Public views on genetics and genetic testing of sudden unexplained death: A survey of the public in China

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We conducted a telephone follow-ups targeted 199 out-of-hospital cardiac arrest (OHCA) cases in Hangzhou, and a public survey included 536 respondents from various demographic groups, including emergency volunteers, housewives, IT practitioners, Cardiovascular patients' relatives, and drivers. The telephone follow-up revealed a low participation rate in genetic testing among survivors and victims' immediate relatives. The public survey indicated a general lack of awareness and knowledge about genetics and genetic testing for SCD. Significant differences in attitudes were observed based on demographic factors such as age, health insurance, and occupations. Many respondents expressed concerns about the implications of genetic testing and a general distrust in medical recommendations. The study highlights the urgent need for enhanced public education on the importance of genetic testing for SCD and the development of more effective communication strategies to address public concerns. Increasing awareness and understanding of the benefits of genetic testing could improve acceptance and participation, ultimately aiding in the prevention and management of SCD in China. Health sciences/Medical research/Genetics research Health sciences/Pathogenesis/Clinical genetics/Genetic testing Health sciences/Diseases/Cardiovascular diseases/Arrhythmias/Ventricular fibrillation Genetic testing Sudden unexplained death Whole Exome Sequencing (WES) Survey Public attitude Figures Figure 1 Introduction Sudden cardiac arrest (SCA) is a condition in which the heart stops beating, causing blood flow to the brain and vital organs to cease. This also contributes to the high mortality rate of cardiovascular diseases. The incidence varies across different regions or countries. The incidence of cardiovascular diseases in China was 41.8 per 100,000 individuals in 2005[ 1 , 2 ], doubling to 95.7 per 100,000 by 2020[ 3 ]. In comparison, Europe and the U.S. report a prevalence ranging between 50 and 100 cases per 100,000 individuals [ 4 , 5 ]. Among these diseases, coronary artery disease is most prevalent, leading to a rise in SCD, a substantial healthcare burden in China. Despite ongoing efforts like distributing automatic external defibrillators (AEDs) in public places, few policies and preventative measures have been implemented. According to studies, SCD accounts for over 750,707 deaths annually among China's citizens [ 3 ]. Coronary heart disease is a common cause of sudden cardiac death (SCD) in the elderly, while genetic factors are often responsible in younger individuals, particularly those with a family history of SCD. Advances in next-generation sequencing (NGS) have identified genes related to arrhythmias and cardiomyopathies, uncovering causes of previously unexplained SCD cases [ 6 – 8 ]. In young individuals, SCD is often linked to genetic causes, with conditions such as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), myocarditis, and various arrhythmogenic disorders like Brugada syndrome (BrS) and long-QT syndrome (LQTS)[ 9 , 10 ]. These genetic disorders, typically autosomal dominant, mean immediate relatives have a 50% risk of inheriting the pathogenic variant [ 11 ]. Therefore, genetic testing is crucial for survivors and their families, aiding in clarifying the SCD etiology, offering personalized medical treatments, and evaluating preventive strategies like the effectiveness of implantable defibrillators [ 12 ]. Guidelines from global bodies such as the American Heart Association and the European Society of Cardiology highlight the importance of genetic testing for inherited cardiovascular diseases [ 13 ], and the 2015 European society of cardiology (ESC) guidelines show the value of genetic screening for family members of SCD victims[ 14 ]. Similarly, expert consensus in China recommends genetic testing as per the Long-QT Syndrome and Hereditary Cardiomyopathy Clinical Practice Guidelines [ 15 ]. To investigate the molecular epidemiology of SCA in Hangzhou, The Hangzhou Emergency Center of Zhejiang Province launched a charity project from 2020 to 2022 to provide free genetic testing for individuals under 50 who experienced sudden unexplained deaths. However, a significant number of survivors and victims' immediate relatives expressed concerns or even opposition to genetic testing. This study aims to investigate the attitudes of SCD survivors, victims' relatives, and the public towards genetic testing through a comprehensive survey. There have been many genetic testing surveys since the completion of Human Genome Project, but initially, they were generally for geneticists or doctors [ 16 – 18 ], and some public surveys were for the special diseases, such as deafness [ 19 , 20 ]. The advent of NGS has reduced the cost of whole exome sequencing, promoting its clinical use, and surveys have been conducted globally [ 21 – 23 ], focusing mostly on reproductive health and supporting prenatal genetic testing to avoid birth defects. Few surveys have focused on cardiovascular issues, mainly conducted by direct-to-consumer health and insurance companies, and none specifically targeted SCD survivors or their families. Moreover, no questionnaire survey targeting SCD survivors or victims’ immediate family members. Survey methodology has evolved from traditional paper-and-pencil forms to email and, more recently, to popular mobile-based formats [ 21 , 24 ]. This study’s objectives are to explore the public's attitudes towards SCD genetic testing and to identify significant differences based on demographic factors. It will also investigate the concerns of individuals with negative attitudes and assess whether information dissemination can influence their choices. Materials and Methods Study design for telephone follow-up We conducted a retrospective study on 9585 OHCA cases of Hangzhou Emergency Center, between January 2015 and December 2021. We focused on the cases for telephone follow-up, the principles are as following: i). Under the age of 50. ii). Cardiac arrest, especially ventricular fibrillation. iii). Exclude clear causes, such as: car accident, suicide, homicide, coronary heart disease, cerebral infarction etc. Telephone follow-up We prepared two scripts for the telephone follow-up (See Supplemental Table 1 ). Study design for questionnaire survey A likert-scale written questionnaire was developed to gauge the public’s views on various topics related to the genetics [22,25-29], including knowledge of genetics and gene testing [30]; preferences among potential providers of gene testing; preferences among potential providers of SCD gene testing; and future expectations and concerns regarding SCD gene testing. This study was approved by the Ethics Committee of the Hangzhou Emergency Center. We adopted the currently popular mobile-based survey method by designing a website for the questionnaire [24,31], A QR code was generated to enable respondents to easily scan and complete the survey on their cell phones. Participants Convenience sampling was used to select participants, grouped as follows: i. First Aid Trainees: Participants from the Hangzhou Emergency Center's primary first aid training class, representing various societal sectors but all trained in SCD concepts and CPR. ii. General Population: Employees from nearby office buildings and housewives shopping, serving as the control group. iii. IT practitioners: Employees from Alibaba Group and similar companies in Hangzhou, characterized by young age, high salaries, intense work schedules ('996'), with frequent SCD cases. iv. Relatives of Cardiovascular Patients: Immediate family or caregivers of ICU and cardiovascular ward patients, likely decision-makers for future genetic testing for SCD. v. Ride-Hailing Drivers: Taxi and online car-hailing drivers, a high-risk group for SCD due to poor working conditions and irregular lifestyles. Eligibility Criteria: i). Aged 18 years or older ii). Ability to understand, speak Mandarin, and read Chinese. Quality Control: To ensure the quality of responses, a multiple-choice question about the respondent's age was included at both the beginning and end of the questionnaire. Inconsistent answers classified the questionnaire as invalid. Questionnaire contents The questionnaire consists of five parts: 1.Demographic Attributes: Nine questions on gender, age, weekly working hours, education level, occupations, annual income, medical insurance coverage, CPR training participation, and religious beliefs. [17,22,32,33]. 2. Attitudes Towards SCD: Four questions on: Awareness of SCD Response to professional consultation about SCD Attitude towards genetic testing for SCD in family/friends if recommended by a doctor Reasons for agreement, neutrality, or disagreement with genetic testing [34]. 3. Genetic Knowledge: Ten questions to assess respondents' genetic knowledge [30]. 4. Importance of Genetic Testing: Highlights known genetic conditions (e.g., hereditary deafness, ALS, thalassemia), includes brief educational segments on genetic aspects related to SCA. 5. Attitudes Post-Education: Repeats questions on attitudes towards genetic testing for SCD to gauge changes after exposure to educational content. The questionnaire draws from existing surveys while incorporating innovative designs such as educational passages on the genetic basis of SCD and a before-and-after approach to assess attitude changes. The counts for each of these groups are reported separately in Table 1 . Data analyses Once the respondents finish the questionnaire survey, we can export all the data from the website. p-Values of 0.05 and 0.01 were used for distinguishing between different levels of statistical significance. Statistical analysis of the study was performed using SAS version 9.4 (SAS Institute Inc., Cary, NC, USA). Data are presented as numbers and percentages and analyzed by chi-square test. An unconditional logistic regression model was used to calculate the odds ratio (OR) and 95% confidence intervals (CI) for the risk factors of choice of gene test in a manner of univariate or multivariate with stepwise selection. A two-sided P < 0.05 was considered statistically significant. Results Telephone follow-up results From 199 enrolled cases, the median age was 32±8.6 years, with 141 (71%) men. SCD incidents occurred at home (64 cases, 32.2%), workplaces (28 cases, 14%), and public places like subways and hotels (81 cases, 40.7%). There are 31(15.8%) survivors (labeled as 'Survivors') while and 168 (84.4%) victims (labeled as 'Victims') ( Table 2 ). Emergency calls: 36 (18%) made by immediate relatives, 26 by colleagues/friends (18 provided contact info). Among 69 public emergency calls, most callers either couldn’t recall the event or lacked contact information. Additionally, 68 calls were out of service or invalid. We contacted 10 survivors and 42 victims' relatives. Of the survivors, 8 were willing to participate, but only 3 completed genetic testing. For the victim's relatives, 11 were initially willing but only 1 participated in genetic testing. The rest declined for various reasons or did not provide a reason. Reasons for declining SCD genetic testing Survivor: " I have undergone a comprehensive heart ultrasound and other diagnostic tests. The doctor concluded that my heart is healthy. and my cardiac arrest was attributed to extreme fatigue ." " Nothing like this has happened in my family; my cardiac arrest definitely had nothing to do with genetics ." Victim’s Spouse (No Children): " He/She is my ex-boyfriend/ex-girlfriend, and I currently have no contact with his/her family. I hope to move on from this matter as soon as possible ." Victim’s Parents: " Our family has no history of similar situations. Both my spouse and I are in good health, so it's unlikely this is caused by genetic factors. There's no need for testing. " Victim’s Siblings: " There's no history of such conditions in our family. Our parents are also healthy, so it's unlikely this is genetic. Testing is unnecessary. " Victim’s Spouse (With Kids): " My child is currently very healthy, and we don't believe genetics play a role. We don't wish to undergo testing ." Lager scale public survey of knowledge and attitudes regarding SCD genetic testing After removing the invalid questionnaires, we received a total of 477 valid responses (The original survey data is presented in Supplemental Table 2 ). We use 'Willingness to undergo SCD genetic testing' (column P) as the independent variable (Responses of "agree" and "strongly agree" were categorized as “yes”=0, while all other responses were categorized as “no”=1). We perform univariate logistic regression analysis with other indicators as independent variables. Categorical variables are entered into the model as dummy variables. A total of 366 participants agreed to undergo SCD genetic testing, while 111 participants disagreed ( Table 3 ) Participants The results in Table 3 and Supplemental Table 3 reflect current trends in China. In the 'Gender' category, the IT practitioners show an almost equal male-female distribution, while drivers are predominantly male (95.8%). Emergency volunteers are mostly male (63.5% vs. 36.5%). Men are less willing to undergo SCD genetic testing (OR=1.356, 95% CI=0.876-2.122, p=0.176). Occupations Different occupations show significant differences in willingness for SCD genetic testing: emergency volunteers are the most willing, followed by cardiovascular patients’ relatives, with drivers, IT practitioners, and housewives showing less interest (p=0.004). Age In the IT practitioners, 95.4% of employees are under 35 years old, aligning with the '35-year unemployment line.' Educational attainment is high, with 97.7% of IT workers and 86.5% of emergency volunteers having higher education. The '35-50 years' group is most willing to undergo testing, while the '25-35 years' group is less willing (OR=0.550, 95% CI=0.313-0.967). Combining ages 36 and older: OR=0.506, 95% CI=0.309-0.826, p=0.015. Income An annual income exceeding 120k yuan was classified as high. Among different occupations, drivers had the lowest proportion in this category (15.3%), while emergency volunteers had the highest (44.4%). Regarding working hours, 12.7% of drivers reported working over 70 hours per week. The distribution of drivers working 40-50 hours, 50-60 hours, and 60-70 hours per week was 23.6%, 5.45%, and 12.73%, respectively. Notably, only 45.45% of drivers worked fewer than 40 hours per week ( Supplemental Table 3 ). We did not adjust income based on working hours, and high-income groups showed no significant difference in willingness to undergo SCD genetic testing (p = 0.167). Health Insurance Most respondents have medical insurance. However, 9.2% of IT workers and 12.5% of drivers do not. Additional commercial insurance is more common among emergency volunteers (27.8%). Willingness for testing increases with better insurance coverage (p-trend <0.001). Religious Beliefs Out of 477 respondents, 322 believe in science, while 12 are devout believers, 43 individuals chose 'keep secret,' others selected 'a little bit.' We included those ‘keep secret' in the 'religious beliefs' category for statistical analysis. 33.3% of individuals with 'religious beliefs' chose to refuse, whereas only 18.9% of those who 'trust science' opted to refuse, indicating that individuals who trust science are more willing to undergo SCD genetic testing (OR=0.467, 95% CI=0.3-0.727, p <0.001). Awareness of SCD 337 respondents have only seen SCD in the news. 18 have experienced it among family members, with 8 from the 'emergency volunteer' group strongly supporting genetic testing. Additionally, 5 respondents stated they were 'uncertain but willing to cooperate with doctors.' 