Medication Adherence Among Type 2 Diabetes Patients Attending a Tertiary Care Hospital Mysuru- a Cross- Sectional Study

Medication Adherence Among Type 2 Diabetes Patients Attending a Tertiary Care Hospital Mysuru- a Cross- Sectional Study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Medication Adherence Among Type 2 Diabetes Patients Attending a Tertiary Care Hospital Mysuru- a Cross- Sectional Study Divya Kulkarni, Santhosh Kumar A This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-9134171/v1 This work is licensed under a CC BY 4.0 License Status: Under Revision Version 1 posted 10 You are reading this latest preprint version Abstract Background: Diabetes is a chronic health condition that affects millions of people worldwide. It's a condition that knows no boundaries, striking across age, gender, and cultural differences. The prevalence of diabetes has been steadily rising, making it a global health concern. India has become diabetic capital of the world, surpassing China. Most of diabetic patients can be managed by proper life style practices, adhering to OHA, and practicing appropriate self-care practices like die, regular exercise, and periodic foot examination. Objectives : 1) To assess adherence to Medication. 2) To study the factors associated with drug adherence among study population Methods – A cross sectional study conducted among Type 2 Diabetes patients > 18 years who are on medications (both OHA and Insulin) for at least 1 year attending the medical OPD of Government medical college Hospital, Mysuru. Sample size of 254 was calculated based on prevalence of good self-care practices of 60%. Considering non-response rate of 10%, the total sample size was 280. Information regarding drug adherence will be collected after taking consent using pre-tested and validated Medication Compliance Questionnaire (MAC) respectively. Data entry and statistical analysis will be done by using SPSS (trail version) software. Results and Conclusion : Among 280 patients with type 2 diabetes mellitus (mean age 53.19 ± 13.3 years; 56.8% males), 65.0% were non-adherent to prescribed antidiabetic medications. Most participants were on oral hypoglycemic agents (83.2%), and 15.0% reported using alternate systems of medicine. Medication adherence was significantly associated with educational status ( p = 0.009), socio-economic status ( p < 0.001), body mass index ( p = 0.026), and type of medication ( p < 0.001). No significant association was observed with age, sex, marital status, occupation, or duration of diabetes. Type 2 Diabetes OHA Insulin Drug Adherence MAC Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Under Revision Version 1 posted Editorial decision: Revision requested 14 May, 2026 Reviews received at journal 10 May, 2026 Reviews received at journal 03 May, 2026 Reviewers agreed at journal 02 May, 2026 Reviewers agreed at journal 28 Apr, 2026 Reviewers invited by journal 27 Apr, 2026 Editor invited by journal 09 Apr, 2026 Editor assigned by journal 07 Apr, 2026 Submission checks completed at journal 07 Apr, 2026 First submitted to journal 07 Apr, 2026 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-9134171","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":633774130,"identity":"72c37206-04ed-4b33-97ae-59c495d2773f","order_by":0,"name":"Divya Kulkarni","email":"data:image/png;base64,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","orcid":"","institution":"Shri BM Patil Medical College","correspondingAuthor":true,"prefix":"","firstName":"Divya","middleName":"","lastName":"Kulkarni","suffix":""},{"id":633774131,"identity":"124ff0c0-7b55-494c-952d-3d4be2409a33","order_by":1,"name":"Santhosh Kumar A","email":"","orcid":"","institution":"Mysore Medical College","correspondingAuthor":false,"prefix":"","firstName":"Santhosh","middleName":"Kumar","lastName":"A","suffix":""}],"badges":[],"createdAt":"2026-03-16 07:10:10","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-9134171/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-9134171/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":108592675,"identity":"5c4c48f9-8a3c-48d3-8039-b1a6a2b7d5f6","added_by":"auto","created_at":"2026-05-06 09:59:30","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":343225,"visible":true,"origin":"","legend":"","description":"","filename":"01ManuscriptDSK.pdf","url":"https://assets-eu.researchsquare.com/files/rs-9134171/v1_covered_9c7ec4b6-d676-4b00-b584-f03e2f4b8db2.