Progesterone receptor modulators
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AI-generated summary
This patent discloses progesterone receptor modulating steroids with dual agonistic and antagonistic activities, specifically identifying their utility in treating endometriosis, gynecological disorders, hormone replacement therapy, and contraception.
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Abstract
Disclosed are progesterone receptor modulating steroids of formula (I) which have both agonistic and antagonistic modulating activities towards the progesterone receptor, processes for their preparation, and their use in therapy, wherein the variables shown in formula (I) are as defined in the specification. These compounds of formula (I) are suitable for the treatment of endometriosis, for hormone replacement therapy or for the treatment of a gynaecological disorder, and as a contraceptive.
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- europepmc
- last seen: 2026-10-11T09:27:45.537177+00:00