80 have witnessed SCD among colleagues or friends; 40 are willing to cooperate with doctors. Willingness for Genetic Testing 366 respondents are willing to undergo genetic testing, highest among emergency volunteers (87.3%) and lowest among drivers (66.7%). Significant differences exist among groups, with the strongest willingness shown by those who 'only saw it in the news' (OR=0.372, 95% CI=0.19-0.727). When combining those with personal experiences related to SCD, the odds ratio is OR=0.531, 95% CI=0.248-1.138, p=0.025. Participant knowledge was assessed through 10 questions ( Supplemental Table 4 ), with correct response rates ranging from 54.2% to 66.2%. Nine questions were true/false, and one was multiple-choice. Influenced by traditional Chinese 'patrilineal society' and similar ideologies, such as those in the question 'People share more genes with their paternal cousins than their maternal cousins,' —over 60% of 'housewives' incorrectly responded "True." Furthermore, even among IT practitioners and emergency volunteers, the correct response rates were only 72.8% and 59.5%, respectively, indicating that higher education in China often overlooks medical genetics. For instance, the question "Every trait is controlled by a specific single gene" had the lowest correct response rates, ranging from 24% to 47%. Common misconceptions regarding 'genetic diseases' requiring a family history were also prevalent. Scores ≤6 were considered low, and ≥7 high. No significant differences were found between these groups (p=0.608, See Table 3 ). Comparative willingness for SCD testing among different occupations Groups The study conducted a comparative analysis of the willingness to undergo genetic testing, the actual participation in genetic testing, and the statistical evaluation of genetic assessment across five different occupations groups. The results indicate that emergency volunteers exhibited significantly higher levels in all aspects compared to other groups, including a greater willingness to undergo genetic testing (Emergency volunteers VS Non-Emergency volunteers, p=0.00419), a higher number of volunteers who have undergone genetic testing (p=0.002583), and elevated scores in genetic assessments (See Figure 1 , Supplementary Tables 5 and 6 ). Reasons for supporting SCD genetic testing (n= 337) 1. “ Early intervention and treatment for the high-risk members” . 247 (73.2%) 2. “ Can help to identify the cause of SCD”. 230 (68.2%) 3. “ Informed family planning to prevent the next child carrying the pathogenic mutation”. 228 (67.7%) 4. “I willing to support the SCD genetic research”. 201 (59.6%) Reasons for un-supporting SCD genetic testing (n=26) 1. “ If I tested high risk, can’t climb mountains, can't play ball, can't do strenuous exercise, if only in this way can prevent sudden death, what is the meaning of life like this”. 13 (50%) 2. “I am health now, and I don’t want to know my SCD risk”, “Knowing a result that cannot be changed is worse than not knowing”. 9 (34.6%) 3. “ The genetic testing will cause stress to my kids”. 7 (26.9%) 4. “If I tested high risk, it would cause trouble for my insurance”, “I / My kids will be discriminated by others in case of the positive test results”. 4 (15.4%) 5. “I don’t think the SCD is genetically related”, “I think SCD is scientifically unclear” . 2 (7.7%) Multivariate analysis Considering the relatively small sample size of this study, we reorganized the significant indicators from Table 2 for multivariate analysis. Age was categorized into two groups: under 35 and 35 and over. Occupation was divided into emergency volunteers and other categories. Insurance status was classified as uninsured and insured. The K variable was categorized into those who had not experienced or paid attention to similar news and those who had seen or heard about it. Using the willingness to undergo genetic testing as the dependent variable (yes=0, no=1), we employed stepwise selection to construct a logistic regression model with these indicators as independent variables. The statistically significant indicators identified were Occupations, Religious beliefs ( Supplemental Table 7 ) Attitude change after science education Among the 477 participants in the survey, 111 initially disagreed with genetic testing. After three guided multiple-choice questions and a segment of educational content on the subject, 47 of these individuals changed their stance to agree ( Table 4 ). Using whether the participant changed to agree with genetic testing as the dependent variable (yes=1, no=0), logistic regression analysis was performed with the following indicators as independent variables. All statistically significant indicators were included in the model, and stepwise logistic regression analysis was conducted. Ultimately, only column AF (Do you think these deaf, ALS, colorblind, and hemophilia patients should undergo genetic testing to find out the cause of the disease?) remained statistically significant (β=2.457, SE=0.466, Wald c 2 =27.757, OR=11.671, 95%CI=4.679-29.115, P<0.001). Conclusions and discussion Increased SCD mortality rate and overlooked genetic causes The sudden death of young individuals evokes profound sorrow. For instance, just days before writing this article, a 17-year-old Chinese badminton player tragically died from SCA during a match in Indonesia [35]. News coverage focused on emergency response measures, neglecting potential underlying causes, such as structural heart abnormalities or ion channel disorders. SCD in athletes, especially high-profile ones, garners significant attention. A 2020 study by Egger et al. reported that between 2014 and 2018, 617 individuals experienced cardiac arrests globally under the auspices of FIFA, with an average age of 34 years [36]. A partial summary of SCD among doctors in recent years, as reported in the news ( Supplement Table 8 ), There were a total of 27 cases, with an average age of only 36 years, yet none of them underwent autopsies or genetic testing; the lack of emphasis on SCD genetic testing within the healthcare system has led to insufficient public awareness of the genetic causes of SCD, contributing to tragic instances of multiple family members experiencing SCD. This is another topic that we will analyze in detail in a separate article. Advancements in NGS now allow many SCD cases to be attributed to identifiable pathogenic causes through molecular pathology. Once diagnosed, these conditions can be effectively managed and prevented, supported by numerous expert consensus guidelines. For example, in long QT syndrome, using beta-blockers before age 40 can significantly reduce cardiovascular event risks [37]. If beta-blockers are ineffective, considering an implantable cardioverter-defibrillator (ICD) is recommended [38]. These measures can effectively prevent SCD. In summary, most genetically induced cases of SCD can be effectively prevented with proper diagnosis and management. The inadequacy of the emergency center's information system and the public's low compliance with pre-hospital emergency physicians led to a low recall rate for the project In our public welfare molecular epidemiology study on SCD in Hangzhou, we faced significant challenges in participant cooperation. Out of 199 cases, only four survivors or immediate family members agreed to participate. Several factors contributed to this low participation rate: 1. Inadequate information systems : The emergency center's information system is incomplete. Most emergency calls for SCD are made by family members, friends, or bystanders. Of the 199 phone numbers registered, 68 were invalid or went unanswered, and 69 were calls made by bystanders, resulting in a loss of contact with 137 cases. Improving the emergency center's information system to interface with the hospital inpatient system could enhance contact information, increasing the likelihood of follow-up and participation in studies. 2. Patients or their families often show low compliance with emergency center doctors , as these centers are responsible only for pre-hospital care, while hospitals manage subsequent treatment. For instance, among the 52 survivors or family members we contacted, 33 outright refused to participate. The most common reason for refusal was " I have already undergone a full examination at the hospital, and the doctor said my heart is healthy ." However, among the 18 individuals whose relatives had died, 14 expressed a willingness to cooperate with doctors in investigating SCD, despite not understanding its genetics. Similarly, among the 80 individuals who had a colleague or friend die, 40 were “ willing to cooperate with doctors or share the deceased’s lifestyle and work habits to analyze the causes of SCD ”. These data indicate that survivors or families and friends of the deceased show high compliance with hospital cardiologists. Therefore, future recommendations for genetic testing for SCD, whether free or paid, should be promoted through clinical doctors. Willingness to undergo genetic testing is significantly associated with the following factors Willingness to undergo genetic testing is significantly influenced by factors such as household income, health insurance coverage, education level, and religious beliefs, consistent with findings from various public surveys [21,22,26,28,39]. Individuals with higher income and education, those with health insurance, and those without religious affiliation tend to show greater willingness. Additionally, those with a family history of disease are more inclined to pursue genetic testing. For instance, surveys on Alzheimer's by Peter indicate that individuals with a family history of the disease exhibit the highest willingness for genetic testing.[27]. Similarly, Tiner's public survey shows that people with a cancer history or family history are more likely to accept genetic testing [40]—our results reflect this trend as well. Willingness rates are notably higher among those with personal connections to sudden cardiac death (SCD): 73.47% for individuals with a colleague, friend, or immediate family member affected, and 79.82% for those who have only seen reports in the news. In contrast, those without direct or indirect SCD experiences have a willingness rate of only 59.5% (Table 3). Interestingly, we found no significant differences in willingness based on prior genetic testing experiences. Follow-ups revealed that participants had undergone tests like MTHFR or NIPT but lacked a comprehensive understanding of these tests, having mostly signed informed consent forms prior (Table 3). Awareness of genetic diseases, such as deafness, ALS, and color blindness, correlates with a higher willingness for genetic testing (84% vs. 66%). This suggests that public education about genetic conditions can significantly enhance willingness to pursue testing. Gender differences also significantly affect willingness. Peter's research on Alzheimer's disease indicates that males are willing to pay more for genetic testing [27]. Conversely, another study shows that females are more receptive to genetic testing than males, and participants aged 40-65 are more inclined to undergo genetic testing compared to those aged 18-39[26]. Our data show that females are generally more willing than males (p=0.175, See Table 3). Age patterns differ as well: individuals over 50 exhibit the lowest willingness, followed by those aged 18-25, while the 35-50 age group shows the highest willingness. This discrepancy contrasts with other studies but aligns with China's socio-cultural context. This age group often faces a "midlife crisis," balancing the care of elderly parents and raising children—a situation intensified by the lasting effects of the "one-child policy." The stress of SCD in this demographic can lead to a greater openness toward genetic testing to mitigate future risks. Chinese public generally lack knowledge in medical genetics The genetic knowledge survey reveals that the general population in China has low levels of biomedical education. Even individuals with higher education but lacking biomedical backgrounds possess knowledge comparable to that of first-year senior middle school students. Among those unwilling to undergo genetic testing for sudden cardiac death (SCD), 50% believe SCD is unpreventable and that only avoiding activities like sports can mitigate risks, reflecting a critical misunderstanding of SCD risk management through genetic testing. To address this gap, Chinese universities should enhance their biomedical sciences offerings. Additionally, improving patient adherence to physicians' recommendations can be effective without overhauling the entire educational system. Physicians should receive training in basic medical genetics or genetic counseling through continuing education programs, enabling them to better educate patients about SCD and its genetic risks during consultations. Public awareness of SCD genetic testing can also be significantly improved through campaigns similar to the "Ice Bucket Challenge" or by leveraging media portrayals of SCD. Our survey indicates that some guiding questions and a brief educational segment convinced 47 individuals initially opposed to genetic testing to reconsider their stance. This perspective on public attitudes towards genetic testing for SCD is underrepresented in existing survey studies, highlighting a notable gap in the literature that our research seeks to address. The novelty of this study This study is the first in China, and possibly globally, to investigate public attitudes toward genetic testing for SCD. The research includes telephone follow-ups with 199 survivors or immediate family members of cardiac arrest victims and surveys of 536 members of the public regarding their attitudes toward SCD genetic testing. The novelty of this research lies in: Extensive Survey Coverage : This study includes not only the general public but also sudden cardiac arrest (SCA) survivors and immediate family members of SCA victims, unlike most surveys that focus solely on the public. Innovative Questionnaire Design : We incorporated a quality control mechanism in the questionnaire by repeating the same question at the beginning and end to filter out invalid responses. Educational Content Integration : The questionnaire included educational content and genetics questions to assess changes in public attitudes before and after exposure to scientific information. The results provide valuable insights for China’s medical genetics education system and public health outreach, highlighting the crucial role of primary care physicians in both treating and preventing cardiovascular diseases. This underscores the need for continuing education in genetic counseling for cardiovascular specialists. Limitations and Future Research Directions This study has several limitations. First, as the survey was conducted via mobile phones, participants may not have fully engaged with the educational content, similar to quickly agreeing to app terms and conditions, possibly affecting attitude changes. Future surveys should track response times to ensure meaningful engagement. Second, the lack of involvement from attending cardiology physicians contributed to survivors' refusal to participate. Engaging these clinicians could enhance compliance and willingness. A similar survey involving cardiologists and nurses in cardiovascular departments may yield deeper insights into medical professionals’ perspectives on genetic testing for SCD and identify educational needs. Lastly, the study was limited to Hangzhou in Zhejiang Province, potentially limiting the generalizability of findings due to regional and ethnic disparities in China. Future research should include a more diverse sample for broader applicability. Declarations Data AVAILABILITY All data is made available via supplementary materials Author Contributions Statement Xu-tao Hong was responsible for designing the questionnaire, writing and submitting the article. Xiao-ling Chen contributed to the telephone follow-up and questionnaire collection. Jian Huang, Shuang-yong Dong and Xiao-yan Xu contributed to recruiting respondents in the hospitals. Yan-bing He and Jin-yuan Wang contributed to extracting and analyzing data. Jian-gang Wang and Jun-geng Zhang collected and review the OHCA data. All the authors read and approved the final manuscript. Ming Qi and Jian-gang Wang provided the idea, and responsible for the whole study. Funding The study is supported by a grant from the Hangzhou Science and Technology Bureau (Project No. 20201203B187). Dian Diagnostic group, is an independent clinical laboratory (ICL). Ethical Approval Studies involving animal subjects Generated Statement: No animal studies are presented in this manuscript. Studies involving human subjects Generated Statement: The studies involving human participants were reviewed and approved by the Ethics Staff Hangzhou Emergency center (serial number: HZEMC-2020-09). Competing Interests The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. References Zhang S. Sudden cardiac death in China. Pacing Clin Electrophysiol. 