Endometriosis: Small rise in birth defects is observed in babies born to women with the condition

Jacqui Wise, Wise J
BMJ (Clinical research ed.) · 2026 · vol. 393 , pp. s934 · doi:10.1136/bmj.s934 · PMID:42128458 · W7161013280
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-21 ⓘ

Babies born to mothers with endometriosis exhibit a small increase in birth defects compared to those without the condition.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-24 · read from full text ⓘ

This BMJ report summarizes a Canadian population-based analysis of more than 1.4 million births in Ontario from 2006 to 2021, comparing babies born to women with endometriosis versus those born to women without the condition. The key finding is that congenital anomalies were observed at a slightly higher risk in the endometriosis group, with cleft palate highlighted as an example. The article provides high-level context about endometriosis prevalence and diagnostic delay in the UK, but explicit methodological caveats and effect-size details are not included in the provided text. This paper is centrally about endometriosis — it reports a small increase in birth defects, including cleft palate, among infants born to women with endometriosis.

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Endometriosis: Small rise in birth defects is observed in babies born to women with the condition BMJ 2026; 393 doi: https://doi.org/10.1136/bmj.s934 (Published 13 May 2026) Cite this as: BMJ 2026;393:s934- Jacqui Wise - Kent Babies born to women with endometriosis have a slightly higher risk of having a congenital anomaly such as cleft palate than those born to women without the condition, a Canadian study suggests.1 Endometriosis is a chronic inflammatory condition where endometrial-like tissue grows outside the uterus. One in 10 women in the UK are estimated to have endometriosis, but it takes an extraordinary average of nine years and four months from the first GP appointment for a patient to get a diagnosis, said the charity Endometriosis UK. The latest study analysed population data from more than 1.4 million births in Ontario from 2006 to 2021, of … Log in Log in using your username and password Log in through your institution Subscribe from £184 * Subscribe and get access to all BMJ articles, and much more. * For online subscription Access this article for 1 day for: £50 / $60/ €56 (excludes VAT) You can download a PDF version for your personal record.

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endometriosis

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