Reproductive endocrinology and infertility: Management of polycystic ovarian syndrome (pcos), endometriosis, and advances in assisted reproductive technologies

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This review synthesizes current evidence to discuss reproductive endocrinology principles, the pathogenesis and management of polycystic ovarian syndrome and endometriosis, and modern innovations in assisted reproductive technologies.

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This review article synthesizes current evidence from the last decade regarding reproductive endocrinology and infertility management. It details the pathogenesis and treatment strategies for two prevalent disorders: polycystic ovarian syndrome, characterized by hormonal and metabolic dysfunction, and endometriosis, defined by ectopic endometrial tissue causing inflammation and pain. The paper also discusses significant advancements in assisted reproductive technologies, such as in vitro fertilization and cryopreservation, which have improved pregnancy outcomes for patients with these conditions. Relevance to endometriosis: listed as one of the primary conditions discussed alongside PCOS, with specific attention paid to its role in pelvic pain and infertility management.

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Abstract

Reproductive endocrinology represents a critical subspecialty within obstetrics and gynecology that focuses on hormonal regulation of reproduction and the management of infertility. Among the most prevalent and clinically significant disorders affecting female fertility are polycystic ovarian syndrome (PCOS) and endometriosis. PCOS is a complex endocrine and metabolic disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, affecting up to 15 to 20 percent of reproductive-aged women worldwide. Endometriosis is a chronic inflammatory condition defined by the presence of endometrial-like tissue outside the uterine cavity and is strongly associated with pelvic pain and infertility. Over the past decade, substantial progress has been made in understanding the pathophysiology of these conditions and in refining their management strategies. Simultaneously, assisted reproductive technologies (ART), including in vitro fertilization, intracytoplasmic sperm injection, preimplantation genetic testing, and cryopreservation, have undergone remarkable advancements, improving pregnancy outcomes and expanding reproductive options. This review synthesizes current evidence from the last ten years to provide a comprehensive discussion of reproductive endocrinology principles, the pathogenesis and management of PCOS and endometriosis, and modern innovations in ART.
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Reproductive endocrinology and infertility: Management of polycystic ovarian syndrome (pcos), endometriosis, and advances in assisted reproductive technologies Authors/Creators - 1. Associate Professor, Shivalik Institute of Nursing, Shimla, Himachal Pradesh - 2. Nursing Officer, AIIMS Raipur, Chhattisgarh - 3. Professor OBG, Kamdar College of Nursing Rajkot, Gujrat Description Reproductive endocrinology represents a critical subspecialty within obstetrics and gynecology that focuses on hormonal regulation of reproduction and the management of infertility. Among the most prevalent and clinically significant disorders affecting female fertility are polycystic ovarian syndrome (PCOS) and endometriosis. PCOS is a complex endocrine and metabolic disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, affecting up to 15 to 20 percent of reproductive-aged women worldwide. Endometriosis is a chronic inflammatory condition defined by the presence of endometrial-like tissue outside the uterine cavity and is strongly associated with pelvic pain and infertility. Over the past decade, substantial progress has been made in understanding the pathophysiology of these conditions and in refining their management strategies. Simultaneously, assisted reproductive technologies (ART), including in vitro fertilization, intracytoplasmic sperm injection, preimplantation genetic testing, and cryopreservation, have undergone remarkable advancements, improving pregnancy outcomes and expanding reproductive options. This review synthesizes current evidence from the last ten years to provide a comprehensive discussion of reproductive endocrinology principles, the pathogenesis and management of PCOS and endometriosis, and modern innovations in ART. Files 1. SJ067-SJOPNN-V4-I1.pdf Files (185.2 kB) | Name | Size | Download all | |---|---|---| | md5:eb492ccf9e30d63d290cfa55590a4b00 | 185.2 kB | Preview Download |

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last seen: 2026-06-10T17:14:06.276822+00:00
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