2009; 32 : 1159-62. Zhang S. 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[Clinical practice guidelines for Long Q-T interval syndrome]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2020; 37 : 289-94. Borry P, Goffin T, Nys H, Dierickx K. Attitudes regarding predictive genetic testing in minors: a survey of European clinical geneticists. Am J Med Genet C Semin Med Genet. 2008; 148C : 78-83. Duncan RE, Savulescu J, Gillam L, Williamson R, Delatycki MB. An international survey of predictive genetic testing in children for adult onset conditions. Genet Med. 2005; 7 : 390-6. Mao X. Chinese geneticists' views of ethical issues in genetic testing and screening: evidence for eugenics in China. Am J Hum Genet. 1998; 63 : 688-95. Laskey SL, Williams J, Pierre-Louis J, O'Riordan M, Matthews A, Robin NH. Attitudes of African American premedical students toward genetic testing and screening. Genet Med. 2003; 5 : 49-54. Brunger JW, Murray GS, O'Riordan M, Matthews AL, Smith RJ, Robin NH. Parental attitudes toward genetic testing for pediatric deafness. 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Tables Table 1 Characteristics of the questionnaire (n=477 a ) Characteristics n Wgt % 1.Age, years 18-25 122 25.6 26-35 141 29.6 36-50 155 32.5 above 50 59 12.4 2.Sex female 194 40.7 male 283 59.3 3.Education level b High school or less 170 35.7 college or above 307 64.4 4.Career Housewives 89 18.7 IT practitioners 87 8.2 Drivers 72 15.1 Emergency volunteers 126 26.4 Cardiovascular patients' relatives 103 21.6 5.Income c 120k 137 34.8 keep secret 83 6.Medical_insurance No medicaid insurance 23 4.8 Rural Medical Insurance 96 20.1 Urban Medical Insurance 262 54.9 Medicaid plus commercial 96 20.1 7.Emergency volunteer certificate No 316 66.3 Yes 161 33.8 8.Religious beliefs d Yes 322 68.7 only believe in science 147 31.3 9.Have you ever heard of SCD Only seen in the news 337 70.7 I haven't had any incidents around me, nor have I followed any similar news 42 8.8 among colleagues or friends 80 16.8 among immediate family members 18 3.8 10.Genetic quiz score =7 192 40.3 11.Have you ever heard that deafness, amyotrophic lateral sclerosis (ALS), color blindness, hemophilia, and thalassemia are genetic diseases? No 136 28.5 Yes 341 71.5 12.Have received genetic testing before No 389 81.6 Yes 88 18.5 a After removing the invalid questionnaires b We combined the groups of <=9 year and <=12year c We will not conduct further statistical analysis on the 'keep secret' group d We categorized ‘a little’ and ‘keep secret’ in the ‘religion option’ as ‘having religious beliefs’ Table 2 Characteristics for the telephone follow-up Epidemiological features Total Survivors victims Patients n (%) 199 31 (15.5) 168 (84.5) Gender n (%) Male 141(71) 25 116 Female 58(29) 6 52 Age (Mean + IQR) 32.7±8.6 31.86±9.8 32.98±8.15 Location Home 64(32.2) 4 60 Public place 81(40.7) 18 63 Workplace 28(14) 6 22 unclear 26(13) 3 23 Who made the emergency call Immediate relatives 36(18.1) 6 30 Colleague, friends 26(13.1) 8 18 forward our SMS 18(9) 6 12 Reject our follow-up 8(4) 5 3 Passer-by or public staff 69(34.7) / / Missing (out of service, no answered) 68(34.2) / / Attitude towards telephone follow-ups (n=52) Willing to participate 19(36.5) 8 11 Completed genetic testing 4 3 1 Reject 33(63.5) 2 31 Table 3 Different characteristics on the willingness to undergo SCD genetic testing whether agree to genetic testing for SCD, n (%) c 2 P OR (95%CI) Agree (N=366) Disagree (N=111) age, years 8.455 0.015 18-25 97(26.5) 25(22.5) 0.550(0.313, 0.967) 26-35 96(26.2) 45(40.5) reference above 35 173(47.3) 41(36.9) 0.506(0.309, 0.826) sex 1.837 0.175 female 155(42.4) 39(35.1) reference male 211(57.7) 72(64.9) 1.356(0.872, 2.109) Education level 2.834 0.092 High school or less 123(33.6) 47(42.3) reference college or above 243(66.4) 64(57.7) 0.689(0.446, 1.064) Career Emergency volunteers 110(30.1) 16(14.4) 15.262 0.004 reference IT practitioners 61(16.7) 26(23.4) 2.930(1.460, 5.883) Housewives 65(17.8) 24(21.6) 2.538(1.257, 5.127) Drivers 48(13.1) 24(21.6) 3.437(1.677, 7.046) Cardiovascular patients' relatives 82(22.4) 21(18.9) 1.761(0.865, 3.583) income 3.583 0.167 120k 116(36.9) 21(26.3) 1.207(0.639, 2.282) keep secret 83 medical insurance 14.427 0.001 No Medicaid Insurance 13(3.6) 10(9.0) reference Rural Medical Insurance 62(16.9) 34(30.6) 0.713(0.283, 1.797) Urban Medical Insurance 212(57.9) 50(45.1) 0.307(0.127, 0.739) Medicaid plus commercial 79(21.6) 17(15.3) 0.280(0.105, 0.743) P for trend 0.047 Emergency volunteer certificate 0.631 0.427 No 239(65.3) 77(69.4) reference Yes 127(34.7) 34(30.6) 0.831(0.526, 1.313) Religious beliefs 11.64 0.001 Yes 98(27.3) 49(44.6) reference only believe in science 261(72.7) 61(55.5) 0.467(0.300, 0.727) Have you ever heard of SCD 9.371 0.025 Only seen in the news 269(73.5) 68(61.3) 0.372(0.190, 0.727) I haven't had any incidents around me, nor have I followed any similar news 25(6.8) 17(15.3) reference among colleagues or friends or immediate family members 72(19.7) 26(23.4) 0.531(0.248, 1.138) genetic score 0.263 0.608 =7 145(39.6) 47(42.3) 1.119(0.727, 1.722) Have you received genetic testing before 3.275 0.07 No 292(79.8) 97(87.4) reference Yes 74(20.2) 14(12.6) 0.570(0.308, 1.054) Table 4 Attitude change after science education Change to agree, n (%) c 2 P OR (95%CI) Disagree (N=64) Agree (N=47) Age, years 2.923 0.404 18-25 17(26.6) 8(17.0) reference 26-35 22(34.4) 23(48.9) 2.221(0.798, 6.183) 36-50 17(26.6) 12(25.5) 1.500(0.490, 4.592) above 50 8(12.5) 4(8.5) 1.062(0.245, 4.599) Age, years 2.698 0.26 18-25 17(26.6) 8(17.0) 0.450(0.162, 1.253) 26-35 22(34.4) 23(48.9) reference Above 35 25(39.1) 16(34.0) 0.612(0.260, 1.443) Sex 3.259 0.071 Female 18(28.1) 21(44.9) reference Male 46(71.9) 26(55.3) 0.484(0.219, 1.070) Education level 0.666 0.414 High school or less 25(39.1) 22(46.8) reference College or above 39(60.9) 25(53.2) 0.728(0.340, 1.560) Career 5.932 0.204 Housewives 11(17.2) 5(10.6) reference IT practitioners 16(25.0) 10(21.3) 1.375(0.367, 5.145) Drivers 11(17.2) 13(27.7) 2.600(0.689, 9.805) Emergency volunteers 17(26.6) 7(14.9) 0.906(0.229, 3.585) Cardiovascular patients' relatives 9(14.1) 12(25.5) 2.933(0.749, 11.490) Income* 0.288 0.866 120k 11(26.2) 10(26.3) 0.808(0.225, 2.909) Medical insurance 3.355 0.34 No Medicaid insurance 7(10.9) 3(6.4) reference Rural Medical Insurance 16(25.0) 18(38.3) 2.624(0.579, 11.890) Urban Medical Insurance 29(45.3) 21(44.7) 1.689(0.391, 7.306) Medicaid plus commercial 12(18.8) 5(10.6) 0.972(0.176, 5.365) A1 Emergency volunteer certificate 0.997 0.318 No 42(65.6) 35(74.5) reference Yes 22(34.4) 12(25.5) 0.655(0.284, 1.507) A2 Religious beliefs * 0.952 0.329 Yes 26(40.6) 23(50.0) reference Only believe in science 38(59.4) 23(50.0) 0.684(0.319, 1.468) A3 Have you ever heard of SCD 0.258 0.879 Only seen in the news 10(15.6) 7(14.9) reference I haven't had any incidents around me, nor have I followed any similar news 38(59.4) 30(63.8) 1.128(0.384, 3.314) Among colleagues or friends 16(26.0) 10(21.3) 0.893(0.256, 3.110) Genetic quiz score 0.123 0.726 =7 28(43.8) 19(40.4) 0.872(0.406, 1.873) (AE) Have you ever heard that deafness, amyotrophic lateral sclerosis (ALS), color blindness, hemophilia, and thalassemia are genetic diseases? 0.26 0.61 No 22(34.4) 14(29.8) reference Yes 42(65.6) 33(70.2) 1.235(0.549, 2.777) (AF) Do you think these deaf, ALS, colorblind, and hemophilia patients should undergo genetic testing to find out the cause of the disease? 31.95 <0.001 No 47(73.4) 9(19.2) reference Yes 17(26.6) 38(80.9) 11.671(4.679, 29.115) (AG) Do you think relatives of people with deafness, ALS, color blindness, and hemophilia should do genetic testing before giving birth to the next generation to avoid giving birth to fetuses with similar conditions? 19.281 <0.001 No 39(60.9) 9(19.2) reference Yes 25(39.1) 38(80.9) 6.586(2.723, 15.930) (AH) Many of the SCD of young people are also related to genetics, and the immediate relatives also have a certain probability of carrying the risk of sudden death 13.789 <0.001 Do not believe 47(73.4) 18(38.3) reference Believe 17(26.6) 29(61.7) 4.454(1.985, 9.997) (AI) Have you receive genetic testing before 3.16 0.076 No 59(92.2) 38(80.9) referrence Yes 5(7.8) 9(19.2) 2.795(0.870, 8.975) * Missing data were not included in the analysis Additional Declarations (Not answered) Supplementary Files SupplementalTable1.xlsx SupplementalTable2.xlsx SupplementalTable3.xlsx SupplementalTable4.xlsx SupplementalTable5.xlsx SupplementalTable6.xlsx SupplementalTable7.xlsx SupplementalTable8.xlsx Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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03:30:56","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-5257725/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-5257725/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":67634295,"identity":"9e1af196-26e3-43b3-a1dd-d59c7b7e52ea","added_by":"auto","created_at":"2024-10-28 09:15:28","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":152786,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eAttitudes of different types of personnel towards genetic testing, whether they have undergone genetic testing, and their genetic scores\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFigure 1A presents a bar graph illustrating the attitudes toward genetic testing among different career groups, with the x-axis representing various types of individuals and the y-axis indicating the proportion of responses classified as \"Agree\" or 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This also contributes to the high mortality rate of cardiovascular diseases. The incidence varies across different regions or countries. The incidence of cardiovascular diseases in China was 41.8 per 100,000 individuals in 2005[\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e, \u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e], doubling to 95.7 per 100,000 by 2020[\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e]. In comparison, Europe and the U.S. report a prevalence ranging between 50 and 100 cases per 100,000 individuals [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e]. Among these diseases, coronary artery disease is most prevalent, leading to a rise in SCD, a substantial healthcare burden in China. Despite ongoing efforts like distributing automatic external defibrillators (AEDs) in public places, few policies and preventative measures have been implemented. According to studies, SCD accounts for over 750,707 deaths annually among China's citizens [\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eCoronary heart disease is a common cause of sudden cardiac death (SCD) in the elderly, while genetic factors are often responsible in younger individuals, particularly those with a family history of SCD. Advances in next-generation sequencing (NGS) have identified genes related to arrhythmias and cardiomyopathies, uncovering causes of previously unexplained SCD cases [\u003cspan additionalcitationids=\"CR7\" citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e]. In young individuals, SCD is often linked to genetic causes, with conditions such as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), myocarditis, and various arrhythmogenic disorders like Brugada syndrome (BrS) and long-QT syndrome (LQTS)[\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e]. These genetic disorders, typically autosomal dominant, mean immediate relatives have a 50% risk of inheriting the pathogenic variant [\u003cspan citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e]. Therefore, genetic testing is crucial for survivors and their families, aiding in clarifying the SCD etiology, offering personalized medical treatments, and evaluating preventive strategies like the effectiveness of implantable defibrillators [\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eGuidelines from global bodies such as the American Heart Association and the European Society of Cardiology highlight the importance of genetic testing for inherited cardiovascular diseases [\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e], and the 2015 European society of cardiology (ESC) guidelines show the value of genetic screening for family members of SCD victims[\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e]. Similarly, expert consensus in China recommends genetic testing as per the Long-QT Syndrome and Hereditary Cardiomyopathy Clinical Practice Guidelines [\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eTo investigate the molecular epidemiology of SCA in Hangzhou, The Hangzhou Emergency Center of Zhejiang Province launched a charity project from 2020 to 2022 to provide free genetic testing for individuals under 50 who experienced sudden unexplained deaths. However, a significant number of survivors and victims' immediate relatives expressed concerns or even opposition to genetic testing. This study aims to investigate the attitudes of SCD survivors, victims' relatives, and the public towards genetic testing through a comprehensive survey.\u003c/p\u003e \u003cp\u003eThere have been many genetic testing surveys since the completion of Human Genome Project, but initially, they were generally for geneticists or doctors [\u003cspan additionalcitationids=\"CR17\" citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e], and some public surveys were for the special diseases, such as deafness [\u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e, \u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e]. The advent of NGS has reduced the cost of whole exome sequencing, promoting its clinical use, and surveys have been conducted globally [\u003cspan additionalcitationids=\"CR22\" citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e], focusing mostly on reproductive health and supporting prenatal genetic testing to avoid birth defects. Few surveys have focused on cardiovascular issues, mainly conducted by direct-to-consumer health and insurance companies, and none specifically targeted SCD survivors or their families. Moreover, no questionnaire survey targeting SCD survivors or victims\u0026rsquo; immediate family members. Survey methodology has evolved from traditional paper-and-pencil forms to email and, more recently, to popular mobile-based formats [\u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e, \u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eThis study\u0026rsquo;s objectives are to explore the public's attitudes towards SCD genetic testing and to identify significant differences based on demographic factors. It will also investigate the concerns of individuals with negative attitudes and assess whether information dissemination can influence their choices.\u003c/p\u003e"},{"header":"Materials and Methods","content":"\u003cp\u003e\u003cstrong\u003eStudy design for\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;telephone follow-up\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe conducted a retrospective study on 9585 OHCA\u0026nbsp;cases of Hangzhou Emergency Center, between January 2015 and December 2021. We focused on the cases for telephone follow-up, the principles are as following: i). Under the age of 50. ii). Cardiac arrest, especially ventricular fibrillation. iii). Exclude clear causes, such as: car accident, suicide, homicide, coronary heart disease, cerebral infarction etc.