Interrupted Aza-Wittig Reactions Using Iminophosphoranes to Synthesize 11C-Carbonyls
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OA: closed
CC-BY-NC-ND-4.0
Abstract
Iminophosphoranes are reported as convenient precursors to amides, ureas, carbamates and other carbonyl-containing molecules through CO2-fixation. Key to this transformation with stable isotopes and carbon-11 is interception of the reactive isocyanate intermediate. Automated synthesis and isolation of PET radiopharmaceuticals is achieved.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-24T02:00:01.246996+00:00
License: CC-BY-NC-ND-4.0