Independent Association Between Malnutrition Inflammation Score And C Reactive Protein/Albumin Ratio In Hemodialysis Patients

Objective: At this study we aimed to investigate relationship between Malnutrition Inflammation Score (MIS), C reactive protein /albumin ratio (CAR), albumin, CRP and other biochemical parameters at hemodialysis patients.Design and Methods66 ESRD patients on maintenance hemodialysis has been recruited to the study. MIS, biochemical parameters and CAR were analyzed.ResultsStatistically significant positive correlation was found between CAR and MIS≥7 (r=0.413, p=0.026), with CRP and MIS≥7 (r=0.388, p=0.038) and negative correlation was found with albumin and MIS (r=-0.511, p=0.005). For MIS, CAR, albumin and CRP a multiple regression ANOVA model was conducted to examine that relation of CAR, CRP, albumin on MIS (F=6.432, p=0.002). ANOVA model was found statistically significant (r=0.660, p=0.002). Variables CAR (p=0.003), albumin (p=0.008) and CRP(p=0.003) was found significant in the ANOVA model.ConclusionOur study showed first time in the literature that CAR is independently associated with MIS in HD patients.