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTelephone follow-up\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe prepared two scripts for the telephone follow-up (See\u003cstrong\u003e\u0026nbsp;Supplemental Table 1\u003c/strong\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStudy design for questionnaire survey\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA likert-scale written questionnaire was developed to gauge the public\u0026rsquo;s views on various topics related to the genetics [22,25-29], including knowledge of genetics and gene testing [30]; preferences among potential providers of gene testing; preferences among potential providers of SCD gene testing; and future expectations and concerns regarding SCD gene testing. This study was approved by the Ethics Committee of the Hangzhou Emergency Center.\u003c/p\u003e\n\u003cp\u003eWe adopted the currently popular mobile-based survey method by designing a website for the questionnaire [24,31], A QR code was generated to enable respondents to easily scan and complete the survey on their cell phones.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eParticipants\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eConvenience sampling was used to select participants, grouped as follows:\u003c/p\u003e\n\u003cp\u003ei. \u003cstrong\u003eFirst Aid Trainees:\u003c/strong\u003e Participants from the Hangzhou Emergency Center\u0026apos;s primary first aid training class, representing various societal sectors but all trained in SCD concepts and CPR. ii. \u003cstrong\u003eGeneral Population:\u003c/strong\u003e Employees from nearby office buildings and housewives shopping, serving as the control group. iii. \u003cstrong\u003eIT practitioners:\u003c/strong\u003e Employees from Alibaba Group and similar companies in Hangzhou, characterized by young age, high salaries, intense work schedules (\u0026apos;996\u0026apos;), with frequent SCD cases. iv. \u003cstrong\u003eRelatives of Cardiovascular Patients:\u003c/strong\u003e Immediate family or caregivers of ICU and cardiovascular ward patients, likely decision-makers for future genetic testing for SCD. v. \u003cstrong\u003eRide-Hailing Drivers:\u003c/strong\u003e Taxi and online car-hailing drivers, a high-risk group for SCD due to poor working conditions and irregular lifestyles.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEligibility Criteria:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ei). Aged 18 years or older\u003c/p\u003e\n\u003cp\u003eii). Ability to understand, speak Mandarin, and read Chinese.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Control:\u003c/strong\u003e To ensure the quality of responses, a multiple-choice question about the respondent\u0026apos;s age was included at both the beginning and end of the questionnaire. Inconsistent answers classified the questionnaire as invalid.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuestionnaire contents\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe questionnaire consists of five parts:\u003c/p\u003e\n\u003cp\u003e1.Demographic Attributes: Nine questions on gender, age, weekly working hours, education level, occupations, annual income, medical insurance coverage, CPR training participation, and religious beliefs.\u0026nbsp;[17,22,32,33].\u003c/p\u003e\n\u003cp\u003e2. Attitudes Towards SCD: Four questions on:\u003c/p\u003e\n\u003col\u003e\n \u003cli\u003eAwareness of SCD\u003c/li\u003e\n \u003cli\u003eResponse to professional consultation about SCD\u003c/li\u003e\n \u003cli\u003eAttitude towards genetic testing for SCD in family/friends if recommended by a doctor\u003c/li\u003e\n \u003cli\u003eReasons for agreement, neutrality, or disagreement with genetic testing [34].\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003e3. Genetic Knowledge: Ten questions to assess respondents\u0026apos; genetic knowledge [30].\u003c/p\u003e\n\u003cp\u003e4. Importance of Genetic Testing: Highlights known genetic conditions (e.g., hereditary deafness, ALS, thalassemia), includes brief educational segments on genetic aspects related to SCA.\u003c/p\u003e\n\u003cp\u003e5. Attitudes Post-Education: Repeats questions on attitudes towards genetic testing for SCD to gauge changes after exposure to educational content.\u003c/p\u003e\n\u003cp\u003eThe questionnaire draws from existing surveys while incorporating innovative designs such as educational passages on the genetic basis of SCD and a before-and-after approach to assess attitude changes. The counts for each of these groups are reported separately in \u003cstrong\u003eTable 1\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eData analyses\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eOnce the respondents finish the questionnaire survey, we can export all the data from the website. p-Values of 0.05 and 0.01 were used for distinguishing between different levels of statistical significance.\u003c/p\u003e\n\u003cp\u003eStatistical analysis of the study was performed using SAS version 9.4 (SAS Institute Inc., Cary, NC, USA). Data are presented as numbers and percentages and analyzed by chi-square test. An unconditional logistic regression model was used to calculate the odds ratio (OR) and 95% confidence intervals (CI) for the risk factors of choice of gene test in a manner of univariate or multivariate with stepwise selection. A two-sided P \u0026lt; 0.05 was considered statistically significant.\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cstrong\u003eTelephone follow-up results\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFrom 199 enrolled cases, the median age was 32\u0026plusmn;8.6 years, with 141 (71%) men. SCD incidents occurred at home (64 cases, 32.2%), workplaces (28 cases, 14%), and public places like subways and hotels (81 cases, 40.7%). There are 31(15.8%) survivors (labeled as \u0026apos;Survivors\u0026apos;) while and 168 (84.4%) victims (labeled as \u0026apos;Victims\u0026apos;) (\u003cstrong\u003eTable 2\u003c/strong\u003e).\u003c/p\u003e\n\u003cp\u003eEmergency calls: 36 (18%) made by immediate relatives, 26 by colleagues/friends (18 provided contact info). Among 69 public emergency calls, most callers either couldn\u0026rsquo;t recall the event or lacked contact information. Additionally, 68 calls were out of service or invalid.\u003c/p\u003e\n\u003cp\u003eWe contacted 10 survivors and 42 victims\u0026apos; relatives. Of the survivors, 8 were willing to participate, but only 3 completed genetic testing. For the victim\u0026apos;s relatives, 11 were initially willing but only 1 participated in genetic testing. The rest declined for various reasons or did not provide a reason.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eReasons for declining SCD genetic testing\u003c/strong\u003e\u003c/p\u003e\n\u003col\u003e\n \u003cli\u003e\u003cstrong\u003eSurvivor:\u003c/strong\u003e\u003c/li\u003e\n\u003c/ol\u003e\n\u003col start=\"1\" type=\"i\"\u003e\n \u003cli\u003e\u0026quot;\u003cem\u003eI have undergone a comprehensive heart ultrasound and other diagnostic tests. The doctor concluded that my heart is healthy. and my cardiac arrest was attributed to extreme fatigue\u003c/em\u003e.\u0026quot;\u003c/li\u003e\n \u003cli\u003e\u0026quot;\u003cem\u003eNothing like this has happened in my family; my cardiac arrest definitely had nothing to do with genetics\u003c/em\u003e.\u0026quot;\u003c/li\u003e\n\u003c/ol\u003e\n\u003col start=\"2\"\u003e\n \u003cli\u003e\u003cstrong\u003eVictim\u0026rsquo;s Spouse (No Children):\u003c/strong\u003e \u0026quot;\u003cem\u003eHe/She is my ex-boyfriend/ex-girlfriend, and I currently have no contact with his/her family. I hope to move on from this matter as soon as possible\u003c/em\u003e.\u0026quot;\u003c/li\u003e\n \u003cli\u003e\u003cstrong\u003eVictim\u0026rsquo;s Parents:\u003c/strong\u003e \u0026quot; \u003cem\u003eOur family has no history of similar situations. Both my spouse and I are in good health, so it\u0026apos;s unlikely this is caused by genetic factors. There\u0026apos;s no need for testing.\u003c/em\u003e\u0026quot;\u003c/li\u003e\n \u003cli\u003e\u003cstrong\u003eVictim\u0026rsquo;s Siblings:\u003c/strong\u003e \u0026quot;\u003cem\u003eThere\u0026apos;s no history of such conditions in our family. Our parents are also healthy, so it\u0026apos;s unlikely this is genetic. Testing is unnecessary.\u003c/em\u003e\u0026quot;\u003c/li\u003e\n \u003cli\u003e\u003cstrong\u003eVictim\u0026rsquo;s Spouse (With Kids):\u003c/strong\u003e \u0026quot;\u003cem\u003eMy child is currently very healthy, and we don\u0026apos;t believe genetics play a role. We don\u0026apos;t wish to undergo testing\u003c/em\u003e.\u0026quot;\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003e\u003cstrong\u003eLager scale public survey of knowledge and attitudes regarding SCD genetic testing\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAfter removing the invalid questionnaires, we received a total of 477 valid responses (The original survey data is presented in \u003cstrong\u003eSupplemental Table 2\u003c/strong\u003e). We use \u0026apos;Willingness to undergo SCD genetic testing\u0026apos; (column P) as the independent variable (Responses of \u0026quot;agree\u0026quot; and \u0026quot;strongly agree\u0026quot; were categorized as \u0026ldquo;yes\u0026rdquo;=0, while all other responses were categorized as \u0026ldquo;no\u0026rdquo;=1). We perform univariate logistic regression analysis with other indicators as independent variables. Categorical variables are entered into the model as dummy variables. A total of 366 participants agreed to undergo SCD genetic testing, while 111 participants disagreed (\u003cstrong\u003eTable 3\u003c/strong\u003e)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eParticipants\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe results in \u003cstrong\u003eTable 3\u003c/strong\u003e and \u003cstrong\u003eSupplemental Table 3\u003c/strong\u003e reflect current trends in China. In the \u0026apos;Gender\u0026apos; category, the IT practitioners show an almost equal male-female distribution, while drivers are predominantly male (95.8%). Emergency volunteers are mostly male (63.5% vs. 36.5%). Men are less willing to undergo SCD genetic testing (OR=1.356, 95% CI=0.876-2.122, p=0.176).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eOccupations\u003c/strong\u003e Different occupations show significant differences in willingness for SCD genetic testing: emergency volunteers are the most willing, followed by cardiovascular patients\u0026rsquo; relatives, with drivers, IT practitioners, and housewives showing less interest (p=0.004).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAge\u003c/strong\u003e In the IT practitioners, 95.4% of employees are under 35 years old, aligning with the \u0026apos;35-year unemployment line.\u0026apos; Educational attainment is high, with 97.7% of IT workers and 86.5% of emergency volunteers having higher education. The \u0026apos;35-50 years\u0026apos; group is most willing to undergo testing, while the \u0026apos;25-35 years\u0026apos; group is less willing (OR=0.550, 95% CI=0.313-0.967). Combining ages 36 and older: OR=0.506, 95% CI=0.309-0.826, p=0.015.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eIncome\u003c/strong\u003e An annual income exceeding 120k yuan was classified as high. Among different occupations, drivers had the lowest proportion in this category (15.3%), while emergency volunteers had the highest (44.4%). Regarding working hours, 12.7% of drivers reported working over 70 hours per week. The distribution of drivers working 40-50 hours, 50-60 hours, and 60-70 hours per week was 23.6%, 5.45%, and 12.73%, respectively. Notably, only 45.45% of drivers worked fewer than 40 hours per week (\u003cstrong\u003eSupplemental Table 3\u003c/strong\u003e). We did not adjust income based on working hours, and high-income groups showed no significant difference in willingness to undergo SCD genetic testing (p = 0.167).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eHealth Insurance\u003c/strong\u003e Most respondents have medical insurance. However, 9.2% of IT workers and 12.5% of drivers do not. Additional commercial insurance is more common among emergency volunteers (27.8%). Willingness for testing increases with better insurance coverage (p-trend \u0026lt;0.001).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eReligious Beliefs\u003c/strong\u003e Out of 477 respondents, 322 believe in science, while 12 are devout believers, 43 individuals chose \u0026apos;keep secret,\u0026apos; others selected \u0026apos;a little bit.\u0026apos; We included those \u0026lsquo;keep secret\u0026apos; in the \u0026apos;religious beliefs\u0026apos; category for statistical analysis. 33.3% of individuals with \u0026apos;religious beliefs\u0026apos; chose to refuse, whereas only 18.9% of those who \u0026apos;trust science\u0026apos; opted to refuse, indicating that individuals who trust science are more willing to undergo SCD genetic testing (OR=0.467, 95% CI=0.3-0.727, p \u0026lt;0.001).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAwareness of SCD\u003c/strong\u003e\u003c/p\u003e\n\u003cul type=\"disc\"\u003e\n \u003cli\u003e337 respondents have only seen SCD in the news.\u003c/li\u003e\n\u003c/ul\u003e\n\u003cul\u003e\n \u003cli\u003e18 have experienced it among family members, with 8 from the \u0026apos;emergency volunteer\u0026apos; group strongly supporting genetic testing. Additionally, 5 respondents stated they were \u0026apos;uncertain but willing to cooperate with doctors.\u0026apos;\u003c/li\u003e\n\u003c/ul\u003e\n\u003cul type=\"disc\"\u003e\n \u003cli\u003e80 have witnessed SCD among colleagues or friends; 40 are willing to cooperate with doctors.\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWillingness for Genetic Testing\u003c/strong\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e366 respondents are willing to undergo genetic testing, highest among emergency volunteers (87.3%) and lowest among drivers (66.7%). Significant differences exist among groups, with the strongest willingness shown by those who \u0026apos;only saw it in the news\u0026apos; (OR=0.372, 95% CI=0.19-0.727). When combining those with personal experiences related to SCD, the odds ratio is OR=0.531, 95% CI=0.248-1.138, p=0.025.\u003c/p\u003e\n\u003cp\u003eParticipant knowledge was assessed through 10 questions (\u003cstrong\u003eSupplemental Table 4\u003c/strong\u003e), with correct response rates ranging from 54.2% to 66.2%. Nine questions were true/false, and one was multiple-choice.\u003c/p\u003e\n\u003cp\u003eInfluenced by traditional Chinese \u0026apos;patrilineal society\u0026apos; and similar ideologies, such as those in the question \u0026apos;People share more genes with their paternal cousins than their maternal cousins,\u0026apos; \u0026mdash;over 60% of \u0026apos;housewives\u0026apos; incorrectly responded \u0026quot;True.\u0026quot; \u0026nbsp;Furthermore, even among IT practitioners and emergency volunteers, the correct response rates were only 72.8% and 59.5%, respectively, indicating that higher education in China often overlooks medical genetics.\u003c/p\u003e\n\u003cp\u003eFor instance, the question \u0026quot;Every trait is controlled by a specific single gene\u0026quot; had the lowest correct response rates, ranging from 24% to 47%. Common misconceptions regarding \u0026apos;genetic diseases\u0026apos; requiring a family history were also prevalent.\u003c/p\u003e\n\u003cp\u003eScores \u0026le;6 were considered low, and \u0026ge;7 high. No significant differences were found between these groups (p=0.608,\u003cstrong\u003e\u0026nbsp;See Table 3\u003c/strong\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eComparative willingness for SCD testing among different occupations Groups\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe study conducted a comparative analysis of the willingness to undergo genetic testing, the actual participation in genetic testing, and the statistical evaluation of genetic assessment across five different occupations groups. The results indicate that emergency volunteers exhibited significantly higher levels in all aspects compared to other groups, including a greater willingness to undergo genetic testing (Emergency volunteers VS Non-Emergency volunteers, p=0.00419), a higher number of volunteers who have undergone genetic testing (p=0.002583), and elevated scores in genetic assessments (See \u003cstrong\u003eFigure 1\u003c/strong\u003e, \u003cstrong\u003eSupplementary Tables 5 and 6\u003c/strong\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eReasons for supporting SCD genetic testing (n= 337)\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e1. \u0026ldquo;\u003cem\u003eEarly intervention and treatment for the high-risk members\u0026rdquo;\u003c/em\u003e. 247 (73.2%)\u003c/p\u003e\n\u003cp\u003e2. \u0026ldquo;\u003cem\u003eCan help to identify the cause of SCD\u0026rdquo;.