs quantum informational cryptography. A)\u003c/strong\u003e Chemical structure of the nitrogenous bases, pyrimidines, and purines\u003cstrong\u003e. \u003c/strong\u003eB) A-T and C-G, in their mutual connection, have the same functional quantum state while retaining different structures and morphologies.\u003c/p\u003e","description":"","filename":"Figure6.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/0474c3e19db448c1b4154ec7.jpg"},{"id":49238130,"identity":"e8b4dbec-0d8e-4bb7-a123-6564602d1584","added_by":"auto","created_at":"2024-01-05 18:10:53","extension":"jpg","order_by":7,"title":"Figure 7","display":"","copyAsset":false,"role":"figure","size":391065,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe electric current is presented in a metallic solid, a semiconductor, and DNA. A) \u003c/strong\u003eCorrelated electron and hole pairs in a metallic conductor upon reaching the 𝑇\u003csub\u003e\u003cem\u003ec\u003c/em\u003e\u003c/sub\u003e. B) In a semiconductor, there is no pair formation. C) Oscillatory resonant quantum state between electron and hole pairs in DNA nucleobases.\u003c/p\u003e","description":"","filename":"Figure7.jpg","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/85ceb3e54f8f87736ad5dc9e.jpg"},{"id":49242961,"identity":"b92136d9-0977-4968-987a-2c695054af82","added_by":"auto","created_at":"2024-01-05 18:35:03","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1120450,"visible":true,"origin":"","legend":"","description":"","filename":"1.DNAasaperfectquantumcomputer.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1_covered_2b1d451a-67b5-46a4-afb0-f19ca3c05d40.pdf"},{"id":49241663,"identity":"32c0f8e7-54ee-4777-9763-5546bc2a17f4","added_by":"auto","created_at":"2024-01-05 18:26:52","extension":"pdf","order_by":2,"title":"","display":"","copyAsset":false,"role":"supplement","size":44879,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eTable 1. Zero momentum state (P= 0) in A-T and C-G base pairs condensate.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"2.Table1.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3830073/v1/72a38f21f19c2bca0ee3f447.pdf"}],"financialInterests":"\u003cp\u003eThe authors declare no competing interests.\u003c/p\u003e\n\u003cp\u003eTable 1 is available in the Supplementary Files section.\u003c/p\u003e","formattedTitle":"\u003cp\u003eDNA as a perfect quantum computer based on the quantum physics principle\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"Research and Higher Education Center of UNEPROP","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"DNA, oscillatory resonant quantum states, electron and hole pairs, Josephson Junction qubit","lastPublishedDoi":"10.21203/rs.3.rs-3830073/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3830073/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eDNA is a complex multi-resolution molecule whose theoretical study is a challenge. Its intrinsic multiscale nature requires chemistry and quantum physics to understand the structure and quantum informatics to explain its operation as a perfect quantum computer. Here, we present theoretical results of DNA that allow a better description of its structure and the operation process in the transmission, coding, and decoding of genetic information. Aromaticity is explained by the oscillatory resonant quantum state of correlated electron and hole pairs due to the quantized molecular vibrational energy acting as an attractive force. The correlated pairs form a supercurrent in the nitrogenous bases in a single band π-molecular orbital (π-MO). The MO wave function (Φ) is assumed to be the linear combination of the n constituent atomic orbitals. The central Hydrogen bond between Adenine (A) and Thymine (T) or Guanine (G) and Cytosine (C) functions like an ideal Josephson Junction. The approach of a Josephson Effect between two superconductors is correctly described, as well as the condensation of the nitrogenous bases to obtain the two entangled quantum states that form the qubit. Combining the quantum state of the composite system with the classical information, RNA polymerase teleports one of the four Bell states. 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