Endometriosis

In: AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh · 2021 · vol. 7(2) , pp. 1–12 · doi:10.29103/averrous.v7i2.5101 · W4285614918
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Endometriosis is the abnormal growth of endometrial tissue outside the uterus, causing symptoms like pain and infertility, diagnosed via laparoscopy, and managed with rest, nutrition, hygiene, medication, or surgery.

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This paper is a narrative overview describing endometriosis as abnormal growth of endometrial tissue outside the uterine cavity, focusing on its typical symptoms (chronic pelvic pain, dysmenorrhea, dyspareunia, dysuria, and dysexia) and common clinical problems (pain and infertility) in women of reproductive age. It states that the pathogenesis is not yet clearly explained and notes laparoscopy as the diagnostic “gold standard,” while acknowledging that available treatments do not guarantee permanent cure. The paper outlines management as non-pharmacologic measures (rest, nutritious diet, personal hygiene) and pharmacologic options (symptomatic and hormonal therapy), with surgery as an additional option, while not specifying quantitative outcomes. This paper is centrally about endometriosis — it summarizes the condition’s definition, symptoms, diagnostic approach, and treatment options.

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Abstract

Endometriosis merupakan pertumbuhan yang abnormal dari jaringan endometrium di luar cavum uteri. Endometriosis sering terjadi pada wanita usia reproduktif namun belum dapat dijelaskan secara pasti patogenesis terjadinya endometriosis. Gejala klinis paling umum yang terjadi pada penderita endometriosis adalah nyeri dan infertilitas. Nyeri yang ditimbulkan dapat berupa nyeri panggul kronis, dismenorea, dispareunia, disuria, dan diskezia. Laparoskopi merupakan baku emas dalam penegakan diagnosis dari endomeriosis. Tatalaksana yang diberikan pada pasien endometriosis tidak menjamin kesembuhan yang permanen. Tatalaksana yang dapat diberikan berupa tatalaksana non farmakologi berupa istirahat yang cukup, makan makanan yang bergizi, serta menjaga personal hygiene. Tatalaksana farmakologi berupa terapi simtomatik dan hormonal. Selain itu juga dapat dilakukan terapi pembedahan.
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Endometriosis DOI: https://doi.org/10.29103/averrous.v7i2.5101Keywords: endometriosis, nyeri, infertilitasAbstract Endometriosis merupakan pertumbuhan yang abnormal dari jaringan endometrium di luar cavum uteri. Endometriosis sering terjadi pada wanita usia reproduktif namun belum dapat dijelaskan secara pasti patogenesis terjadinya endometriosis. Gejala klinis paling umum yang terjadi pada penderita endometriosis adalah nyeri dan infertilitas. Nyeri yang ditimbulkan dapat berupa nyeri panggul kronis, dismenorea, dispareunia, disuria, dan diskezia. Laparoskopi merupakan baku emas dalam penegakan diagnosis dari endomeriosis. Tatalaksana yang diberikan pada pasien endometriosis tidak menjamin kesembuhan yang permanen. Tatalaksana yang dapat diberikan berupa tatalaksana non farmakologi berupa istirahat yang cukup, makan makanan yang bergizi, serta menjaga personal hygiene. Tatalaksana farmakologi berupa terapi simtomatik dan hormonal. Selain itu juga dapat dilakukan terapi pembedahan. References Prawirohardjo S. Ilmu Kandungan. 3rd ed. Anwar M, editor. Jakarta: PT Bina Pustaka Sarwono Prawirohardjo; 2011. 239-249 p. Wu IB, Tendean HMM, Mewengkang ME. Gambaran Karakteristik Penderita Endometriosis di RSUP Prof. Dr. R. D. Kandou Manado. J e-Clinic. 2017;5(2):279-85. Hendarto H. Endometriosis dari Aspek Teori Sampai Penanganan Klinis. Surabaya: Airlangga University Press; 2015. Djuwantono T. Manjemen Endometriosis untuk Meningkatkan Kualitas Hidup Wanita Penderita Endometriosis. Contin Med Educ Act. 2015;(April). Luqyana SD, Rodiani. Diagnosis dan Tatalaksana Terbaru Endometriosis. JIMKI. 2019;7(2):67-75. Kralickova M, Vetvicka V. Immunological Aspects of Endometriosis: A Review. Ann Transl. 2015;3(11):153. Tanbo T, Fedorcsak P. Endometriosis-Associated Infertility: Aspects of Pathophysiological Mechanisms and Treatment Options. Acta Obstet Gynecol Scand. 2017;96(6):659-67. Setya LK, Wardhani T, Annas JY. Profil Pasien Endometriosis dengan Riwayat Dysmenorrhea di Poli Infertilitas-Endokrin RSUD dr. Soetomo Surabaya Periode Januari-Desember 2014. 2014; Pangemanan G, Loho M, Wagey FW. Profil Penderita Endometriosis di RSUP Prof . Dr . R . D . Kandou Manado pada Tahun 2011-2015. Juernal e-Clinic. 2017;5(1):16-21. Wenqian X, Ling Z, Lan Y, Wei X, Yicun M, Yao X, et al. Estradiol Promotes Cells Invasion by Activating b-Catenin Signaling Pathway in Endometriosis. Reproduction. 2015;150:507-16. Abadi KC. Gambaran Endometriosis di Laboratorium Patologi Anatomi RSUP dr. M. Djamil Padang Periode 2010-2013. Universitas Andalas; 2014. Classification of Endometriosis [Internet]. Indian Centre for Endometriosiis. [cited 2021 Mar 25]. Available from: https://www.endometriosis-india.com/classification-of-endometriosis/ Rahmawati DS. Gambaran Karakteristik dan Pencarian Pelayanan Kesehatan pada Penderita Endometriosis di Klinik Fertilitas Graha Amerta RSUD dr. Soetomo Surabaya. Universitas Airlangga; 2016. Wedyawati UP. Analisis Penanganan Endometriosis dan Dampaknya pada Kesuburan Wanita. 2015; Downloads Published Issue Section License Authors retain copyright and grant the journal right of first publication and this work is licensed under a Creative Commons Attribution-ShareAlike 4.0 that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. All articles in this journal may be disseminated by listing valid sources and the title of the article should not be omitted. The content of the article is liable to the author. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work. In the dissemination of articles, the author must declare the AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Journal as the first party to publish the article.

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endometriosis

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