\u0026nbsp;\u003c/em\u003e230 (68.2%)\u003c/p\u003e\n\u003cp\u003e3. \u0026ldquo;\u003cem\u003eInformed family planning to prevent the next child carrying the pathogenic mutation\u0026rdquo;.\u0026nbsp;\u003c/em\u003e228 (67.7%)\u003c/p\u003e\n\u003cp\u003e4.\u003cem\u003e\u0026nbsp;\u0026ldquo;I willing to support the SCD genetic research\u0026rdquo;.\u0026nbsp;\u003c/em\u003e201 (59.6%)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eReasons for un-supporting SCD genetic testing (n=26)\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e1. \u0026ldquo;\u003cem\u003eIf I tested high risk, can\u0026rsquo;t climb mountains, can\u0026apos;t play ball, can\u0026apos;t do strenuous exercise, if only in this way can prevent sudden death, what is the meaning of life like this\u0026rdquo;.\u003c/em\u003e 13 (50%)\u003c/p\u003e\n\u003cp\u003e2. \u003cem\u003e\u0026ldquo;I am health now, and I don\u0026rsquo;t want to know my SCD risk\u0026rdquo;, \u0026ldquo;Knowing a result that cannot be changed is worse than not knowing\u0026rdquo;.\u003c/em\u003e 9 (34.6%)\u003c/p\u003e\n\u003cp\u003e3. \u0026ldquo;\u003cem\u003eThe genetic testing will cause stress to my kids\u0026rdquo;.\u003c/em\u003e 7 (26.9%)\u003c/p\u003e\n\u003cp\u003e4. \u003cem\u003e\u0026ldquo;If I tested high risk, it would cause trouble for my insurance\u0026rdquo;, \u0026ldquo;I / My kids will be discriminated by others in case of the positive test results\u0026rdquo;.\u003c/em\u003e 4 (15.4%)\u003c/p\u003e\n\u003cp\u003e5. \u003cem\u003e\u0026ldquo;I don\u0026rsquo;t think the SCD is genetically related\u0026rdquo;, \u0026ldquo;I think SCD is scientifically unclear\u0026rdquo;\u003c/em\u003e. 2 (7.7%)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMultivariate analysis\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eConsidering the relatively small sample size of this study, we reorganized the significant indicators from Table 2 for multivariate analysis. Age was categorized into two groups: under 35 and 35 and over. Occupation was divided into emergency volunteers and other categories. Insurance status was classified as uninsured and insured. The K variable was categorized into those who had not experienced or paid attention to similar news and those who had seen or heard about it. Using the willingness to undergo genetic testing as the dependent variable (yes=0, no=1), we employed stepwise selection to construct a logistic regression model with these indicators as independent variables. The statistically significant indicators identified were Occupations, Religious beliefs (\u003cstrong\u003eSupplemental Table 7\u003c/strong\u003e)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAttitude change after science education\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAmong the 477 participants in the survey, 111 initially disagreed with genetic testing. After three guided multiple-choice questions and a segment of educational content on the subject, 47 of these individuals changed their stance to agree (\u003cstrong\u003eTable 4\u003c/strong\u003e). Using whether the participant changed to agree with genetic testing as the dependent variable (yes=1, no=0), logistic regression analysis was performed with the following indicators as independent variables.\u003c/p\u003e\n\u003cp\u003eAll statistically significant indicators were included in the model, and stepwise logistic regression analysis was conducted. Ultimately, only column AF (Do you think these deaf, ALS, colorblind, and hemophilia patients should undergo genetic testing to find out the cause of the disease?) remained statistically significant (\u0026beta;=2.457, SE=0.466, Wald\u0026nbsp;c\u003csup\u003e2\u003c/sup\u003e=27.757, OR=11.671, 95%CI=4.679-29.115, P\u0026lt;0.001).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusions and discussion\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eIncreased SCD mortality rate and overlooked genetic causes\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe sudden death of young individuals evokes profound sorrow. For instance, just days before writing this article, a 17-year-old Chinese badminton player tragically died from SCA during a match in Indonesia [35]. News coverage focused on emergency response measures, neglecting potential underlying causes, such as structural heart abnormalities or ion channel disorders. SCD in athletes, especially high-profile ones, garners significant attention. A 2020 study by Egger et al. reported that between 2014 and 2018, 617 individuals experienced cardiac arrests globally under the auspices of FIFA, with an average age of 34 years [36]. A partial summary of SCD among doctors in recent years, as reported in the news (\u003cstrong\u003eSupplement Table 8\u003c/strong\u003e), There were a total of 27 cases, with an average age of only 36 years, yet none of them underwent autopsies or genetic testing; the lack of emphasis on SCD genetic testing within the healthcare system has led to insufficient public awareness of the genetic causes of SCD, contributing to tragic instances of multiple family members experiencing SCD. This is another topic that we will analyze in detail in a separate article.\u003c/p\u003e\n\u003cp\u003eAdvancements in NGS now allow many SCD cases to be attributed to identifiable pathogenic causes through molecular pathology. Once diagnosed, these conditions can be effectively managed and prevented, supported by numerous expert consensus guidelines. For example, in long QT syndrome, using beta-blockers before age 40 can significantly reduce cardiovascular event risks [37]. If beta-blockers are ineffective, considering an implantable cardioverter-defibrillator (ICD) is recommended [38]. These measures can effectively prevent SCD.\u0026nbsp;In summary, most genetically induced cases of SCD can be effectively prevented with proper diagnosis and management.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe inadequacy of the emergency center\u0026apos;s information system and the public\u0026apos;s low compliance with pre-hospital emergency physicians led to a low recall rate for the project\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIn our public welfare molecular epidemiology study on SCD in Hangzhou, we faced significant challenges in participant cooperation. Out of 199 cases, only four survivors or immediate family members agreed to participate. Several factors contributed to this low participation rate:\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e1. Inadequate information systems\u003c/strong\u003e: The emergency center\u0026apos;s information system is incomplete. Most emergency calls for SCD are made by family members, friends, or bystanders. Of the 199 phone numbers registered, 68 were invalid or went unanswered, and 69 were calls made by bystanders, resulting in a loss of contact with 137 cases. Improving the emergency center\u0026apos;s information system to interface with the hospital inpatient system could enhance contact information, increasing the likelihood of follow-up and participation in studies.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2. Patients or their families often show low compliance with emergency center doctors\u003c/strong\u003e, as these centers are responsible only for pre-hospital care, while hospitals manage subsequent treatment. For instance, among the 52 survivors or family members we contacted, 33 outright refused to participate. The most common reason for refusal was \u0026quot;\u003cem\u003eI have already undergone a full examination at the hospital, and the doctor said my heart is healthy\u003c/em\u003e.\u0026quot;\u003c/p\u003e\n\u003cp\u003eHowever, among the 18 individuals whose relatives had died, 14 expressed a willingness to cooperate with doctors in investigating SCD, despite not understanding its genetics. Similarly, among the 80 individuals who had a colleague or friend die, 40 were \u0026ldquo;\u003cem\u003ewilling to cooperate with doctors or share the deceased\u0026rsquo;s lifestyle and work habits to analyze the causes of SCD\u003c/em\u003e\u0026rdquo;.\u003c/p\u003e\n\u003cp\u003eThese data indicate that survivors or families and friends of the deceased show high compliance with hospital cardiologists. Therefore, future recommendations for genetic testing for SCD, whether free or paid, should be promoted through clinical doctors.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eWillingness to undergo genetic testing is significantly associated with the following factors\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWillingness to undergo genetic testing is significantly influenced by factors such as household income, health insurance coverage, education level, and religious beliefs, consistent with findings from various public surveys [21,22,26,28,39]. Individuals with higher income and education, those with health insurance, and those without religious affiliation tend to show greater willingness. \u0026nbsp;Additionally, those with a family history of disease are more inclined to pursue genetic testing. For instance, surveys on Alzheimer\u0026apos;s by Peter indicate that individuals with a family history of the disease exhibit the highest willingness for genetic testing.[27]. Similarly, Tiner\u0026apos;s public survey shows that people with a cancer history or family history are more likely to accept genetic testing [40]\u0026mdash;our results reflect this trend as well. Willingness rates are notably higher among those with personal connections to sudden cardiac death (SCD): 73.47% for individuals with a colleague, friend, or immediate family member affected, and 79.82% for those who have only seen reports in the news. In contrast, those without direct or indirect SCD experiences have a willingness rate of only 59.5% (Table 3). Interestingly, we found no significant differences in willingness based on prior genetic testing experiences. Follow-ups revealed that participants had undergone tests like MTHFR or NIPT but lacked a comprehensive understanding of these tests, having mostly signed informed consent forms prior (Table 3).\u003c/p\u003e\n\u003cp\u003eAwareness of genetic diseases, such as deafness, ALS, and color blindness, correlates with a higher willingness for genetic testing (84% vs. 66%). This suggests that public education about genetic conditions can significantly enhance willingness to pursue testing.\u003c/p\u003e\n\u003cp\u003eGender differences also significantly affect willingness. Peter\u0026apos;s research on Alzheimer\u0026apos;s disease indicates that males are willing to pay more for genetic testing [27]. Conversely, another study shows that females are more receptive to genetic testing than males, and participants aged 40-65 are more inclined to undergo genetic testing compared to those aged 18-39[26]. Our data show that females are generally more willing than males (p=0.175, See Table 3). Age patterns differ as well: individuals over 50 exhibit the lowest willingness, followed by those aged 18-25, while the 35-50 age group shows the highest willingness. This discrepancy contrasts with other studies but aligns with China\u0026apos;s socio-cultural context. This age group often faces a \u0026quot;midlife crisis,\u0026quot; balancing the care of elderly parents and raising children\u0026mdash;a situation intensified by the lasting effects of the \u0026quot;one-child policy.\u0026quot; The stress of SCD in this demographic can lead to a greater openness toward genetic testing to mitigate future risks.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eChinese public generally lack knowledge in medical genetics\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe genetic knowledge survey reveals that the general population in China has low levels of biomedical education. Even individuals with higher education but lacking biomedical backgrounds possess knowledge comparable to that of first-year senior middle school students. Among those unwilling to undergo genetic testing for sudden cardiac death (SCD), 50% believe SCD is unpreventable and that only avoiding activities like sports can mitigate risks, reflecting a critical misunderstanding of SCD risk management through genetic testing.\u003c/p\u003e\n\u003cp\u003eTo address this gap, Chinese universities should enhance their biomedical sciences offerings. Additionally, improving patient adherence to physicians\u0026apos; recommendations can be effective without overhauling the entire educational system. Physicians should receive training in basic medical genetics or genetic counseling through continuing education programs, enabling them to better educate patients about SCD and its genetic risks during consultations.\u003c/p\u003e\n\u003cp\u003ePublic awareness of SCD genetic testing can also be significantly improved through campaigns similar to the \u0026quot;Ice Bucket Challenge\u0026quot; or by leveraging media portrayals of SCD. Our survey indicates that some guiding questions and a brief educational segment convinced 47 individuals initially opposed to genetic testing to reconsider their stance.\u003c/p\u003e\n\u003cp\u003eThis perspective on public attitudes towards genetic testing for SCD is underrepresented in existing survey studies, highlighting a notable gap in the literature that our research seeks to address.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe novelty of this study\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study is the first in China, and possibly globally, to investigate public attitudes toward genetic testing for SCD. The research includes telephone follow-ups with 199 survivors or immediate family members of cardiac arrest victims and surveys of 536 members of the public regarding their attitudes toward SCD genetic testing.\u003c/p\u003e\n\u003cp\u003eThe novelty of this research lies in:\u003c/p\u003e\n\u003col style=\"list-style-type: lower-roman;\"\u003e\n \u003cli\u003e\u0026nbsp;\u003cstrong\u003eExtensive Survey Coverage\u003c/strong\u003e: This study includes not only the general public but also sudden cardiac arrest (SCA) survivors and immediate family members of SCA victims, unlike most surveys that focus solely on the public.\u003c/li\u003e\n \u003cli\u003e\u003cstrong\u003eInnovative Questionnaire Design\u003c/strong\u003e: We incorporated a quality control mechanism in the questionnaire by repeating the same question at the beginning and end to filter out invalid responses.\u003c/li\u003e\n \u003cli\u003e\u003cstrong\u003eEducational Content Integration\u003c/strong\u003e: The questionnaire included educational content and genetics questions to assess changes in public attitudes before and after exposure to scientific information.\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003eThe results provide valuable insights for China\u0026rsquo;s medical genetics education system and public health outreach, highlighting the crucial role of primary care physicians in both treating and preventing cardiovascular diseases. This underscores the need for continuing education in genetic counseling for cardiovascular specialists.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimitations and Future Research Directions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study has several limitations. First, as the survey was conducted via mobile phones, participants may not have fully engaged with the educational content, similar to quickly agreeing to app terms and conditions, possibly affecting attitude changes. Future surveys should track response times to ensure meaningful engagement.