WITHDRAWN: Craniotomy in Semi-Sitting Position: A 4-year Single Institution Experience

preprint OA: closed CC-BY-4.0

Abstract

Abstract Objectives The aim of our study was to determine patient outcomes after surgery performed in the semi-sitting position in our institution in the previous 4 years. Primarily we aimed to quantify our experience in terms of surgical and anesthesia (clinical) outcomes. Secondarily we sought to evaluate any major complications that may have occurred. Background We are an academic hospital where the neurosurgical case load on average exceeds 1000 surgeries annually, with strong adherence to internationally determined clinical quality metrics. A multidisciplinary team comprising dedicated neuroanesthetists, neurophysiologists and surgical nurses, delivers care for every neurosurgical patient. As part of our neuroanesthesia departmental self-review, we retrospectively sought to assess the outcomes of patients undergoing craniotomy in sitting position from 2019 to present. The study focused on perioperative outcomes and complications associated with craniotomy in sitting position. Method The electronic medical record database was retrospectively reviewed. Beginning from 2019, all adult patients who underwent craniotomy in sitting position were included. Individual patient charts were examined for significant events during the intraoperative and postoperative period. Any critical or adverse events were recorded. Demographic and clinically important findings were tabulated in an excel sheet. The study dataset was descriptively analyzed with the quantitative data represented as mean ± standard deviation and the qualitative data as valid percentages from the total cohort. A possible parametric comparison of gender vs length of ICU stay, length of hospital stay and duration of was done using student T-test were found be non-significance at 95% confidence level. All the analysis was carried out using IBM Statistical Package for the Social Sciences (SPSS) ® Edition 22. Results A total of 10 patients underwent craniotomy in sitting position from 2019 till date. Induction and maintenance of general anesthesia were accomplished with total intravenous anesthesia using target-controlled infusion with remifentanil and propofol. The patients’ demographics, diagnosis and complications were evaluated. Nine of 10 patients had pneumocephalus with one patient developing severe manifestations. One patient had clinically significant venous air embolism with severe manifestations including massive pleural effusion. Except for one patient, all were extubated at end of surgery. Conclusions During the last four years our neuroanesthesia team recorded 10 craniotomies in sitting position. Ninety percent of patients were managed without any major long-term sequelae. We concluded that sitting position for craniotomy is not without its challenges. However, a dedicated and experienced team can manage possible complications and improve patient outcomes.
Full text 11,523 characters · extracted from preprint-html · click to expand
WITHDRAWN: Craniotomy in Semi-Sitting Position: A 4-year Single Institution Experience | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article WITHDRAWN: Craniotomy in Semi-Sitting Position: A 4-year Single Institution Experience Arunabha Karmakar, Muhammad Jaffar Khan, Ayten Saracoglu, Merve Ergenc, and 5 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3821842/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Editorial Note The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. Editorial notes are used to provide important context regarding the topic of a preprint or to alert readers to potential issues concerning that preprint or a downstream publication associated with it. For more information on editorial notes, see our Editorial Policies . Abstract The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. Full Text The authors have withdrawn this preprint from Research Square. Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3821842","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":445760402,"identity":"31d227a1-75d3-4912-b803-9a45db3b6e95","order_by":0,"name":"Arunabha Karmakar","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA5klEQVRIiWNgGAWjYBACNokEEAUk2HsMgAxmBn5CWvglDkC18JyBaJFsIKBFcmYDVItEDkSLwQECWgxuMz/7dKMmTd585htDIMOaweA4AT0G99iMZ+ccyzGcczv/s3TOsXQGgzMJhLQwGDPnsFUwzpDOMZDOYTsMdBgBLfa32T8z5/yrsJ8hecb4d86/wwxm5x8QsOVmjzFzbltO4gwJHjPp3LbDDMY3CDnsxpli5ty+tOQZPDlm1rl96TySMwjZciN9M3POt2TbGexnjG/nfLOW4/cnYAsG4CFR/SgYBaNgFIwCbAAA5lFG1fC7kXEAAAAASUVORK5CYII=","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":true,"prefix":"","firstName":"Arunabha","middleName":"","lastName":"Karmakar","suffix":""},{"id":445760403,"identity":"a3e40408-8d92-4170-811b-796b867b892d","order_by":1,"name":"Muhammad Jaffar Khan","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Muhammad","middleName":"Jaffar","lastName":"Khan","suffix":""},{"id":445760404,"identity":"fd2b3fc9-ad06-462d-98d6-9c57d0bbff7a","order_by":2,"name":"Ayten Saracoglu","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Ayten","middleName":"","lastName":"Saracoglu","suffix":""},{"id":445760405,"identity":"df5a3099-d4d6-41e4-828c-128566c05ae2","order_by":3,"name":"Merve Ergenc","email":"","orcid":"","institution":"Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital","correspondingAuthor":false,"prefix":"","firstName":"Merve","middleName":"","lastName":"Ergenc","suffix":""},{"id":445760406,"identity":"0f39adcb-f2dd-4098-8130-e5c1ea7023f6","order_by":4,"name":"Mogahed Ismail Hassan Hussein","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Mogahed","middleName":"Ismail Hassan","lastName":"Hussein","suffix":""},{"id":445760407,"identity":"1e5ae9f8-226a-4adc-a959-e1d045af14a4","order_by":5,"name":"Mohammed Janish","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Mohammed","middleName":"","lastName":"Janish","suffix":""},{"id":445760408,"identity":"9bced045-6195-47b2-8e75-081d4e02f3b8","order_by":6,"name":"Kemal Tolga Saracoglu","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Kemal","middleName":"Tolga","lastName":"Saracoglu","suffix":""},{"id":445760409,"identity":"1ea05385-8d19-4e96-92aa-cb6b0085d7f5","order_by":7,"name":"Kishore Kumar Gangineni","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Kishore","middleName":"Kumar","lastName":"Gangineni","suffix":""},{"id":445760410,"identity":"571021c6-39fa-4734-bfba-b7ed5c54bc93","order_by":8,"name":"Neeraj Kumar","email":"","orcid":"","institution":"Hamad Medical Corporation","correspondingAuthor":false,"prefix":"","firstName":"Neeraj","middleName":"","lastName":"Kumar","suffix":""}],"badges":[],"createdAt":"2023-12-29 16:14:10","currentVersionCode":2,"declarations":"","doi":"10.21203/rs.3.rs-3821842/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-3821842/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. ","failedWorkflow":false,"files":[{"id":81037745,"identity":"0fb4773a-2ba0-46f7-89c4-eb2c8c482b62","added_by":"auto","created_at":"2025-04-21 12:43:46","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":207275,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3821842/v2/d3a2da8a-4c07-4796-ad5c-143636c700df.pdf"},{"id":81037743,"identity":"56da9fdb-1578-4c60-83e4-a473164d8916","added_by":"auto","created_at":"2025-04-21 12:43:45","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":207275,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3821842/v2/1d6dc410-f1e2-41de-840e-725de8f5127c.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"WITHDRAWN: Craniotomy in Semi-Sitting Position: A 4-year Single Institution Experience","fulltext":[{"header":"Full Text","content":"The authors have withdrawn this preprint from Research Square."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":true,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":true,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-3821842/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3821842/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. ","manuscriptTitle":"WITHDRAWN: Craniotomy in Semi-Sitting Position: A 4-year Single Institution Experience","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2025-04-21 12:43:40","doi":"10.21203/rs.3.rs-3821842/v2","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2024-01-09 19:39:00","doi":"10.21203/rs.3.rs-3821842/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"9c6778d8-7d92-4723-96d1-35c5e9447894","owner":[],"postedDate":"April 21st, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-04-21T12:43:40+00:00","versionOfRecord":[],"versionCreatedAt":"2025-04-21 12:43:40","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v2","identity":"rs-3821842","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-3821842","identity":"rs-3821842","version":["v2"]},"buildId":"qtupq5eGEP_6zYnWcrvyt","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2024) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
unpaywall
last seen: 2026-05-24T02:00:01.246996+00:00
License: CC-BY-4.0