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"\u003cp\u003eMedication Adherence Among Type 2 Diabetes Patients Attending a Tertiary Care Hospital Mysuru- a Cross- Sectional Study\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"discover-public-health","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"","sideBox":"Learn more about [Discover Public Health](https://link.springer.com/journal/12982)","snPcode":"12982","submissionUrl":"https://submission.springernature.com/new-submission/12982/3","title":"Discover Public Health","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Discover Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Type 2 Diabetes, OHA, Insulin, Drug Adherence, MAC","lastPublishedDoi":"10.21203/rs.3.rs-9134171/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-9134171/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cu\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e\u003c/u\u003e\u003c/p\u003e\n\u003cp\u003eDiabetes is a chronic health condition that affects millions of people worldwide. It's a condition that knows no boundaries, striking across age, gender, and cultural differences. The prevalence of diabetes has been steadily rising, making it a global health concern. India has become diabetic capital of the world, surpassing China. Most of diabetic patients can be managed by proper life style practices, adhering to OHA, and practicing appropriate self-care practices like die, regular exercise, and periodic foot examination.\u003c/p\u003e\n\u003cp\u003e\u003cu\u003e\u003cstrong\u003eObjectives\u003c/strong\u003e\u003c/u\u003e: 1) To assess adherence to Medication. 2) To study the factors associated with drug adherence among study population\u003c/p\u003e\n\u003cp\u003e\u003cu\u003e\u003cstrong\u003eMethods\u003c/strong\u003e\u003c/u\u003e– A cross sectional study conducted among Type 2 Diabetes patients \u003cu\u003e\u0026gt;\u003c/u\u003e18 years who are on medications (both OHA and Insulin) for at least 1 year attending the medical OPD of Government medical college Hospital, Mysuru. Sample size of 254 was calculated based on prevalence of good self-care practices of 60%. Considering non-response rate of 10%, the total sample size was 280. Information regarding drug adherence will be collected after taking consent using pre-tested and validated Medication Compliance Questionnaire (MAC) respectively. Data entry and statistical analysis will be done by using SPSS (trail version) software.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults and Conclusion\u003c/strong\u003e: Among 280 patients with type 2 diabetes mellitus (mean age 53.19 ± 13.3 years; 56.8% males), 65.0% were non-adherent to prescribed antidiabetic medications. Most participants were on oral hypoglycemic agents (83.2%), and 15.0% reported using alternate systems of medicine. Medication adherence was significantly associated with educational status (\u003cem\u003ep\u003c/em\u003e = 0.009), socio-economic status (\u003cem\u003ep\u003c/em\u003e\u0026lt; 0.001), body mass index (\u003cem\u003ep\u003c/em\u003e = 0.026), and type of medication (\u003cem\u003ep\u003c/em\u003e\u0026lt; 0.001). No significant association was observed with age, sex, marital status, occupation, or duration of diabetes.\u003c/p\u003e","manuscriptTitle":"Medication Adherence Among Type 2 Diabetes Patients Attending a Tertiary Care Hospital Mysuru- a Cross- Sectional Study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2026-05-06 09:59:12","doi":"10.21203/rs.3.rs-9134171/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2026-05-14T08:06:22+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-05-10T10:02:44+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-05-04T01:27:16+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"262501503970055047960127108009301626916","date":"2026-05-02T09:04:01+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"69390442095871732343453092176615081318","date":"2026-04-28T09:11:05+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2026-04-27T07:36:34+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2026-04-09T07:37:37+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2026-04-08T02:05:41+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2026-04-07T06:17:29+00:00","index":"","fulltext":""},{"type":"submitted","content":"Discover Public Health","date":"2026-04-07T06:06:14+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"discover-public-health","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"","sideBox":"Learn more about [Discover Public Health](https://link.springer.com/journal/12982)","snPcode":"12982","submissionUrl":"https://submission.springernature.com/new-submission/12982/3","title":"Discover Public Health","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Discover Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"9861c71a-2efe-4ab7-923a-95554a2a26e8","owner":[],"postedDate":"May 6th, 2026","published":true,"recentEditorialEvents":[{"type":"decision","content":"Revision requested","date":"2026-05-14T08:06:22+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-05-10T10:02:44+00:00","index":71,"fulltext":""},{"type":"editorInvitedReview","content":"","date":"2026-05-04T01:27:16+00:00","index":70,"fulltext":""},{"type":"reviewerAgreed","content":"262501503970055047960127108009301626916","date":"2026-05-02T09:04:01+00:00","index":58,"fulltext":""}],"rejectedJournal":[],"revision":"","amendment":"","status":"in-revision","subjectAreas":[],"tags":[],"updatedAt":"2026-05-14T08:10:00+00:00","versionOfRecord":[],"versionCreatedAt":"2026-05-06 09:59:12","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-9134171","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-9134171","identity":"rs-9134171","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}