\u003c/p\u003e\n\u003cp\u003eSecond, the lack of involvement from attending cardiology physicians contributed to survivors\u0026apos; refusal to participate. Engaging these clinicians could enhance compliance and willingness. A similar survey involving cardiologists and nurses in cardiovascular departments may yield deeper insights into medical professionals\u0026rsquo; perspectives on genetic testing for SCD and identify educational needs.\u003c/p\u003e\n\u003cp\u003eLastly, the study was limited to Hangzhou in Zhejiang Province, potentially limiting the generalizability of findings due to regional and ethnic disparities in China. Future research should include a more diverse sample for broader applicability.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eData AVAILABILITY\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll data is made available via supplementary materials\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor Contributions Statement\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eXu-tao Hong was responsible for designing the questionnaire, writing and submitting the article. Xiao-ling Chen contributed to the telephone follow-up and questionnaire collection. Jian Huang, Shuang-yong Dong and Xiao-yan Xu contributed to recruiting respondents in the hospitals. Yan-bing He and Jin-yuan Wang contributed to extracting and analyzing data. Jian-gang Wang and Jun-geng Zhang collected and review the OHCA data. All the authors read and approved the final manuscript. Ming Qi and Jian-gang Wang provided the idea, and responsible for the whole study.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe study is supported by a grant from the Hangzhou Science and Technology Bureau (Project No. 20201203B187).\u003c/p\u003e\n\u003cp\u003eDian Diagnostic group, is an independent clinical laboratory (ICL).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthical Approval\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eStudies involving animal subjects Generated Statement: No animal studies are presented in this manuscript.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStudies involving human subjects\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eGenerated Statement: The studies involving human participants were reviewed and approved by the Ethics Staff Hangzhou Emergency center (serial number: HZEMC-2020-09).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting Interests\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eZhang S. 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Chinese geneticists\u0026apos; views of ethical issues in genetic testing and screening: evidence for eugenics in China. Am J Hum Genet. 1998; 63\u003cstrong\u003e:\u003c/strong\u003e 688-95.\u003c/li\u003e\n\u003cli\u003eLaskey SL, Williams J, Pierre-Louis J, O\u0026apos;Riordan M, Matthews A, Robin NH. Attitudes of African American premedical students toward genetic testing and screening. Genet Med. 2003; 5\u003cstrong\u003e:\u003c/strong\u003e 49-54.\u003c/li\u003e\n\u003cli\u003eBrunger JW, Murray GS, O\u0026apos;Riordan M, Matthews AL, Smith RJ, Robin NH. Parental attitudes toward genetic testing for pediatric deafness. Am J Hum Genet. 2000; 67\u003cstrong\u003e:\u003c/strong\u003e 1621-5.\u003c/li\u003e\n\u003cli\u003eCheung R, Jolly S, Vimal M, Kim HL, McGonigle I. Who\u0026apos;s afraid of genetic tests?: An assessment of Singapore\u0026apos;s public attitudes and changes in attitudes after taking a genetic test. BMC Med Ethics. 2022; 23\u003cstrong\u003e:\u003c/strong\u003e 5.\u003c/li\u003e\n\u003cli\u003eChokoshvili D, Belmans C, Poncelet R, Sanders S, Vaes D, Vears D et al. Public Views on Genetics and Genetic Testing: A Survey of the General Public in Belgium. Genet Test Mol Biomarkers. 2017; 21\u003cstrong\u003e:\u003c/strong\u003e 195-201.\u003c/li\u003e\n\u003cli\u003eKaufman D, Murphy J, Scott J, Hudson K. Subjects matter: a survey of public opinions about a large genetic cohort study. Genet Med. 2008; 10\u003cstrong\u003e:\u003c/strong\u003e 831-9.\u003c/li\u003e\n\u003cli\u003ePark S, Woo SC, Ban HJ, Lee S, Kim SY, Jin HJ. Perception on genetic testing in Korean medicine doctors: A mobile-based survey. Integr Med Res. 2021; 10\u003cstrong\u003e:\u003c/strong\u003e 100643.\u003c/li\u003e\n\u003cli\u003eNorman G. Likert scales, levels of measurement and the \u0026quot;laws\u0026quot; of statistics. Adv Health Sci Educ Theory Pract. 2010; 15\u003cstrong\u003e:\u003c/strong\u003e 625-32.\u003c/li\u003e\n\u003cli\u003eB\u0026iacute;r\u0026oacute; K, Dombr\u0026aacute;di V, Fekete Z, B\u0026aacute;nyai G, Boruzs K, Nagy A et al. Investigating the knowledge of and public attitudes towards genetic testing within the Visegrad countries: a cross-sectional study. BMC Public Health. 2020; 20\u003cstrong\u003e:\u003c/strong\u003e 1380.\u003c/li\u003e\n\u003cli\u003eNeumann PJ, Hammitt JK, Mueller C, Fillit HM, Hill J, Tetteh NA et al. Public attitudes about genetic testing for Alzheimer\u0026apos;s disease. Health Aff (Millwood). 2001; 20\u003cstrong\u003e:\u003c/strong\u003e 252-64.\u003c/li\u003e\n\u003cli\u003eHenneman L, Timmermans DR, Van Der Wal G. Public attitudes toward genetic testing: perceived benefits and objections. Genet Test. 2006; 10\u003cstrong\u003e:\u003c/strong\u003e 139-45.\u003c/li\u003e\n\u003cli\u003eHenneman L, Vermeulen E, van El CG, Claassen L, Timmermans DRM, Cornel MC. Public attitudes towards genetic testing revisited: comparing opinions between 2002 and 2010. Eur J Hum Genet. 2013; 21\u003cstrong\u003e:\u003c/strong\u003e 793-9.\u003c/li\u003e\n\u003cli\u003eHaga SB, Barry WT, Mills R, Ginsburg GS, Svetkey L, Sullivan J et al. Public Knowledge of and Attitudes Toward Genetics and Genetic Testing. Genet Test Mol Biomarkers. 2013; 17\u003cstrong\u003e:\u003c/strong\u003e 327-35\u003c/li\u003e\n\u003cli\u003eHong X: A questionnaire survey of gene testing for SCD, 2024.\u003c/li\u003e\n\u003cli\u003eAbdul Rahim HF, Ismail SI, Hassan A, Fadl T, Khaled SM, Shockley B et al. Willingness to participate in genome testing: a survey of public attitudes from Qatar. J Hum Genet. 2020; 65\u003cstrong\u003e:\u003c/strong\u003e 1067-73.\u003c/li\u003e\n\u003cli\u003eRoberts JS. Anticipating response to predictive genetic testing for Alzheimer\u0026apos;s disease: a survey of first-degree relatives. Gerontologist. 2000; 40\u003cstrong\u003e:\u003c/strong\u003e 43-52.\u003c/li\u003e\n\u003cli\u003eLi M, Zhao SX, Chen WJ, Huang TY, Chen LS. Knowledge and Attitudes toward Genetic Testing for Autism Spectrum Disorders among Parents of Affected Children in Taiwan. Genes (Basel). 2022; 13.\u003c/li\u003e\n\u003cli\u003ePress SRAPaETA: A 17-year-old Chinese player died after collapsing during a badminton match in Indonesia. https://abcnews.go.com/International/wireStory/17-year-chinese-player-died-after-collapsing-badminton-111568966: ABC News, 2024, Vol 2024.\u003c/li\u003e\n\u003cli\u003eEgger F, Scharhag J, Kastner A, Dvorak J, Bohm P, Meyer T. FIFA Sudden Death Registry (FIFA-SDR): a prospective, observational study of sudden death in worldwide football from 2014 to 2018. Br J Sports Med. 2022; 56\u003cstrong\u003e:\u003c/strong\u003e 80-7.\u003c/li\u003e\n\u003cli\u003ePriori SG, Napolitano C, Schwartz PJ, Grillo M, Bloise R, Ronchetti E et al. Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers. JAMA. 2004; 292\u003cstrong\u003e:\u003c/strong\u003e 1341-4.\u003c/li\u003e\n\u003cli\u003eGroffen AJ BH, Christiaans I: Long QT Syndrome Overview; in: Adam MP FJ, Mirzaa GM, et al. (ed): GeneReviews\u0026reg; [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024, 2003.\u003c/li\u003e\n\u003cli\u003eCharbonneau J, Nicol D, Chalmers D, Kato K, Yamamoto N, Walshe J et al. Public reactions to direct-to-consumer genetic health tests: A comparison across the US, UK, Japan and Australia. Eur J Hum Genet. 2020; 28\u003cstrong\u003e:\u003c/strong\u003e 339-48.\u003c/li\u003e\n\u003cli\u003eTiner JC, Mechanic LE, Gallicchio L, Gillanders EM, Helzlsouer KJ. Awareness and use of genetic testing: An analysis of the Health Information National Trends Survey 2020. Genet Med. 2022; 24\u003cstrong\u003e:\u003c/strong\u003e 2526-34.\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;Characteristics of the questionnaire (n=477\u003csup\u003ea\u003c/sup\u003e)\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"597\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCharacteristics\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWgt %\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.Age, years\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e122\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e25.6\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e26-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e141\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e29.6\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e36-50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e155\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e32.5\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eabove 50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e12.4\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2.Sex\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003efemale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e194\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e40.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003emale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e283\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e59.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3.Education level\u003c/strong\u003e\u003csup\u003eb\u003c/sup\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eHigh school or less\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e170\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e35.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003ecollege or above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e307\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e64.4\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e4.Career\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eHousewives\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e89\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e18.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eIT practitioners\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e87\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e8.2\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eDrivers\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e72\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e15.1\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eEmergency volunteers\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e126\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e26.4\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eCardiovascular patients\u0026apos; relatives\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e103\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e21.6\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e5.Income\u003c/strong\u003e\u003csup\u003ec\u003c/sup\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u0026lt;50k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e82\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e20.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e50-120k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e175\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e44.4\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u0026gt;120k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e137\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e34.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003ekeep secret\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e6.Medical_insurance\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eNo medicaid insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e23\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e4.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eRural Medical Insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e96\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e20.1\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eUrban Medical Insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e262\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e54.9\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eMedicaid plus commercial\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e96\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e20.1\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e7.Emergency volunteer certificate\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e316\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e66.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e161\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e33.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e8.Religious beliefs\u003c/strong\u003e\u003csup\u003ed\u003c/sup\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e322\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e68.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eonly believe in science\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e147\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e31.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e9.Have you ever heard of SCD\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eOnly seen in the news\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e337\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e70.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eI haven\u0026apos;t had any incidents around me, nor have I followed any similar news\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e42\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e8.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eamong colleagues or friends\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e80\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e16.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eamong immediate family members\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e3.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e10.Genetic quiz score\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u0026lt;=6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e285\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e59.8\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u0026gt;=7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e192\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e40.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e11.Have you ever heard that deafness, amyotrophic lateral sclerosis (ALS), color blindness, hemophilia, and thalassemia are genetic diseases?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e136\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e28.5\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e341\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e71.5\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e12.Have received genetic testing before\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e389\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e81.6\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 54.7739%;\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 26.2982%;\"\u003e\n \u003cp\u003e88\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 18.928%;\"\u003e\n \u003cp\u003e18.5\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003csup\u003ea\u003c/sup\u003e After removing the invalid questionnaires\u003c/p\u003e\n\u003cp\u003e\u003csup\u003eb\u003c/sup\u003e We combined the groups of \u0026lt;=9 year and \u0026lt;=12year\u003c/p\u003e\n\u003cp\u003e\u003csup\u003ec\u003c/sup\u003e We will not conduct further statistical analysis on the \u0026apos;keep secret\u0026apos; group\u003c/p\u003e\n\u003cp\u003e\u003csup\u003ed\u003c/sup\u003e We categorized \u0026lsquo;a little\u0026rsquo; and \u0026lsquo;keep secret\u0026rsquo; in the \u0026lsquo;religion option\u0026rsquo; as \u0026lsquo;having religious beliefs\u0026rsquo;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e2 Characteristics\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;for the telephone follow-up\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"602\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eEpidemiological features\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSurvivors\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e\u003cstrong\u003evictims\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePatients n (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e199\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e31 (15.