A comparative study of cement-augmented pedicle screw fixation combined with vertebroplasty and PKP alone in the treatment of osteoporotic vertebral burst fracture

AbstractTo compare the clinical efficacy of cement-augmented pedicle screw fixation combined with vertebroplasty (PS-VP) and PKP alone in the treatment of osteoporotic vertebral burst fracture (OVBF), The clinical data of 41 OVBF patients admitted to our department from January 2017 to December 2022 were retrospectively analyzed, including 18 patients who underwent PS-VP and 23 patients who underwent PKP alone. The age, BMI, LSS, NRS, ODI, KA and AHR were compared between the two groups to assess the efficacy of the two procedures. The differences between the postoperative clinical indicators of the two procedures were statistically significant compared with the preoperative ones (P＜0.05). The NRS, ODI, KA and AHR showed great difference between the two groups at 6 months postoperatively(P＜0.05). The KA and AHR in the PS-VP group at 6 months postoperatively were close to those at 3 days (P＞0.05), whereas the KA in the PKP alone group at 6 months postoperatively was larger and AHR was lower than that at 3 days postoperatively with statistical significance (P＜0.05). To conclude, there is no significant difference in the near-term efficacy between PS-VP and PKP alone for OVBF, but the former has advantages in improving clinical symptoms and dysfunction, restoring height of the injured vertebra and maintaining spinal loading capacity in the medium and long term.