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e168 (84.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGender n (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eMale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e141(71)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e116\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eFemale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e58(29)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e52\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge (Mean + IQR)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e32.7\u0026plusmn;8.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e31.86\u0026plusmn;9.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e32.98\u0026plusmn;8.15\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eLocation\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eHome\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e64(32.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e60\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003ePublic place\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e81(40.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e63\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eWorkplace\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e28(14)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eunclear\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e26(13)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e23\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWho made the emergency call\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eImmediate relatives\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e36(18.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e30\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eColleague, friends\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e26(13.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eforward our SMS\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e18(9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eReject our follow-up\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e8(4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003ePasser-by or public staff\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e69(34.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e/\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e/\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eMissing (out of service, no answered)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e68(34.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e/\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e/\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAttitude towards telephone follow-ups (n=52)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eWilling to participate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e19(36.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eCompleted genetic testing\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 42.691%;\"\u003e\n \u003cp\u003eReject\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.5914%;\"\u003e\n \u003cp\u003e33(63.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.4286%;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.289%;\"\u003e\n \u003cp\u003e31\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cbr\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e3 Different characteristics\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003eon the willingness to undergo SCD genetic testing\u003c/strong\u003e\u003c/p\u003e\n\u003ctable style=\"width: 104%;border-collapse: collapse;border: none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 37.38%;border-right: none;border-bottom: none;border-left: none;border-image: initial;border-top: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 31.85pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:justify;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style='font-size:12px;font-family:\"Times New Roman\";'\u003e \u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 20.24%;border-top: 1pt solid rgb(127, 127, 127);border-left: none;border-bottom: 1pt solid rgb(127, 127, 127);border-right: none;padding: 0in 5.4pt;height: 31.85pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ewhether agree to genetic testing for SCD, n (%)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 8.1%;border-right: none;border-bottom: none;border-left: none;border-image: initial;border-top: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 31.85pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ec\u003csup\u003e2\u003c/sup\u003e\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 11.62%;border-right: none;border-bottom: none;border-left: none;border-image: initial;border-top: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 31.85pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eP\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 22.66%;border-right: none;border-bottom: none;border-left: none;border-image: initial;border-top: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 31.85pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eOR (95%CI)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 29.65pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003eAgree\u003cbr\u003e\u0026nbsp;(N=366)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 29.65pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003eDisagree\u003cbr\u003e\u0026nbsp;(N=111)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eage, years\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e8.455\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.015\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e18-25\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e97(26.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e25(22.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.550(0.313, 0.967)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e26-35\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e96(26.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e45(40.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eabove 35\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e173(47.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e41(36.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.506(0.309, 0.826)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003esex\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e1.837\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.175\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003efemale\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e155(42.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e39(35.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003emale\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e211(57.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e72(64.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e1.356(0.872, 2.109)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eEducation level\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e2.834\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.092\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eHigh school or less\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e123(33.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e47(42.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003ecollege or above\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e243(66.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e64(57.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.689(0.446, 1.064)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eCareer\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eEmergency volunteers\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e110(30.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e16(14.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;font-family: DengXian;\"\u003e15.262\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;font-family: DengXian;\"\u003e0.004\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e2.538(1.257, 5.127)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eDrivers\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e48(13.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e24(21.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e3.437(1.677, 7.046)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eCardiovascular patients\u0026apos; relatives\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e82(22.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e21(18.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 15.55pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e1.761(0.865, 3.583)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eincome\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e3.583\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.167\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026lt;50k\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e65(20.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e17(21.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e50-120k\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e133(42.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e42(52.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.692(0.341, 1.405)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026gt;120k\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e116(36.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e21(26.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e1.207(0.639, 2.282)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003ekeep secret\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 20.24%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e83\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003emedical insurance\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e14.427\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eNo Medicaid Insurance\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e13(3.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e10(9.0)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eRural Medical Insurance\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e62(16.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e34(30.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.713(0.283, 1.797)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eUrban Medical Insurance\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e212(57.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e50(45.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.307(0.127, 0.739)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eMedicaid plus commercial\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e79(21.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e17(15.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.280(0.105, 0.743)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"font-size:12px;\"\u003eP for trend\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.047\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eEmergency volunteer certificate\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.631\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.427\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e239(65.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e77(69.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e127(34.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e34(30.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.831(0.526, 1.313)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eReligious beliefs\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e11.64\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e98(27.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e49(44.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eonly believe in science\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e261(72.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e61(55.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.467(0.300, 0.727)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eHave you ever heard of SCD\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e9.371\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.025\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eOnly seen in the news\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e269(73.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e68(61.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.372(0.190, 0.727)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 18.2pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eI haven\u0026apos;t had any incidents around me, nor have I followed any similar news\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 18.2pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e25(6.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 18.2pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e17(15.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 18.2pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eamong colleagues or friends or immediate family members\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e72(19.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e26(23.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.531(0.248, 1.138)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003egenetic score\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.263\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.608\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026lt;=6\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e221(60.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e64(57.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026gt;=7\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e145(39.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e47(42.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e1.119(0.727, 1.722)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003eHave you received genetic testing before\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e3.275\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.07\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e292(79.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e97(87.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border: none;padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;\"\u003ereference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 37.38%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;text-indent:.25in;'\u003e\u003cspan style=\"font-size:12px;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 10.48%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e74(20.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 9.74%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e14(12.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 8.1%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style='font-size:12px;font-family:\"Times New Roman\";'\u003e \u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.62%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style='font-size:12px;font-family:\"Times New Roman\";'\u003e \u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 22.66%;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(127, 127, 127);padding: 0in 5.4pt;height: 14.8pt;vertical-align: top;\"\u003e\n \u003cp style='margin:0in;text-align:left;font-size:14px;font-family:\"Times New Roman\",serif;'\u003e\u003cspan style=\"font-size:12px;\"\u003e0.570(0.308, 1.054)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eTable 4\u0026nbsp;Attitude change after science education\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"624\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" valign=\"bottom\" style=\"width: 227px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e \u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" valign=\"bottom\" style=\"width: 142px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eChange to agree, n (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003ec\u003csup\u003e2\u003c/sup\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003eP\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122px;\"\u003e\n \u003cp\u003eOR (95%CI)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003eDisagree\u003cbr\u003e\u0026nbsp;(N=64)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003eAgree\u003cbr\u003e\u0026nbsp;(N=47)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge, years\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.923\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.404\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e8(17.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e26-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e22(34.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e23(48.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003e2.221(0.798, 6.183)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e36-50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e12(25.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.500(0.490, 4.592)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eabove 50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e8(12.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e4(8.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.062(0.245, 4.599)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge, years\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.698\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e18-25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e8(17.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.450(0.162, 1.253)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e26-35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e22(34.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e23(48.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003eAbove 35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e25(39.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e16(34.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.612(0.260, 1.443)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eSex\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e3.259\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.071\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003eFemale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e18(28.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e21(44.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003eMale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e46(71.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e26(55.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.484(0.219, 1.070)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eEducation level\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.666\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.414\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eHigh school or less\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e25(39.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e22(46.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eCollege or above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e39(60.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e25(53.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.728(0.340, 1.560)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eCareer\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e5.932\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.204\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eHousewives\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e11(17.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e5(10.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eIT practitioners\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e16(25.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e10(21.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.375(0.367, 5.145)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eDrivers\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e11(17.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e13(27.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.600(0.689, 9.805)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eEmergency volunteers\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e7(14.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.906(0.229, 3.585)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eCardiovascular patients\u0026apos; relatives\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e9(14.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e12(25.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.933(0.749, 11.490)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eIncome*\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.288\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.866\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u0026lt;50k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e8(19.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e9(23.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e50-120k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e23(54.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e19(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.734(0.237, 2.272)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u0026gt;120k\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e11(26.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e10(26.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.808(0.225, 2.909)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eMedical insurance\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e3.355\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.34\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo Medicaid insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e7(10.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e3(6.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eRural Medical Insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e16(25.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e18(38.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.624(0.579, 11.890)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eUrban Medical Insurance\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e29(45.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e21(44.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.689(0.391, 7.306)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eMedicaid plus commercial\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e12(18.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e5(10.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.972(0.176, 5.365)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eA1\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003eEmergency volunteer certificate\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.997\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.318\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e42(65.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e35(74.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e22(34.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e12(25.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.655(0.284, 1.507)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eA2\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003eReligious beliefs\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;*\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.952\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.329\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e26(40.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e23(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eOnly believe in science\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e38(59.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e23(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.684(0.319, 1.468)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eA3\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;Have you ever heard of SCD\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.258\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.879\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eOnly seen in the news\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e10(15.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e7(14.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eI haven\u0026apos;t had any incidents around me, nor have I followed any similar news\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e38(59.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e30(63.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.128(0.384, 3.314)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eAmong colleagues or friends\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e16(26.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e10(21.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.893(0.256, 3.110)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenetic quiz score\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.123\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.726\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u0026lt;=6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e36(56.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e28(59.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u0026gt;=7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e28(43.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e19(40.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.872(0.406, 1.873)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003e(AE) Have you ever heard that deafness, amyotrophic lateral sclerosis (ALS), color blindness, hemophilia, and thalassemia are genetic diseases?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.61\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e22(34.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e14(29.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e42(65.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e33(70.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e1.235(0.549, 2.777)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003e(AF) Do you think these deaf, ALS, colorblind, and hemophilia patients should undergo genetic testing to find out the cause of the disease?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e31.95\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e47(73.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e9(19.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e38(80.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e11.671(4.679, 29.115)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003e(AG) Do you think relatives of people with deafness, ALS, color blindness, and hemophilia should do genetic testing before giving birth to the next generation to avoid giving birth to fetuses with similar conditions?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e19.281\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e39(60.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e9(19.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e25(39.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e38(80.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e6.586(2.723, 15.930)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003e\u003cstrong\u003e(AH) Many of the SCD of young people are also related to genetics, and the immediate relatives also have a certain probability of carrying the risk of sudden death\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e13.789\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u0026lt;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eDo not believe\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e47(73.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e18(38.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereference\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eBelieve\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e17(26.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e29(61.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e4.454(1.985, 9.997)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003e(AI) Have you receive genetic testing before\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e3.16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e0.076\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eNo\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e59(92.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e38(80.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e\u003cstrong\u003ereferrence\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\"\u003e\n \u003cp\u003eYes\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e5(7.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e9(19.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"bottom\"\u003e\n \u003cp\u003e2.795(0.870, 8.975)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"6\" valign=\"bottom\" style=\"width: 624px;\"\u003e\n \u003cp\u003e* Missing data were not included in the analysis\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Genetic testing, Sudden unexplained death, Whole Exome Sequencing (WES), Survey, Public attitude","lastPublishedDoi":"10.21203/rs.3.rs-5257725/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-5257725/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study investigated public attitudes towards genetic testing for sudden cardiac death (SCD) in China, particularly in the context of increasing cardiovascular disease incidence and the potential benefits of genetic testing for prevention and treatment. We conducted a telephone follow-ups targeted 199 out-of-hospital cardiac arrest (OHCA) cases in Hangzhou, and a public survey included 536 respondents from various demographic groups, including emergency volunteers, housewives, IT practitioners, Cardiovascular patients' relatives, and drivers. The telephone follow-up revealed a low participation rate in genetic testing among survivors and victims' immediate relatives. The public survey indicated a general lack of awareness and knowledge about genetics and genetic testing for SCD. Significant differences in attitudes were observed based on demographic factors such as age, health insurance, and occupations. Many respondents expressed concerns about the implications of genetic testing and a general distrust in medical recommendations. The study highlights the urgent need for enhanced public education on the importance of genetic testing for SCD and the development of more effective communication strategies to address public concerns. Increasing awareness and understanding of the benefits of genetic testing could improve acceptance and participation, ultimately aiding in the prevention and management of SCD in China.\u003c/p\u003e","manuscriptTitle":"Public views on genetics and genetic testing of sudden unexplained death: A survey of the public in China","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-10-28 09:15:23","doi":"10.21203/rs.3.rs-5257725/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"9f05bc98-67af-4c75-a5b9-8a12d2269631","owner":[],"postedDate":"October 28th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":39392173,"name":"Health sciences/Medical research/Genetics research"},{"id":39392174,"name":"Health sciences/Pathogenesis/Clinical genetics/Genetic testing"},{"id":39392175,"name":"Health sciences/Diseases/Cardiovascular diseases/Arrhythmias/Ventricular fibrillation"}],"tags":[],"updatedAt":"2024-11-26T17:25:44+00:00","versionOfRecord":[],"versionCreatedAt":"2024-10-28 09:15:23","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5257725","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5257725","identity":"rs-5257725","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}